Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   FGL89_RS05735 Genome accession   NZ_CP042374
Coordinates   1143606..1145732 (+) Length   708 a.a.
NCBI ID   WP_014974922.1    Uniprot ID   K0DF82
Organism   Leuconostoc carnosum strain CBA3620     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1138606..1150732
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL89_RS05700 (FGL89_05700) - 1138694..1139800 (+) 1107 WP_147000465.1 AI-2E family transporter -
  FGL89_RS05715 (FGL89_05715) - 1140309..1140665 (+) 357 WP_014974926.1 PadR family transcriptional regulator -
  FGL89_RS05720 (FGL89_05720) - 1140643..1141491 (+) 849 WP_014974925.1 membrane protein -
  FGL89_RS05725 (FGL89_05725) rlmD 1141532..1143022 (-) 1491 WP_014974924.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  FGL89_RS05730 (FGL89_05730) - 1143326..1143550 (+) 225 WP_014974923.1 hypothetical protein -
  FGL89_RS05735 (FGL89_05735) clpE 1143606..1145732 (+) 2127 WP_014974922.1 AAA family ATPase Regulator
  FGL89_RS05740 (FGL89_05740) - 1145828..1146817 (+) 990 WP_041773169.1 nucleoid-associated protein -
  FGL89_RS05745 (FGL89_05745) - 1146932..1147867 (+) 936 WP_014974920.1 DUF1810 family protein -
  FGL89_RS05750 (FGL89_05750) - 1148026..1149963 (+) 1938 WP_186727193.1 C39 family peptidase -

Sequence

Protein


Download         Length: 708 a.a.        Molecular weight: 77600.79 Da        Isoelectric Point: 4.7816

>NTDB_id=331532 FGL89_RS05735 WP_014974922.1 1143606..1145732(+) (clpE) [Leuconostoc carnosum strain CBA3620]
MANNNDLFNDPFGSDMNNIFNNMMGNMNGMNSEKRRYLINGREVTPEEFVKYRQTGQLPQGQGNPAVGNGQQQEAVQQPG
QTKQEGMLAKLGRNLTKEARDGLLDPVIGRNKEIQETAEILGRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPASIK
DKEIYSIDISSLEAGTQFRGAFEENIQNLMKEVKAAGNVILFFDEIHQILGAGSTGGEDGGKGLADIIKPALSRGEISLI
GATTQDEYRNTIMKNAALARRFNEVTVNAPSPKDTLEILKGISKLYEKHHHVELPEDVLKAAVDYAVQYIPQRSLPDKAI
DLLDMTAAHLSAKNPVTDKVSLEKQMTDVKVKQEKAVADEDYEAALKYKNQIADFEKQISGADEATKVIATSNDVAESVE
RLTGIPVAQMGASDIERLKTIGQRLAGKVIGQDEAVNMVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALD
MFGSKENIVRLDMSEYSDLTAVSKLIGTTAGYIGYDDNSNTLTEKVRRNPYSIVLLDEIEKANPQVLTLLLQVMDDGRLT
DGQGNVVNFKNTVIIATSNAGFSDKSEGELMDRLAPYFRPEFLNRFNGVIEFSALSKQDLKQIIDLMLNDVNKTLAKKEL
TLKVSDDVKDHLIEAGYDEALGARPLRRVIEQQIRDQVTDFYLDNPGEKDLQADLVDDKVVISAVVSQ

Nucleotide


Download         Length: 2127 bp        

>NTDB_id=331532 FGL89_RS05735 WP_014974922.1 1143606..1145732(+) (clpE) [Leuconostoc carnosum strain CBA3620]
ATGGCTAACAATAATGATTTGTTCAATGATCCATTTGGATCAGATATGAATAATATTTTTAATAATATGATGGGAAATAT
GAATGGTATGAATTCGGAGAAACGTCGTTACTTAATTAACGGTCGTGAAGTAACCCCGGAAGAATTCGTGAAGTACCGTC
AAACAGGACAGTTACCACAAGGACAAGGTAATCCAGCTGTTGGTAATGGGCAGCAACAAGAAGCAGTACAGCAACCTGGA
CAAACTAAGCAAGAGGGGATGCTGGCAAAGCTAGGTCGTAATTTGACCAAAGAAGCACGTGACGGGTTACTTGATCCAGT
CATTGGCCGTAATAAAGAAATTCAAGAAACTGCTGAAATATTAGGACGTCGTACTAAAAATAACCCAGTACTTGTGGGTG
ATGCCGGGGTTGGTAAGACAGCAGTTGTTGAAGGTTTAGCACAAGCAATTGTTAATGGTGATGTGCCCGCATCAATTAAA
GACAAGGAAATTTATAGTATTGATATTTCTAGTTTGGAAGCAGGCACACAATTCCGTGGCGCTTTTGAAGAAAATATTCA
AAATTTGATGAAAGAGGTTAAAGCTGCAGGAAATGTTATCCTGTTCTTCGATGAAATTCATCAAATATTAGGTGCTGGAT
CAACCGGTGGTGAAGATGGTGGCAAAGGTTTAGCTGATATTATTAAGCCAGCATTGAGCCGTGGTGAGATTTCATTAATT
GGTGCCACAACGCAAGATGAGTATCGTAACACTATCATGAAGAATGCAGCTTTGGCACGTCGTTTCAATGAAGTAACAGT
TAATGCACCTTCACCAAAAGATACACTGGAAATTTTGAAGGGTATTTCAAAACTATATGAGAAGCATCATCATGTAGAAT
TACCGGAAGATGTTTTAAAGGCAGCCGTTGATTATGCCGTGCAATATATTCCACAACGCTCATTGCCTGATAAGGCAATC
GATTTACTTGATATGACGGCTGCACATTTGTCAGCTAAGAATCCAGTGACGGATAAAGTTAGTTTGGAAAAGCAAATGAC
TGATGTGAAAGTAAAGCAAGAAAAAGCCGTTGCTGACGAAGATTATGAAGCAGCGTTGAAGTATAAGAACCAAATTGCAG
ATTTTGAGAAGCAAATATCGGGAGCAGATGAGGCCACTAAGGTTATTGCCACGTCTAACGATGTTGCGGAATCTGTCGAA
CGATTAACTGGTATTCCTGTTGCTCAAATGGGCGCTTCGGATATTGAACGTTTGAAGACAATAGGTCAACGATTAGCAGG
TAAAGTTATTGGACAAGATGAAGCCGTCAATATGGTAGCACGTGCTATACGTCGTAATCGTGCTGGTTTTGATGAAGGTA
ATCGGCCAATTGGTAGTTTCCTATTTGTTGGGCCAACCGGCGTTGGTAAGACGGAGTTAGCTAAACAATTAGCACTTGAT
ATGTTTGGTAGTAAAGAAAATATTGTACGTTTAGATATGTCAGAGTATTCGGATCTCACAGCCGTATCTAAGTTAATTGG
TACAACAGCTGGATATATTGGATATGATGATAACAGTAATACTTTAACAGAGAAAGTTCGTCGTAATCCCTATTCAATTG
TCCTGCTAGATGAAATTGAAAAGGCAAATCCACAAGTATTGACTTTGTTACTACAAGTTATGGATGATGGTCGCTTAACT
GATGGGCAAGGTAATGTGGTTAACTTTAAGAATACCGTGATTATTGCCACATCAAATGCCGGCTTTTCAGATAAGAGTGA
AGGTGAGCTAATGGATCGATTGGCACCATACTTCCGTCCAGAATTCTTGAATCGTTTTAATGGTGTGATTGAATTTTCAG
CATTAAGTAAGCAAGACTTGAAGCAGATTATTGATTTGATGTTAAATGATGTGAATAAGACATTGGCTAAGAAAGAGTTA
ACATTAAAGGTATCTGACGATGTTAAAGATCATTTGATTGAAGCGGGTTACGATGAGGCATTAGGTGCACGACCACTACG
TCGTGTGATTGAGCAACAAATTCGTGATCAAGTAACCGACTTTTATCTAGATAATCCTGGTGAAAAAGACTTACAAGCTG
ATTTAGTTGATGACAAAGTTGTCATTTCAGCAGTCGTTAGTCAGTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(615-686)

AAA domain (Cdc48 subfamily) (AAA_2)

(455-607)

AAA lid domain (AAA_lid_9)

(271-369)

ATPase family associated with various cellular activities (AAA) (AAA)

(130-262)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0DF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

50.077

91.384

0.458
  clpC Lactococcus lactis subsp. cremoris KW2

48.858

92.797

0.453
  clpE Streptococcus pneumoniae D39

49.134

89.689

0.441
  clpE Streptococcus pneumoniae R6

49.134

89.689

0.441
  clpE Streptococcus pneumoniae Rx1

49.134

89.689

0.441
  clpE Streptococcus pneumoniae TIGR4

48.819

89.689

0.438
  clpC Bacillus subtilis subsp. subtilis str. 168

43.75

88.136

0.386
  clpC Streptococcus thermophilus LMD-9

43.402

88.842

0.386
  clpC Streptococcus thermophilus LMG 18311

43.243

88.842

0.384
  clpC Streptococcus pneumoniae Rx1

42.765

87.853

0.376
  clpC Streptococcus pneumoniae D39

42.765

87.853

0.376
  clpC Streptococcus pneumoniae TIGR4

42.605

87.853

0.374
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.581

87.571

0.373
  clpC Streptococcus mutans UA159

42.464

87.147

0.37