Detailed information NTG0033140

Bioinformatically predicted

Overview

• Name: HI0659
• Type: Machinery gene
• Locus tag: SPJ_RS02710
• Genome accession: NC_012466
• Coordinates: 513145..513411 (+)
• Length: 88 a.a.
• NCBI ID: WP_012677043.1
• Uniprot ID: C1CCW1
• Organism: Streptococcus pneumoniae JJA
• Function: DNA uptake (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	512572..513066	513145..513411	flank	79

Gene organization within MGE regions

Location: 512572..513411

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPJ_RS02705 (SPJ_0538)	-	512572..513060 (+)	489	Protein_516	IS30 family transposase	-
SPJ_RS02710 (SPJ_0539)	HI0659	513145..513411 (+)	267	WP_012677043.1	helix-turn-helix transcriptional regulator	Machinery gene

Sequence

Protein

• Length: 88 a.a.
• Molecular weight: 9669.26 Da
• Isoelectric Point: 4.8603

>NTDB_id=33140 SPJ_RS02710 WP_012677043.1 513145..513411(+) (HI0659) [Streptococcus pneumoniae JJA]
MEGCLSELFSKEEILESDMRVAIMSELIEARHEQGISQKKLEELSGVSQPVIARMETGKTSPQLDTVLKVLASLGKILAV
VRLEQGKS

Nucleotide

• Length: 267 bp

>NTDB_id=33140 SPJ_RS02710 WP_012677043.1 513145..513411(+) (HI0659) [Streptococcus pneumoniae JJA]
TTGGAAGGATGTCTATCTGAGCTCTTTAGCAAGGAGGAAATCCTTGAAAGTGATATGCGAGTGGCTATTATGAGCGAGTT
GATTGAAGCTAGACATGAACAAGGAATCAGTCAGAAAAAGCTAGAGGAACTCAGTGGAGTGAGTCAGCCTGTTATAGCTA
GGATGGAGACAGGTAAGACTAGTCCACAGTTGGACACAGTCTTAAAAGTCCTAGCTAGTCTAGGAAAGATACTAGCAGTC
GTCCGACTTGAACAGGGAAAAAGTTGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (28-75)

3D structure

• AlphaFold DB: C1CCW1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
HI0659	Haemophilus influenzae Rd KW20	59.74	87.5	0.523