Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EJN89_RS10885 Genome accession   NZ_CP034441
Coordinates   2123320..2124036 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain PMB 81-4     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2118320..2129036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJN89_RS10865 - 2119412..2120362 (+) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -
  EJN89_RS10870 - 2120511..2121995 (+) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  EJN89_RS10875 - 2121992..2122951 (+) 960 WP_117207349.1 carbohydrate kinase -
  EJN89_RS10880 - 2123139..2123248 (-) 110 Protein_2036 hypothetical protein -
  EJN89_RS10885 agrA 2123320..2124036 (-) 717 WP_000688492.1 LytTR family DNA-binding domain-containing protein Regulator
  EJN89_RS10890 - 2124055..2125347 (-) 1293 WP_070957585.1 GHKL domain-containing protein -
  EJN89_RS10895 - 2125372..2125512 (-) 141 WP_000735197.1 cyclic lactone autoinducer peptide -
  EJN89_RS10900 - 2125516..2126079 (-) 564 WP_001105705.1 accessory gene regulator AgrB -
  EJN89_RS15160 hld 2126369..2126449 (+) 81 WP_000046023.1 delta-hemolysin -
  EJN89_RS10910 - 2127048..2127833 (-) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  EJN89_RS10915 - 2128194..2128820 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=331305 EJN89_RS10885 WP_000688492.1 2123320..2124036(-) (agrA) [Staphylococcus aureus strain PMB 81-4]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=331305 EJN89_RS10885 WP_000688492.1 2123320..2124036(-) (agrA) [Staphylococcus aureus strain PMB 81-4]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment