Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HPPC_RS07425 Genome accession   NC_014555
Coordinates   1540379..1542748 (+) Length   789 a.a.
NCBI ID   WP_000657146.1    Uniprot ID   -
Organism   Helicobacter pylori PeCan4     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1535379..1547748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPPC_RS07390 (HPPC_07660) - 1535579..1536286 (-) 708 WP_001106879.1 Fic family protein -
  HPPC_RS07395 (HPPC_07665) - 1536409..1536828 (-) 420 Protein_1441 CAAX protease -
  HPPC_RS07400 (HPPC_07670) - 1537141..1537920 (+) 780 WP_001209224.1 hypothetical protein -
  HPPC_RS07405 (HPPC_07675) - 1537940..1538233 (+) 294 WP_001160307.1 hypothetical protein -
  HPPC_RS07410 (HPPC_07680) - 1538240..1539766 (+) 1527 WP_000323321.1 hypothetical protein -
  HPPC_RS07415 (HPPC_07685) - 1539763..1540065 (+) 303 WP_001964151.1 hypothetical protein -
  HPPC_RS07420 (HPPC_07690) comB3 1540066..1540332 (+) 267 WP_001173701.1 hypothetical protein Machinery gene
  HPPC_RS07425 (HPPC_07695) comB4 1540379..1542748 (+) 2370 WP_000657146.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPPC_RS07430 (HPPC_07700) - 1542751..1544784 (+) 2034 WP_000655390.1 type IA DNA topoisomerase -
  HPPC_RS07435 (HPPC_07705) - 1544901..1546070 (+) 1170 WP_000044722.1 type IV secretion system protein -
  HPPC_RS07440 (HPPC_07710) - 1546070..1547587 (+) 1518 WP_000714765.1 TrbG/VirB9 family P-type conjugative transfer protein -

Sequence

Protein


Download         Length: 789 a.a.        Molecular weight: 91249.81 Da        Isoelectric Point: 7.9595

>NTDB_id=33082 HPPC_RS07425 WP_000657146.1 1540379..1542748(+) (comB4) [Helicobacter pylori PeCan4]
MKEETNIVGIYNEHYLLSEKSNLVGALKLEGISYLSLDDKEIAQKFNERILALNEIVDGVHFKIVAKRRNIFMHQEYTQE
EISNPFALEVINLWEQGIEDVYQNFYYLIFETKNDSIKGYLERFKKKITTNELENIQENDKQDEVKYQENYFIGFDNFNL
ADKSKILDSIINNVKNMLSGLFVEKLDANSLLNFYAEYINGVSSEYTFSRGRLLDGMINSDVHFKKDFFTHIHNGKEIFK
RFISIKTYDIDKIVSIALSSVLHLSLEFDVILNIDNIPKTKAEKRIETKRKRANKSVRVEIDELNDMVKTGRVLMQEISL
NILVHAKTKTDLDNACIEITNLLKQKGIVSTQESIGMLPMFFSFFPNRNRLNFRKRLLSSQNIASLIVLEKQNCGFSRNS
WGNRHLTIFRNQDKSPYLFNFHAYEAKRRDDMVLGHTIIFGGTGAGKTTLIEFLITNCFKYKDLSILALDRNNGMRVMTE
FLDGQYNDSNDFYINPFSLKNTSANCTFLVSWLAFMLNIDEDTKDEKEKKTLSALSKTIRVCYNNITKQGGAIFKLRDFK
DTLERDYLDSKDILEKESLKDLYKHSTDCLDFAKKLSVIDMDALSSNKKDFNLAVLYLFYKVMNRAKLENKPFYIFIDEA
KSVIENPIMLAKIKDTLAQARKLNGVLTLAFQDINQLDGIEGAKSIIENAAQVILYPTNNFEKLESYGILLSPIEKSFLN
KTPLNARQILVKNLLTQSSVFLEINLEKLNSTNKKFLRAYSSSASSVFELEMLKKDNPKDYKEIYLTKE

Nucleotide


Download         Length: 2370 bp        

>NTDB_id=33082 HPPC_RS07425 WP_000657146.1 1540379..1542748(+) (comB4) [Helicobacter pylori PeCan4]
ATGAAAGAAGAAACTAACATTGTGGGCATTTACAATGAGCATTATCTTTTAAGTGAAAAATCAAATCTTGTAGGCGCTCT
TAAGTTAGAGGGAATTTCTTATTTATCTTTAGATGACAAAGAAATAGCGCAAAAATTTAATGAACGCATTTTAGCTCTTA
ATGAGATTGTAGATGGAGTGCATTTTAAAATCGTAGCTAAAAGGCGTAATATTTTCATGCACCAAGAATATACTCAAGAA
GAGATAAGTAATCCTTTTGCATTAGAAGTTATCAATTTGTGGGAACAAGGGATTGAGGATGTCTATCAAAATTTCTATTA
CTTAATTTTTGAAACCAAGAATGATAGCATTAAAGGTTATTTGGAACGATTTAAGAAAAAAATCACTACCAATGAATTAG
AAAATATTCAAGAAAATGATAAACAAGATGAAGTGAAATATCAAGAAAACTATTTCATAGGCTTTGATAATTTTAATTTA
GCAGATAAATCTAAAATATTAGACAGCATTATCAATAATGTTAAAAATATGCTTTCTGGTTTGTTTGTAGAAAAATTAGA
CGCCAATAGTTTGCTTAATTTTTATGCGGAATACATTAATGGCGTTTCTAGTGAATACACTTTTTCTAGAGGTCGTTTGC
TTGATGGCATGATCAATTCTGATGTGCATTTTAAAAAAGATTTTTTCACTCACATTCACAATGGTAAAGAGATTTTCAAG
CGTTTCATCAGCATTAAGACTTATGATATAGACAAAATTGTCAGCATCGCTCTTTCTTCAGTGTTGCATTTATCTTTAGA
ATTTGATGTGATTTTAAACATTGACAATATTCCTAAAACAAAGGCTGAAAAAAGGATTGAAACTAAAAGAAAAAGAGCGA
ATAAGAGCGTTAGAGTTGAAATTGATGAATTGAATGACATGGTTAAAACAGGCAGGGTTTTAATGCAAGAGATTTCTTTA
AACATTCTAGTTCATGCCAAAACTAAAACCGATTTAGATAATGCTTGTATAGAAATTACCAACTTGCTTAAACAAAAAGG
TATTGTAAGCACGCAAGAAAGTATTGGCATGTTGCCTATGTTTTTTAGCTTCTTCCCCAATCGTAATCGCTTGAATTTTA
GAAAGCGTTTGTTGTCTAGTCAAAATATTGCTTCTTTAATCGTATTAGAAAAACAAAATTGTGGTTTTTCTAGAAATTCA
TGGGGTAATCGCCATTTAACTATTTTTAGAAACCAAGACAAATCGCCTTATTTATTCAATTTCCATGCTTATGAGGCAAA
AAGAAGAGATGATATGGTATTAGGGCATACCATCATCTTTGGTGGCACAGGGGCTGGTAAAACCACTTTAATTGAGTTTT
TAATCACTAATTGTTTTAAGTATAAAGATTTAAGTATTTTGGCTTTAGACAGAAATAATGGCATGCGTGTGATGACTGAG
TTTTTAGATGGTCAATACAACGATAGCAATGATTTTTATATTAATCCATTTTCTTTAAAAAATACAAGCGCTAATTGCAC
CTTTTTGGTGAGTTGGTTGGCGTTCATGCTCAATATTGATGAAGATACTAAAGATGAAAAAGAAAAAAAGACCTTAAGTG
CCTTGTCTAAAACGATCAGAGTTTGCTATAACAATATCACAAAACAAGGTGGCGCTATTTTTAAGTTAAGAGATTTTAAA
GACACGCTAGAAAGAGACTATTTAGATAGCAAAGACATTTTAGAGAAAGAGAGCTTAAAAGACTTATACAAGCATTCTAC
TGATTGTTTAGACTTTGCCAAAAAGCTTTCTGTTATTGATATGGACGCTCTTTCTAGTAATAAAAAAGATTTTAACTTGG
CAGTGTTATATCTATTCTATAAAGTCATGAATAGAGCTAAATTAGAAAATAAGCCTTTTTATATCTTCATTGATGAAGCA
AAATCTGTTATTGAAAATCCCATCATGTTAGCTAAAATCAAAGACACACTCGCTCAAGCTAGAAAACTCAATGGGGTTTT
AACTTTAGCTTTTCAAGACATTAACCAACTTGATGGCATAGAGGGAGCAAAGTCCATTATAGAAAACGCCGCTCAAGTCA
TACTCTATCCTACAAACAATTTTGAGAAATTAGAAAGCTATGGCATTTTATTAAGCCCTATTGAAAAATCCTTTTTAAAC
AAAACGCCGTTAAACGCTAGGCAAATATTAGTGAAAAACCTTCTTACTCAATCTAGCGTATTTTTAGAAATCAATTTAGA
AAAATTAAACAGCACCAATAAAAAATTTTTAAGAGCGTATAGCTCTAGCGCGTCTAGCGTTTTTGAACTAGAGATGCTTA
AAAAGGATAATCCAAAAGATTACAAAGAAATTTATCTGACAAAGGAGTAG

Domains

Predicted by InterProScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-374)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

36.146

100

0.364

Multiple sequence alignment