Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   D8X56_RS04290 Genome accession   NZ_CP034314
Coordinates   883714..885498 (+) Length   594 a.a.
NCBI ID   WP_125302455.1    Uniprot ID   -
Organism   Helicobacter pylori strain HP42K     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 878714..890498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D8X56_RS04260 (D8X56_04260) motB 879488..880255 (+) 768 WP_125302448.1 flagellar motor protein MotB -
  D8X56_RS04265 (D8X56_04265) - 880259..880696 (+) 438 WP_001031790.1 hypothetical protein -
  D8X56_RS04270 (D8X56_04270) - 880765..882426 (+) 1662 WP_125302450.1 glycine betaine ABC transporter substrate-binding protein -
  D8X56_RS04275 (D8X56_04275) - 882428..883069 (+) 642 WP_125302453.1 ATP-binding cassette domain-containing protein -
  D8X56_RS04280 (D8X56_04280) - 883081..883260 (-) 180 WP_000468799.1 hypothetical protein -
  D8X56_RS04285 (D8X56_04285) - 883252..883713 (+) 462 WP_108311046.1 hypothetical protein -
  D8X56_RS04290 (D8X56_04290) uvrC 883714..885498 (+) 1785 WP_125302455.1 excinuclease ABC subunit UvrC Machinery gene
  D8X56_RS04295 (D8X56_04295) - 885509..886774 (+) 1266 WP_125302458.1 homoserine dehydrogenase -
  D8X56_RS04300 (D8X56_04300) - 886774..887118 (+) 345 WP_014534392.1 YraN family protein -
  D8X56_RS04305 (D8X56_04305) trxA 887207..887527 (+) 321 WP_000020210.1 thioredoxin -
  D8X56_RS04310 (D8X56_04310) trxB 887532..888467 (+) 936 WP_079372973.1 thioredoxin-disulfide reductase -
  D8X56_RS04315 (D8X56_04315) - 888824..889645 (+) 822 WP_125302461.1 glycosyltransferase family 25 protein -
  D8X56_RS04320 (D8X56_04320) - 889856..890104 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68678.02 Da        Isoelectric Point: 9.7879

>NTDB_id=330635 D8X56_RS04290 WP_125302455.1 883714..885498(+) (uvrC) [Helicobacter pylori strain HP42K]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKKCLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGTSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLN
ACSNEALKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDV
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSDEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=330635 D8X56_RS04290 WP_125302455.1 883714..885498(+) (uvrC) [Helicobacter pylori strain HP42K]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCGAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACGATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCATTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAAAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGCAATTTGCGTTTTGAAGAAGCCCTCATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCACAAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCTGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTAATACCAGAACAGATTTTATTGAAC
GCTTGCTCTAACGAAGCGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAACGCCTTCCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTGATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

98.316

100

0.983

Multiple sequence alignment