Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EI285_RS03230 Genome accession   NZ_CP034309
Coordinates   598253..600115 (-) Length   620 a.a.
NCBI ID   WP_125296345.1    Uniprot ID   -
Organism   Aliarcobacter skirrowii strain A2S6     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 593253..605115
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EI285_RS03215 (EI285_03215) - 593495..594670 (-) 1176 WP_125296342.1 MalY/PatB family protein -
  EI285_RS03220 (EI285_03220) - 594895..597171 (-) 2277 WP_125296343.1 methyl-accepting chemotaxis protein -
  EI285_RS03225 (EI285_03225) - 597250..598281 (-) 1032 WP_125296344.1 alanine racemase -
  EI285_RS03230 (EI285_03230) uvrC 598253..600115 (-) 1863 WP_125296345.1 excinuclease ABC subunit UvrC Machinery gene
  EI285_RS09945 (EI285_03235) - 600151..601818 (-) 1668 WP_125296346.1 efflux RND transporter permease subunit -
  EI285_RS09950 (EI285_03240) - 601815..603374 (-) 1560 WP_125296347.1 efflux RND transporter permease subunit -
  EI285_RS03245 (EI285_03245) - 603367..604089 (-) 723 WP_066161619.1 efflux RND transporter periplasmic adaptor subunit -

Sequence

Protein


Download         Length: 620 a.a.        Molecular weight: 71909.04 Da        Isoelectric Point: 9.4579

>NTDB_id=330613 EI285_RS03230 WP_125296345.1 598253..600115(-) (uvrC) [Aliarcobacter skirrowii strain A2S6]
MNLEEKLKQLPNEAGVYQYFDNQGHLLYIGKAKSLKNRVKSYFKFSPTLQASSDLSPRIYKMISETSSLEWIVVPNEHDA
LILENSLIKQLKPKYNVLLRDDKTYPYIFVNLNEDFPRLEITRKIEKGKNIKYFGPYSSGAKDMLDSIYEIVPLVQKKSC
VKGKKACLFFQIGKCLAPCEDKISKEDYKKILDDALSYIYNKSKILTKLKEKMLFYSQNFRFEEALVLRDRIKTIEKSQI
KTGIDLTSNDDLDIFAIKSSNKKAVIVRMFIRDGKLASSNYDFMKSNDDVEFDIQEAYKRAIINYYSNDLPIIPKEILVA
NEIEELDSIEDFLYQKFSKKIKIVNPKIDKKATIVKIALNNCDELLRLESIKQQNSIYSEIKELFSLKNSPNIIESFDNS
HLMGQARVGAMVVWNSQIESFDKKSYRHYNLESLDEYSQMRELLMRRVESFDKNSPPDLWLIDGGSTLLNLAFEIVSSIG
VNLDIIAISKQKVDAKAYRAKGNAKDILHFIENKEIKSINLLPSDKRLQFVQRLRDEAHRFAISFHKKQKRKEDKDISFL
QIKGIGEAKIKKLLLYFGEFEKIKNATFDELKTVLNQSDAQNIVDYFKKEKSGEDINKQG

Nucleotide


Download         Length: 1863 bp        

>NTDB_id=330613 EI285_RS03230 WP_125296345.1 598253..600115(-) (uvrC) [Aliarcobacter skirrowii strain A2S6]
ATGAATTTAGAAGAGAAATTAAAGCAACTCCCAAATGAAGCTGGAGTTTATCAATATTTTGATAATCAAGGGCATCTATT
ATATATAGGAAAAGCAAAAAGCTTAAAAAATAGAGTAAAAAGCTACTTTAAATTTAGCCCTACTCTACAAGCTTCAAGCG
ATTTAAGTCCACGAATTTATAAGATGATTAGTGAAACATCCTCTTTAGAGTGGATTGTTGTACCAAATGAGCACGATGCT
TTAATTTTAGAAAACTCCTTAATAAAACAGCTAAAACCAAAATACAATGTACTTTTAAGAGATGATAAAACATATCCATA
TATTTTTGTAAATTTAAATGAGGATTTTCCACGACTTGAAATTACAAGAAAAATAGAAAAAGGTAAAAATATAAAATATT
TTGGTCCATATTCAAGTGGAGCAAAAGATATGCTTGATAGTATCTATGAGATAGTTCCCTTGGTGCAAAAAAAATCTTGT
GTAAAGGGTAAAAAAGCTTGTCTATTTTTTCAAATAGGTAAATGTTTAGCTCCATGTGAAGATAAAATCTCTAAAGAGGA
TTATAAAAAGATTTTAGATGATGCTTTAAGTTATATCTACAATAAATCAAAAATTTTAACAAAATTAAAAGAGAAGATGC
TTTTTTATTCACAAAACTTTAGATTTGAAGAGGCACTTGTATTAAGAGATAGAATAAAAACTATTGAAAAATCGCAAATT
AAAACAGGAATTGATTTAACATCAAATGATGATTTAGATATTTTTGCAATAAAATCTAGCAACAAAAAAGCTGTAATTGT
AAGAATGTTTATAAGAGATGGAAAATTAGCATCTTCAAACTATGATTTTATGAAATCAAATGATGATGTTGAGTTTGATA
TACAAGAGGCTTATAAAAGAGCTATTATAAACTACTACTCAAATGATTTACCAATTATTCCAAAAGAGATACTTGTAGCA
AATGAGATTGAAGAGCTTGACTCTATAGAAGATTTTTTATATCAAAAATTTAGTAAAAAGATAAAAATAGTAAATCCAAA
AATAGATAAAAAAGCTACTATTGTAAAAATTGCTTTAAATAACTGTGATGAGCTTTTAAGATTGGAGAGTATTAAACAGC
AAAACTCTATTTATAGTGAAATAAAAGAGCTATTCTCTTTAAAAAATAGTCCAAACATAATAGAGAGTTTTGATAACTCC
CATTTAATGGGACAAGCAAGAGTTGGAGCTATGGTTGTTTGGAATAGCCAAATAGAGAGTTTTGATAAAAAATCATATAG
ACACTACAATCTTGAATCACTTGATGAATACTCACAAATGAGAGAACTTCTTATGCGAAGAGTTGAGAGTTTTGATAAAA
ACTCTCCTCCTGATTTATGGCTTATTGATGGTGGTTCAACTTTGCTAAATTTAGCTTTTGAGATAGTTTCTTCTATTGGG
GTAAATTTAGATATTATTGCCATTTCAAAACAAAAAGTAGATGCAAAAGCCTATAGAGCCAAAGGAAATGCAAAAGATAT
TTTGCACTTTATTGAAAATAAAGAGATAAAAAGTATAAATCTTCTTCCAAGTGATAAAAGATTGCAATTTGTTCAAAGAT
TAAGAGATGAAGCTCATAGATTTGCTATTAGTTTTCATAAAAAACAGAAAAGAAAAGAGGACAAAGATATCTCTTTTCTT
CAAATAAAGGGTATTGGTGAAGCAAAAATCAAAAAACTACTTCTATATTTTGGAGAGTTTGAAAAGATAAAAAATGCAAC
ATTTGATGAGTTAAAAACTGTTTTAAATCAAAGTGATGCACAAAATATAGTTGATTATTTTAAAAAGGAAAAAAGTGGCG
AAGATATTAATAAACAAGGATAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(382-543)

UvrB/uvrC motif (UVR)

(204-237)

GIY-YIG catalytic domain (GIY-YIG)

(14-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.167

96.774

0.495

Multiple sequence alignment