Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SCA_RS07850 Genome accession   NC_012121
Coordinates   1564339..1565055 (+) Length   238 a.a.
NCBI ID   WP_015900794.1    Uniprot ID   B9DMK5
Organism   Staphylococcus carnosus subsp. carnosus TM300     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1559339..1570055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCA_RS07825 (SCA_1544) - 1560595..1561395 (+) 801 WP_015900789.1 carbon-nitrogen family hydrolase -
  SCA_RS13200 - 1561708..1561788 (-) 81 WP_041612998.1 delta-lysin family phenol-soluble modulin -
  SCA_RS07835 (SCA_1545) - 1562286..1562861 (+) 576 WP_015900790.1 accessory gene regulator AgrB -
  SCA_RS07840 (SCA_1546) agrD 1562870..1563007 (+) 138 WP_015900791.1 cyclic lactone autoinducer peptide AgrD -
  SCA_RS07845 agrC 1563039..1564334 (+) 1296 Protein_1532 quorum-sensing sensor histidine kinase AgrC -
  SCA_RS07850 (SCA_1549) agrA 1564339..1565055 (+) 717 WP_015900794.1 quorum-sensing response regulator AgrA Regulator
  SCA_RS07855 (SCA_1550) - 1565102..1566574 (-) 1473 WP_015900795.1 GH32 C-terminal domain-containing protein -
  SCA_RS07860 (SCA_1551) - 1566786..1567871 (+) 1086 WP_015900796.1 YeeE/YedE family protein -
  SCA_RS07865 (SCA_1552) - 1567898..1568122 (+) 225 WP_015900797.1 sulfurtransferase TusA family protein -
  SCA_RS07870 (SCA_1553) - 1568172..1568816 (-) 645 WP_015900798.1 redox-sensing transcriptional repressor Rex -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27830.62 Da        Isoelectric Point: 4.6988

>NTDB_id=33036 SCA_RS07850 WP_015900794.1 1564339..1565055(+) (agrA) [Staphylococcus carnosus subsp. carnosus TM300]
MKIIICEDDQQQRAHIEEIINNYTMIEEKPLEIALSTNDPYEVIEYAKNTNDICCYFLDIQLDADINGIKLGSELRKFDT
VGNIVFVTSYSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESNVETIELKRGSNSVYVNYDDVM
FFESSTKSHRLIAHLDNRQIEFYGSLKELSNIDERFFRCHNSFVINLNNIEEVISKEREIHFKNGEHCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=33036 SCA_RS07850 WP_015900794.1 1564339..1565055(+) (agrA) [Staphylococcus carnosus subsp. carnosus TM300]
ATGAAAATTATTATTTGTGAAGACGACCAGCAACAACGCGCACATATCGAAGAAATTATCAATAACTATACAATGATTGA
AGAAAAGCCATTAGAAATTGCTCTCTCAACTAATGATCCATATGAAGTAATTGAATACGCTAAAAATACAAATGACATTT
GTTGTTACTTCTTAGATATTCAACTTGACGCAGATATAAATGGGATTAAACTCGGTAGTGAGTTACGTAAATTTGATACG
GTTGGGAATATTGTTTTTGTGACAAGTTATAGCGAATTGACTTACTTAACTTTTGTTTATAAAGTAGCAGCAATGGATTT
TATCTTTAAAGATGATCCTAGCGAAATGAAATCACGGATTATTGATTGCATTGAAACAGCACTTACACGTTTGCAGCTAT
TATCTAAAGAAAGCAACGTTGAAACAATCGAACTTAAAAGAGGCAGTAATTCTGTCTATGTTAATTACGATGATGTAATG
TTTTTCGAATCATCCACTAAATCTCATAGATTGATTGCACATTTAGATAATCGTCAAATTGAGTTTTATGGAAGTTTGAA
AGAACTCAGTAATATTGATGAACGCTTCTTCCGTTGTCACAACAGCTTTGTAATCAACCTCAATAATATCGAAGAAGTGA
TTTCAAAAGAACGTGAAATTCACTTTAAAAACGGCGAACATTGCTATGTCTCTGTCCGTAACCTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DMK5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

78.151

100

0.782

Multiple sequence alignment