Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   NAMH_RS04910 Genome accession   NC_012115
Coordinates   912712..914547 (+) Length   611 a.a.
NCBI ID   WP_012663974.1    Uniprot ID   B9L9T8
Organism   Nautilia profundicola AmH     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 907712..919547
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NAMH_RS04890 (NAMH_0991) - 907881..908405 (-) 525 WP_012663590.1 2-oxoacid:acceptor oxidoreductase family protein -
  NAMH_RS04895 (NAMH_0992) - 908468..910270 (-) 1803 WP_015902677.1 thiamine pyrophosphate-dependent enzyme -
  NAMH_RS09175 (NAMH_0993) - 910384..910557 (+) 174 WP_012663577.1 symporter small accessory protein -
  NAMH_RS04900 (NAMH_0994) - 910554..912197 (+) 1644 WP_015902218.1 sodium:solute symporter family protein -
  NAMH_RS04905 (NAMH_0995) - 912243..912503 (+) 261 WP_012663793.1 hypothetical protein -
  NAMH_RS04910 (NAMH_0996) uvrC 912712..914547 (+) 1836 WP_012663974.1 excinuclease ABC subunit UvrC Machinery gene
  NAMH_RS04915 (NAMH_0997) - 914544..915047 (+) 504 WP_015902633.1 YbhB/YbcL family Raf kinase inhibitor-like protein -
  NAMH_RS04920 (NAMH_0998) - 915155..915412 (+) 258 Protein_958 putative metalloprotease CJM1_0395 family protein -
  NAMH_RS04925 (NAMH_0999) - 915508..916275 (+) 768 WP_012663631.1 bifunctional riboflavin kinase/FAD synthetase -
  NAMH_RS04930 (NAMH_1000) - 916276..916824 (-) 549 WP_012664009.1 SiaB family protein kinase -
  NAMH_RS04935 (NAMH_1001) - 916817..917206 (-) 390 WP_015902841.1 DUF1987 domain-containing protein -
  NAMH_RS04940 (NAMH_1002) - 917207..918571 (-) 1365 WP_015901778.1 HD-GYP domain-containing protein -

Sequence

Protein


Download         Length: 611 a.a.        Molecular weight: 70537.66 Da        Isoelectric Point: 9.7080

>NTDB_id=33007 NAMH_RS04910 WP_012663974.1 912712..914547(+) (uvrC) [Nautilia profundicola AmH]
MSFSEKIKSLPDQPGIYQYFDENGKLLYIGKAKSLKKRVKSYFRFNPFRPADNLSPRIYKMISEAKDLNYIVVESENDAL
ILENSLIKQLKPKYNILLRDDKTYPYIYIDLDEPFPMPQITRKVVKGKNIKYFGPFSSGASAILKTIYEEIPLVQSKSCL
RSGKACLYHQIGRCLAPCEGKVTSREYMKYVDQAIELIHDKEKILEILNQKMQKYAENLQFEEAAEIRDRIKSIESAEIY
SHVDLAKLEDLDIFAVEIFNKKAVVIRIFVRQGKVVASSNSVINSQTVPEIGEIYTRAILEFYSTETPFTSSKILVGDDF
EEREWLSQVLSEKFGKKISIITPTTKERKSLIKLAKLNALEVIKNQKENTVLDELKILFNLQNTPYKIEVFDTSHMQGEA
TVGAMVVWEDGKFKKSDYRHYHLEGKDEYSQMRELLTRRAQSFEKSPPPDLWLIDGGKAQLNLAKEIIDSTGANIDVLAI
SKEKIDAKAHRAKGKAKDKIYFINEKLKVKSEKLNIDKLELSQSDKRLQFLQMLRDEAHRFAIEFHRKTKRKKDTQIDLL
QVKGIGKAKMTKLLNYFGSFDNIKKASFDELKDVLNEKDAKAIKEFFKGQK

Nucleotide


Download         Length: 1836 bp        

>NTDB_id=33007 NAMH_RS04910 WP_012663974.1 912712..914547(+) (uvrC) [Nautilia profundicola AmH]
TTGTCGTTTAGTGAAAAAATAAAATCCCTACCCGATCAGCCCGGAATTTATCAGTATTTTGACGAAAACGGGAAACTTCT
GTATATCGGAAAGGCGAAAAGCCTTAAAAAACGTGTAAAAAGCTATTTTCGTTTTAATCCTTTCAGACCTGCGGATAATC
TGTCTCCAAGAATTTACAAAATGATAAGCGAGGCAAAAGATCTAAATTATATCGTGGTAGAAAGCGAAAACGACGCGCTT
ATACTTGAAAACTCTCTAATCAAACAGCTTAAACCCAAATACAATATATTACTTCGTGATGACAAAACGTACCCGTATAT
TTATATAGATCTTGACGAACCGTTTCCGATGCCGCAGATTACCCGCAAAGTCGTTAAGGGAAAAAATATCAAATATTTCG
GACCGTTTAGCAGCGGTGCGTCTGCAATTCTTAAAACAATATACGAAGAAATACCTCTTGTTCAGTCCAAATCATGTCTT
AGAAGCGGTAAGGCGTGCCTGTATCATCAGATAGGAAGATGTTTGGCCCCGTGTGAGGGCAAAGTTACAAGCCGCGAATA
TATGAAATATGTCGATCAGGCTATAGAACTTATACACGACAAAGAAAAAATACTTGAAATACTAAACCAAAAAATGCAAA
AATACGCCGAAAACCTGCAGTTTGAAGAAGCGGCGGAAATAAGGGACAGGATCAAATCGATAGAGAGTGCGGAGATTTAT
TCCCATGTGGATCTGGCAAAACTGGAAGATTTGGATATATTTGCCGTTGAAATATTCAATAAAAAAGCGGTTGTTATAAG
AATATTCGTACGTCAGGGAAAAGTGGTAGCCAGCAGCAATTCGGTAATCAACTCCCAGACAGTCCCTGAAATAGGAGAAA
TATACACAAGGGCGATACTTGAATTTTATTCTACAGAGACGCCTTTTACCTCAAGTAAGATTTTAGTTGGTGACGACTTT
GAAGAAAGGGAGTGGCTAAGCCAGGTGTTAAGCGAAAAATTTGGCAAAAAGATAAGCATAATAACCCCTACCACCAAAGA
GAGAAAAAGCCTTATCAAACTTGCCAAACTAAATGCTCTTGAAGTTATCAAAAACCAAAAAGAAAACACCGTTTTGGATG
AGCTGAAAATTCTCTTCAATCTCCAAAACACACCTTATAAAATAGAAGTCTTCGACACATCGCACATGCAGGGTGAGGCG
ACGGTCGGAGCGATGGTCGTATGGGAAGACGGAAAGTTTAAAAAGTCTGACTACAGACACTACCATCTTGAAGGAAAAGA
CGAATATTCCCAAATGAGAGAGCTTCTTACAAGAAGGGCGCAGAGTTTTGAAAAATCCCCTCCTCCCGACCTGTGGCTCA
TAGACGGCGGTAAAGCGCAGTTGAATCTGGCAAAAGAGATTATTGATTCAACCGGAGCCAACATAGACGTACTTGCGATA
TCCAAAGAAAAAATCGACGCCAAAGCTCACAGGGCGAAAGGTAAGGCGAAGGATAAAATATATTTTATCAATGAAAAGTT
AAAAGTGAAAAGTGAAAAATTAAATATTGACAAACTTGAACTAAGTCAGAGCGATAAGAGACTGCAGTTTTTACAGATGT
TAAGGGATGAAGCACACAGGTTCGCCATAGAATTCCACAGAAAAACAAAACGCAAAAAAGACACCCAAATAGATCTTTTA
CAGGTAAAAGGTATCGGAAAGGCTAAAATGACAAAACTTTTGAATTATTTCGGAAGTTTTGATAATATAAAAAAAGCCTC
TTTTGATGAGCTTAAAGATGTTTTAAACGAAAAAGACGCAAAAGCCATAAAGGAATTTTTCAAAGGGCAAAAATGA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(378-543)

UvrB/uvrC motif (UVR)

(203-236)

GIY-YIG catalytic domain (GIY-YIG)

(14-95)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9L9T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

49.498

97.872

0.484

Multiple sequence alignment