Detailed information NTG0329653

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: BVMH_RS17990
• Genome accession: NZ_CP034176
• Coordinates: 3587514..3588677 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain MH25
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3582514..3593677

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BVMH_RS17960 (BVMH_17960)	-	3582778..3583197 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
BVMH_RS17965 (BVMH_17965)	comFC	3583271..3583960 (-)	690	WP_197200179.1	double zinc ribbon domain-containing protein	Machinery gene
BVMH_RS17970 (BVMH_17970)	-	3583966..3584250 (-)	285	WP_007407481.1	competence protein ComFB	-
BVMH_RS17975 (BVMH_17975)	comFA	3584308..3585693 (-)	1386	WP_099320008.1	DEAD/DEAH box helicase	Machinery gene
BVMH_RS17980 (BVMH_17980)	-	3585802..3586650 (-)	849	WP_094031329.1	DegV family protein	-
BVMH_RS17985 (BVMH_17985)	degU	3586748..3587437 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
BVMH_RS17990 (BVMH_17990)	degS	3587514..3588677 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
BVMH_RS17995 (BVMH_17995)	-	3588900..3589547 (+)	648	WP_007407485.1	YigZ family protein	-
BVMH_RS18000 (BVMH_18000)	-	3589552..3590787 (+)	1236	WP_025285355.1	LCP family protein	-
BVMH_RS18005 (BVMH_18005)	-	3590886..3591962 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
BVMH_RS18010 (BVMH_18010)	-	3592095..3593291 (-)	1197	WP_094031330.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=329653 BVMH_RS17990 WP_007407484.1 3587514..3588677(-) (degS) [Bacillus velezensis strain MH25]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=329653 BVMH_RS17990 WP_007407484.1 3587514..3588677(-) (degS) [Bacillus velezensis strain MH25]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951