Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EAL91_RS05450 Genome accession   NZ_CP034147
Coordinates   1101655..1103439 (-) Length   594 a.a.
NCBI ID   WP_121053490.1    Uniprot ID   -
Organism   Helicobacter pylori strain HP14039     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1096655..1108439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EAL91_RS05420 - 1097027..1097275 (+) 249 WP_000790557.1 RNA-binding protein -
  EAL91_RS05425 - 1097490..1098311 (-) 822 WP_121054751.1 glycosyltransferase family 25 protein -
  EAL91_RS05430 trxB 1098684..1099619 (-) 936 WP_121053486.1 thioredoxin-disulfide reductase -
  EAL91_RS05435 trxA 1099625..1099945 (-) 321 WP_000020205.1 thioredoxin -
  EAL91_RS05440 - 1100034..1100378 (-) 345 WP_121053488.1 YraN family protein -
  EAL91_RS05445 - 1100379..1101644 (-) 1266 WP_039087351.1 homoserine dehydrogenase -
  EAL91_RS05450 uvrC 1101655..1103439 (-) 1785 WP_121053490.1 excinuclease ABC subunit UvrC Machinery gene
  EAL91_RS05455 - 1103440..1103901 (-) 462 WP_121053492.1 hypothetical protein -
  EAL91_RS05460 - 1103893..1104072 (+) 180 WP_000468791.1 hypothetical protein -
  EAL91_RS05465 - 1104084..1104725 (-) 642 WP_121053494.1 ATP-binding cassette domain-containing protein -
  EAL91_RS05470 - 1104727..1106389 (-) 1663 Protein_1029 ABC transporter permease/substrate-binding protein -
  EAL91_RS05480 - 1106458..1106895 (-) 438 WP_164997406.1 hypothetical protein -
  EAL91_RS05485 motB 1106901..1107674 (-) 774 WP_001085350.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68673.96 Da        Isoelectric Point: 9.6284

>NTDB_id=329357 EAL91_RS05450 WP_121053490.1 1101655..1103439(-) (uvrC) [Helicobacter pylori strain HP14039]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEITPNHRASLRVQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNEVLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSDEDLILEEMRSLFNLECVPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTINNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=329357 EAL91_RS05450 WP_121053490.1 1101655..1103439(-) (uvrC) [Helicobacter pylori strain HP14039]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAACAGCAGTGGCGTGTATCAATACTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCATAATAATGAAATCACGCCCA
ACCATCGCGCAAGCTTACGCGTCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGACTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGCAAAGCCCCATGCGAGGATAAAATCACTAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAGATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
CTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CTGATGAGGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAGC
GCTTGCTCTAATGAGGTGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAACATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTG
ATGAAGATCTGATTTTAGAAGAGATGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCACGCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTTCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGTAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGATAAACAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAACAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968

Multiple sequence alignment