Detailed information NTG0032934

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SUB_RS06565
• Genome accession: NC_012004
• Coordinates: 1300874..1301917 (-)
• Length: 347 a.a.
• NCBI ID: WP_015911639.1
• Uniprot ID: B9DUX6
• Organism: Streptococcus uberis 0140J
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1295874..1306917

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SUB_RS06540 (SUB1308)	-	1295946..1296893 (-)	948	WP_015911634.1	ABC transporter permease subunit	-
SUB_RS06545 (SUB1309)	-	1296895..1298373 (-)	1479	WP_015911635.1	sugar ABC transporter ATP-binding protein	-
SUB_RS06550 (SUB1310)	rbsD	1298388..1298786 (-)	399	WP_015911636.1	D-ribose pyranase	-
SUB_RS06555 (SUB1311)	rbsK	1298761..1299672 (-)	912	WP_015911637.1	ribokinase	-
SUB_RS06560 (SUB1312)	-	1299669..1300649 (-)	981	WP_041817655.1	LacI family DNA-binding transcriptional regulator	-
SUB_RS06565 (SUB1313)	sepM	1300874..1301917 (-)	1044	WP_015911639.1	SepM family pheromone-processing serine protease	Regulator
SUB_RS06570 (SUB1314)	coaD	1301895..1302395 (-)	501	WP_015911640.1	pantetheine-phosphate adenylyltransferase	-
SUB_RS06575 (SUB1315)	rsmD	1302385..1302924 (-)	540	WP_015911641.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SUB_RS06580 (SUB1316)	aguB	1303013..1303888 (-)	876	WP_015911642.1	N-carbamoylputrescine amidase	-
SUB_RS06585 (SUB1317)	aguA	1303885..1304985 (-)	1101	WP_015911643.1	agmatine deiminase	-
SUB_RS06590 (SUB1318)	nspC	1305001..1306128 (-)	1128	WP_015911644.1	carboxynorspermidine decarboxylase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38210.89 Da
• Isoelectric Point: 9.5719

>NTDB_id=32934 SUB_RS06565 WP_015911639.1 1300874..1301917(-) (sepM) [Streptococcus uberis 0140J]
MKVIKTYKWWVLSILSMVLILFALFFPLPYYIEMPGGAYDIRSVLKVNGKKDNEKGSYNFVAVTVSHATFAQMLYAWMTP
FTEISSAEDTTGGYSDADYLRINQFYMETSQNGAIYQALKLADKDVSLDYLGVYVLDVSKDSTFKGKLNIADTVTAVNHK
SFKSSKELIDYVSGLKLGDKVSVQFTSDGKDKSKNGKIIKLKNGKNGIGIGLTDHTKVHTDQDIVFSTDGVGGPSAGLMF
TLDILDQINKEDLRKGRKIAGTGTIDQDGRVGDIGGAGLKVVAAANEGAEIFFVPNNPVDKKLKKRYPDLKTNYDEAKEA
AKQIKTKMKIVPVTTAKEAIDYLKKTN

Nucleotide

• Length: 1044 bp

>NTDB_id=32934 SUB_RS06565 WP_015911639.1 1300874..1301917(-) (sepM) [Streptococcus uberis 0140J]
ATGAAAGTAATCAAAACTTATAAATGGTGGGTGCTCTCCATCTTGTCAATGGTCTTAATTCTCTTTGCCTTATTTTTCCC
ACTGCCTTACTACATTGAAATGCCAGGGGGGGCTTATGATATTAGATCTGTCTTGAAGGTCAATGGCAAAAAAGATAATG
AAAAAGGCTCCTATAACTTCGTAGCTGTAACAGTCAGTCATGCCACATTTGCTCAAATGCTTTATGCTTGGATGACACCA
TTCACTGAGATTTCATCAGCTGAAGATACAACTGGAGGATATAGTGATGCTGACTACTTACGCATTAATCAGTTTTACAT
GGAAACCTCTCAAAATGGTGCTATTTATCAGGCCTTAAAACTGGCTGATAAAGATGTTTCCTTGGATTATTTAGGGGTTT
ATGTCTTAGATGTAAGCAAAGATTCCACATTCAAAGGAAAACTAAACATCGCTGATACTGTGACCGCAGTCAATCATAAA
TCCTTTAAGAGTTCTAAAGAATTAATTGATTATGTGTCAGGTTTAAAACTGGGTGATAAGGTCAGTGTCCAATTCACTTC
AGATGGTAAAGATAAATCTAAAAATGGTAAAATCATCAAACTCAAAAATGGCAAAAATGGTATTGGTATTGGCTTAACAG
ATCATACCAAGGTCCATACCGATCAAGACATTGTTTTTTCAACAGATGGTGTCGGCGGTCCTAGTGCAGGCTTGATGTTC
ACACTTGATATCCTGGACCAAATTAATAAAGAAGACCTGCGAAAAGGTCGTAAAATTGCAGGGACAGGTACAATTGATCA
AGATGGCAGGGTTGGTGATATTGGTGGGGCAGGTTTAAAAGTTGTTGCTGCTGCTAACGAGGGGGCGGAAATCTTTTTTG
TGCCTAATAACCCAGTGGATAAAAAACTCAAAAAACGTTATCCTGATTTAAAAACCAATTATGACGAGGCCAAAGAAGCA
GCCAAACAAATTAAAACGAAAATGAAAATTGTTCCCGTAACAACAGCTAAAGAGGCCATAGATTATTTGAAAAAGACTAA
CTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (131-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-298)

3D structure

• AlphaFold DB: B9DUX6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	70.725	99.424	0.703