Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EHS18_RS10040 Genome accession   NZ_CP034098
Coordinates   2001837..2002553 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 80wphwpl_v1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1996837..2007553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHS18_RS10010 (EHS18_10010) - 1997048..1997674 (+) 627 WP_000522388.1 nitroreductase family protein -
  EHS18_RS10015 (EHS18_10015) - 1998035..1998820 (+) 786 WP_000867948.1 carbon-nitrogen family hydrolase -
  EHS18_RS14045 (EHS18_10020) - 1999423..1999557 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  EHS18_RS10025 (EHS18_10025) - 1999793..2000356 (+) 564 WP_001105709.1 accessory gene regulator AgrB -
  EHS18_RS10030 (EHS18_10030) agrD 2000360..2000500 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  EHS18_RS13850 agrC 2000525..2001818 (+) 1294 Protein_1884 quorum-sensing sensor histidine kinase AgrC -
  EHS18_RS10040 (EHS18_10040) agrA 2001837..2002553 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  EHS18_RS10045 (EHS18_10045) - 2002927..2003886 (-) 960 WP_124733828.1 carbohydrate kinase -
  EHS18_RS10050 (EHS18_10050) - 2003883..2005367 (-) 1485 WP_001791588.1 sucrose-6-phosphate hydrolase -
  EHS18_RS10055 (EHS18_10055) - 2005516..2006466 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=328946 EHS18_RS10040 WP_000688492.1 2001837..2002553(+) (agrA) [Staphylococcus aureus strain 80wphwpl_v1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=328946 EHS18_RS10040 WP_000688492.1 2001837..2002553(+) (agrA) [Staphylococcus aureus strain 80wphwpl_v1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment