Detailed information NTG0328945

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EHS18_RS09650
• Genome accession: NZ_CP034098
• Coordinates: 1926515..1927558 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 80wphwpl_v1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1921515..1932558

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EHS18_RS09620 (EHS18_09620)	-	1921936..1923192 (-)	1257	WP_001793983.1	aminopeptidase	-
EHS18_RS09625 (EHS18_09625)	-	1923195..1923395 (-)	201	WP_000180460.1	DUF1128 family protein	-
EHS18_RS09630 (EHS18_09630)	-	1923542..1924006 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
EHS18_RS09635 (EHS18_09635)	-	1924013..1924288 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
EHS18_RS09640 (EHS18_09640)	-	1924566..1925783 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
EHS18_RS09645 (EHS18_09645)	vraR	1925896..1926525 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
EHS18_RS09650 (EHS18_09650)	vraS	1926515..1927558 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
EHS18_RS09655 (EHS18_09655)	liaF	1927555..1928256 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
EHS18_RS09660 (EHS18_09660)	-	1928271..1928657 (-)	387	WP_001110178.1	hypothetical protein	-
EHS18_RS09665 (EHS18_09665)	map	1928874..1929632 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
EHS18_RS09670 (EHS18_09670)	-	1930217..1931203 (+)	987	WP_001014423.1	aromatic acid exporter family protein	-
EHS18_RS09675 (EHS18_09675)	-	1931392..1931805 (-)	414	WP_001643743.1	hypothetical protein	-
EHS18_RS09680 (EHS18_09680)	-	1931834..1931944 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=328945 EHS18_RS09650 WP_001017131.1 1926515..1927558(-) (vraS) [Staphylococcus aureus strain 80wphwpl_v1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=328945 EHS18_RS09650 WP_001017131.1 1926515..1927558(-) (vraS) [Staphylococcus aureus strain 80wphwpl_v1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1