Detailed information NTG0328568

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: EG219_RS15945
• Genome accession: NZ_CP034037
• Coordinates: 3210338..3211501 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain BCSo1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3205338..3216501

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EG219_RS15915 (EG219_15915)	-	3205602..3206021 (-)	420	WP_124693426.1	TIGR03826 family flagellar region protein	-
EG219_RS15920 (EG219_15920)	comFC	3206095..3206784 (-)	690	WP_197061611.1	phosphoribosyltransferase family protein	Machinery gene
EG219_RS15925 (EG219_15925)	-	3206790..3207074 (-)	285	WP_007407481.1	competence protein ComFB	-
EG219_RS15930 (EG219_15930)	comFA	3207132..3208517 (-)	1386	WP_007407482.1	DEAD/DEAH box helicase	Machinery gene
EG219_RS15935 (EG219_15935)	-	3208626..3209474 (-)	849	WP_007407483.1	DegV family protein	-
EG219_RS15940 (EG219_15940)	degU	3209572..3210261 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
EG219_RS15945 (EG219_15945)	degS	3210338..3211501 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
EG219_RS15950 (EG219_15950)	-	3211724..3212371 (+)	648	WP_007407485.1	YigZ family protein	-
EG219_RS15955 (EG219_15955)	-	3212376..3213596 (+)	1221	WP_007407486.1	LCP family protein	-
EG219_RS15960 (EG219_15960)	-	3213695..3214771 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
EG219_RS15965 (EG219_15965)	-	3214904..3216100 (-)	1197	WP_007407487.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=328568 EG219_RS15945 WP_007407484.1 3210338..3211501(-) (degS) [Bacillus velezensis strain BCSo1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=328568 EG219_RS15945 WP_007407484.1 3210338..3211501(-) (degS) [Bacillus velezensis strain BCSo1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCTTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
ATCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951