Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   EGH17_RS00335 Genome accession   NZ_CP034030
Coordinates   52594..55752 (-) Length   1052 a.a.
NCBI ID   WP_071236973.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain FQ02     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 47594..60752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGH17_RS00290 (EGH17_00290) - 47735..48298 (-) 564 WP_002214615.1 phosphoribosyltransferase family protein -
  EGH17_RS00300 (EGH17_00300) - 49479..49868 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  EGH17_RS14050 - 50031..50198 (-) 168 WP_003687280.1 glyoxalase -
  EGH17_RS00305 (EGH17_00305) - 50126..50410 (-) 285 WP_003687282.1 VOC family protein -
  EGH17_RS00310 (EGH17_00310) carA 50464..51597 (-) 1134 WP_003687283.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  EGH17_RS00335 (EGH17_00335) pilC 52594..55752 (-) 3159 WP_071236973.1 PilC family type IV pilus tip adhesin Machinery gene
  EGH17_RS13385 - 56084..56227 (+) 144 WP_154235612.1 hypothetical protein -
  EGH17_RS00360 (EGH17_00360) apbC 57193..58272 (-) 1080 WP_003698014.1 iron-sulfur cluster carrier protein ApbC -
  EGH17_RS00370 (EGH17_00370) - 58639..59148 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  EGH17_RS00380 (EGH17_00380) nadR 59489..59929 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  EGH17_RS00385 (EGH17_00385) hpaC 60044..60544 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1052 a.a.        Molecular weight: 115643.94 Da        Isoelectric Point: 9.8222

>NTDB_id=328367 EGH17_RS00335 WP_071236973.1 52594..55752(-) (pilC) [Neisseria gonorrhoeae strain FQ02]
MNKTLKRRVFRHTALYTAILMFSHTGGGGAMAQTHQYAIIMNERKQPEVKWKDQYNQSALKDKSRERTFSHTSQKNGLGI
TSNFISFNNNDELVSQQSGTAVFGTATYLPPYGKVSGFDTAELNKRGNAVNWIHTTRPGLAGYGYTGIRCGSTKDCPKLT
YKTRFSFDNPDLLKTRGGLDRHTEPSRENSPIYKLKDYPWLGVSFNLGGEGTAKDGRSSSKLVSSFDENNSNSNQNLVYT
TEDHRISLSNWQQETTAMAYYLNAKLHLLDKKGIKDITGKTVRLGVLKPSIDVKTQNTGLSGILNFWSKWDIKDNGQIPV
KLGLPEVKAGRCINEPNPNKNTQAPSPALTAPALWFGPGQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPARPGRHS
LAALNARDIKSREPNFNSRQTVIRLPGGVYRIGPTRNGIVGLNGNDGKNDTFGIYKDRLVTPEVDEWAKVLLPWTVRYYG
NDDIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPIVAVGGYLATSANDGMVHLFKRNGTNQRGYEL
KLSYIPGTMERKDIENQDSTLAKELRAFAEKGYVGDRYGVDGGFVLRRITDDQDREKHFFMFGAMGLGGRGAYALDLTKI
DSNNLTGVSMFDVQNDKNNNNNDSNRVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKDIVSSDNTTALYVYDLKDTLGTP
IAKIEAPGGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSSDKPSEWAVRTIFEGTKPITSAPAVSRLADKRVVI
FGTGSDLSEEDVVGKDQQYIYGIFDDDKGTGTVKVTVQNGTGGGLLEQTLTKENNTLFLSNNKASGGSADKGWVVKLREG
ERVTVKPTVVLRTAFVTIRSYTGMDKCGAQTAILGINTADGGALTPRSARPIVPDHNSVAQYSGHKKTTDGKSVPIGCMW
KNSKTVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMC
GIKRLSWREVFF

Nucleotide


Download         Length: 3159 bp        

>NTDB_id=328367 EGH17_RS00335 WP_071236973.1 52594..55752(-) (pilC) [Neisseria gonorrhoeae strain FQ02]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATACCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAACCCATCAATACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGAAGGATC
AATATAATCAATCAGCATTAAAGGACAAAAGCAGGGAGCGGACATTTAGCCATACGAGCCAGAAAAACGGCCTCGGCATC
ACAAGCAATTTTATCTCATTCAACAATAACGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCAC
CTACCTGCCGCCCTACGGCAAGGTTTCCGGCTTTGATACCGCCGAGCTGAACAAGCGCGGCAATGCCGTCAATTGGATTC
ATACCACCCGGCCCGGGCTGGCAGGCTACGGCTACACCGGTATCCGTTGCGGAAGTACCAAAGACTGTCCCAAACTTACC
TATAAAACCCGATTTTCCTTCGATAATCCCGACTTGCTAAAAACAAGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCG
CGAAAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGTGTGTCTTTCAATTTGGGCGGCGAGGGTACCGCCA
AAGATGGCAGATCATCCAGCAAATTGGTATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTCTATACG
ACAGAAGACCACCGTATTTCCCTTAGCAACTGGCAGCAAGAAACGACCGCCATGGCCTATTATCTGAACGCCAAGCTGCA
CCTGCTGGACAAAAAAGGGATTAAAGATATCACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGA
AGACACAAAATACGGGGCTTAGCGGCATTCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTC
AAGCTCGGCCTGCCGGAAGTCAAAGCAGGCCGCTGCATCAACGAACCGAACCCCAATAAGAATACCCAAGCCCCTTCGCC
GGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGGGCAAAATGGTAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCT
ACCCCGGCAGTTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGCCCGGCCCGGCCGGCATTCC
CTCGCCGCTTTGAATGCGCGGGATATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTGATCCGATTGCCGGG
CGGCGTGTACCGGATCGGCCCGACTCGCAACGGGATCGTGGGTTTGAATGGCAATGACGGCAAAAACGACACTTTCGGCA
TCTACAAGGACAGGCTCGTCACACCTGAGGTCGACGAGTGGGCAAAAGTGCTGCTGCCTTGGACGGTCCGGTATTACGGT
AATGACGATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAGCCAAAAATACCG
CATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATTGTCGCGGTCGGCG
GGTATCTGGCAACTTCTGCCAACGACGGGATGGTGCACCTGTTTAAAAGAAACGGCACAAACCAACGAGGCTACGAACTG
AAGCTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAAACCAAGACTCCACCCTCGCCAAAGAGCTGCGCGC
CTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAGG
ACAGGGAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTTGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAAATC
GACAGCAACAACCTGACCGGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAACAATGACAGTAATCGCGT
GAAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTT
ATGCGGCTAAAGATATTGTCAGCAGCGATAATACAACCGCGCTGTATGTGTATGATTTGAAAGACACCTTAGGTACGCCG
ATTGCAAAAATCGAAGCACCCGGCGGCAAAGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGT
CGATATCGCCTATGCCGGCGATCGGGGCGGGAATATGTACCGCTTTGATTTGAGCAGCGACAAGCCGTCCGAGTGGGCTG
TACGCACTATTTTCGAAGGCACAAAACCGATTACTTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTGGTCATC
TTCGGTACGGGCAGCGATTTGAGTGAAGAGGATGTAGTCGGTAAGGATCAACAATATATTTACGGTATCTTTGACGACGA
TAAGGGGACGGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGCTGCTCGAGCAAACGCTTACGAAGGAAA
ATAACACCTTGTTCCTGAGCAATAATAAGGCATCCGGCGGATCGGCCGATAAAGGCTGGGTAGTGAAATTGAGGGAAGGA
GAACGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTCACCATCCGCAGCTATACGGGCATGGACAAATG
TGGCGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGC
CGGATCACAATTCGGTTGCGCAATATTCCGGCCATAAGAAAACCACCGACGGCAAGTCCGTCCCCATAGGCTGTATGTGG
AAAAACAGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGACGAAAAGAAAAC
AGACGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATA
ACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGC
GGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(521-863)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

69.651

100

0.702

Multiple sequence alignment