Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   EGH20_RS00320 Genome accession   NZ_CP034026
Coordinates   52426..55560 (-) Length   1044 a.a.
NCBI ID   WP_124723882.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain FQ20     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 47426..60560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGH20_RS00290 (EGH20_00290) - 49112..49501 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  EGH20_RS13990 - 49664..49831 (-) 168 WP_003696645.1 glyoxalase -
  EGH20_RS00295 (EGH20_00295) - 49759..50043 (-) 285 WP_003687282.1 VOC family protein -
  EGH20_RS00300 (EGH20_00300) carA 50097..51230 (-) 1134 WP_047920606.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  EGH20_RS00320 (EGH20_00320) pilC 52426..55560 (-) 3135 WP_124723882.1 PilC family type IV pilus tip adhesin Machinery gene
  EGH20_RS00345 (EGH20_00345) apbC 57295..58374 (-) 1080 WP_003696650.1 iron-sulfur cluster carrier protein ApbC -
  EGH20_RS00355 (EGH20_00355) - 58741..59250 (+) 510 WP_003696651.1 protein disulfide oxidoreductase -
  EGH20_RS00365 (EGH20_00365) nadR 59591..60031 (+) 441 WP_003694725.1 MarR family adhesin repressor NadR -

Sequence

Protein


Download         Length: 1044 a.a.        Molecular weight: 114186.36 Da        Isoelectric Point: 9.8931

>NTDB_id=328266 EGH20_RS00320 WP_124723882.1 52426..55560(-) (pilC) [Neisseria gonorrhoeae strain FQ20]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGQAQAREYAIIMNERKQPEVKWKGQYNQSTLKGKGRERKFIYNRGRRGGGS
VSFNNSDELVSQQSGTAVFGTATYLPPYGKVSGFDTAELNKRGNAVNWIHTTRPGLAGYVYTGVHCGSYQCPKLTYKTRF
SFENTGLAKNANRLDKHPDPSRENSPIYKLKDYPWLGVSFNLGAEGTAKDGKVTNKLVSSFDENNSNNNLVYTTEGHPIS
LGDWQRESTAMAYYLNAKLHLLDKKRIEDITGKTVQLGTLKPGIDVKSANTGLGGILSFHAQWDIKDTGQIPVKLGLPEV
KARRCINKPNPNPKSKVPSPALTAPALWFAVQNGKVQMYSASVSTYPGSSSSRIFLQELKTRTDPARPGRHSLAALNERD
IKSREPNFNSRQTVIRLPGGVYRIAPGNSGRVAGFNGNDGKNDTFGIYKDRLVTPETNEWSEVLLPWTARYYGNDDIFKT
FNQPNNKKQSDKKQYSQRYRIRTKEDDNDKPRDLGDIVNSPITAVGGYLATAANDGMVHIFKKNGGSDERSYNLKLSYIP
GTMPRKDIESNGSTLAQELRAFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGFGGRGAYALDLSKIDSSNLT
GVSMFDVQNDKNNNKNDSNRVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKDIVSGDNTTALYVYDLGNGSGSLIKKIEV
KDGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSDSDPNKWSAKAIFEGTKPITSAPAVSRLADKRVVIFGTGSD
LSEDDVLNTDEQYIYGIFDDDEGTVKVTVQNGTGGGLLEQTLTKENNTLFLSNNKASGGSADKGWVVKLKEGERVTVKPI
VVLRTAFVTIRSYTGADKCGAETAILGINTADGGALTPRSARPIVPDHNSVAQYSGHKKTSKGKSIPIGCMEKGGKTVCP
NGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGIKRLSWR
EVFF

Nucleotide


Download         Length: 3135 bp        

>NTDB_id=328266 EGH20_RS00320 WP_124723882.1 52426..55560(-) (pilC) [Neisseria gonorrhoeae strain FQ20]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGCAGGCGCAAGCCCGTGAATACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGAAGGGTC
AATATAATCAATCAACATTAAAGGGCAAAGGCAGGGAACGCAAATTTATCTATAATAGAGGCAGACGGGGTGGAGGCTCT
GTCTCATTCAACAATAGCGATGAGCTTGTTTCCCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCC
CTACGGCAAGGTTTCCGGCTTTGATACCGCCGAGCTGAACAAGCGCGGCAATGCCGTCAATTGGATTCATACCACCCGGC
CCGGGCTGGCAGGCTACGTCTACACCGGTGTCCATTGCGGAAGCTACCAATGCCCCAAACTTACCTATAAAACCCGATTT
TCCTTCGAAAATACCGGTTTGGCAAAAAATGCAAACAGGCTGGATAAACACCCGGACCCAAGCCGCGAAAATTCGCCCAT
TTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCGCCAAAGATGGTAAGGTAA
CCAACAAATTGGTATCTTCTTTTGATGAAAACAATAGTAATAACAACCTCGTCTATACCACGGAAGGCCACCCTATTTCC
CTTGGCGACTGGCAGCGCGAAAGTACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAAGGAT
TGAAGATATCACCGGCAAAACAGTGCAGTTGGGCACCTTGAAACCGGGCATCGATGTGAAGTCGGCAAATACGGGGCTGG
GGGGCATACTATCTTTTCATGCTCAGTGGGACATTAAAGATACCGGGCAGATCCCGGTCAAGCTCGGTCTGCCGGAAGTC
AAGGCCAGGCGCTGCATCAATAAACCGAACCCCAATCCCAAATCCAAAGTCCCTTCGCCGGCACTGACCGCCCCCGCGCT
GTGGTTCGCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGGCAGCTCGAGCAGCCGCA
TCTTCCTCCAAGAGCTGAAAACTCGAACCGACCCCGCCCGGCCCGGCCGGCATTCCCTCGCCGCTTTGAATGAACGAGAT
ATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTCATCCGATTGCCGGGCGGCGTGTACCGGATCGCCCCGGG
CAATAGCGGCCGGGTCGCGGGTTTTAATGGCAATGACGGCAAAAACGACACTTTCGGCATCTACAAGGACAGGCTCGTCA
CACCTGAGACCAACGAGTGGAGCGAAGTGCTGCTGCCTTGGACGGCTCGGTATTACGGTAATGACGATATATTTAAAACA
TTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAGCCAAAGATACCGCATCCGCACAAAAGAAGATGA
CAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATAACGGCGGTCGGCGGGTATTTGGCAACCGCCGCGA
ACGACGGGATGGTGCATATCTTCAAAAAAAACGGCGGCAGTGATGAACGCAGCTACAATCTGAAGCTCAGCTACATCCCC
GGCACGATGCCGCGCAAGGATATTGAAAGCAACGGTTCTACACTCGCCCAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTA
TGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACAAGCAAAAACATTTCT
TTATGTTTGGTGCGATGGGTTTTGGCGGCAGAGGCGCGTATGCCTTGGATTTAAGCAAAATCGACAGCAGCAACCTGACC
GGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAAGAATGACAGTAATCGCGTGAAATTAGGCTACACCGT
CGGTACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGGCTAAAGATATTG
TCAGCGGCGATAATACAACCGCGCTGTATGTGTATGATTTGGGAAACGGCAGTGGTAGTCTGATTAAAAAAATCGAAGTG
AAGGACGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGG
CGACCGGGGCGGGAATATGTACCGCTTTGATTTGAGCGATTCCGATCCTAATAAATGGTCTGCAAAGGCTATTTTCGAAG
GCACAAAACCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTGGTTATCTTCGGCACGGGCAGCGAT
TTGAGTGAAGATGATGTACTGAATACGGACGAACAATATATTTACGGTATCTTTGACGACGATGAGGGGACGGTTAAGGT
AACGGTACAAAACGGCACGGGAGGCGGGCTGCTCGAGCAAACGCTTACGAAGGAAAATAACACCTTGTTCCTGAGCAATA
ATAAGGCATCCGGCGGATCGGCCGATAAAGGCTGGGTAGTGAAATTGAAGGAAGGAGAACGCGTTACCGTCAAACCGATC
GTGGTATTGCGTACCGCCTTTGTCACCATCCGCAGCTATACGGGCGCGGACAAATGTGGCGCGGAAACCGCCATTTTGGG
CATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGATCACAATTCGGTTGCGCAAT
ATTCCGGCCATAAGAAAACCTCCAAAGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGGCGGTAAAACCGTCTGCCCG
AACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGACGATTTCCCCGTCACGGCAGA
CGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTG
TGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGC
GAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(514-855)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

71.863

100

0.724

Multiple sequence alignment