Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   EGH11_RS11515 Genome accession   NZ_CP034018
Coordinates   1953842..1956943 (-) Length   1033 a.a.
NCBI ID   WP_165865822.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain FQ82     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1948842..1961943
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGH11_RS11490 (EGH11_11490) - 1948861..1950087 (+) 1227 WP_003697786.1 PilT/PilU family type 4a pilus ATPase -
  EGH11_RS11495 (EGH11_11495) yccS 1950204..1952354 (+) 2151 WP_003690198.1 YccS family putative transporter -
  EGH11_RS11505 (EGH11_11505) - 1952906..1953190 (-) 285 WP_071198174.1 GIY-YIG nuclease family protein -
  EGH11_RS11515 (EGH11_11515) pilC 1953842..1956943 (-) 3102 WP_165865822.1 PilC family type IV pilus tip adhesin Machinery gene
  EGH11_RS11525 (EGH11_11525) - 1957635..1957898 (+) 264 WP_017147189.1 hypothetical protein -
  EGH11_RS11530 (EGH11_11530) gnd 1957978..1959426 (+) 1449 WP_003688061.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  EGH11_RS11535 (EGH11_11535) waaA 1959489..1960760 (+) 1272 WP_025455875.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  EGH11_RS11540 (EGH11_11540) - 1960801..1961250 (+) 450 WP_003688065.1 CopD family copper resistance protein -

Sequence

Protein


Download         Length: 1033 a.a.        Molecular weight: 112209.14 Da        Isoelectric Point: 9.6950

>NTDB_id=328115 EGH11_RS11515 WP_165865822.1 1953842..1956943(-) (pilC) [Neisseria gonorrhoeae strain FQ82]
MNKTLKRQVFRHTALYAAILMFSHTGGGGGQAQARDYAIVMNGQNQPEVKSNVPSSIRDKDRKREYTHHGYNTGGGSVSF
DNSDELVSQQSGTAVFGTATYLPPYGKVSGFDTDSLKGRANAAGWIRTTRIALAGYSYADVVCRDITGCPKLVYETKFAF
GQQGLQRKGSKLDIYEDKSRDNSPIYKLKDHPWLGVSFNLGSENTVKNSKSLNKLISSFSEGNNNQNIVSTTRDHPISLG
DSQREHTAVAYYLNAKLHLLDKKKIKDITGKTVQLGVLKPSIDVKTQNTGLAGLLNFWSKWDIKDNGQIPVKLGLPEVKA
GRCTNKPNPNNNTKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSKIFLQNLSRNDDKNKPGRYSLKSLNDGEI
QSRQPSFNGRQTIIRLDDGVHLIKLNGSKDEVAAFVNLNGNNTGKNDTFGIVKEANVNLDADEWKKVLLPWTVRGPGNDD
KFKSINRESDKYSQRYRIRENGNRDLGDIVNSPIVAVGGYLATAANDGMVHIFKKNGGSDERSYNLKLSYIPGTMPRQYF
DNDTSALKGSTLAQELRTFAEKGYVGDRYGVDGGFVLRQVEDRVFMFGAMGFGGRGAYALDLSKINGNYPAAAPLFDVKD
GDNNGKNRVKVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKDIVSSDNTTALYVYDLKDTLGTPIAKIEVQGGKGGLSSP
TLVDKDLDGIVDIAYAGDRGGNMYRFDLSNSDPNKWSAKAIFEGTKPITSAPAVSRLADKRVVIFGTGSDLSEQDVVGTD
QQYIYGIFDDDKPTVNVKVTNGTGGGLLEQVLSEENKILFLINNKASGGSADKGWVVKLREGERVTVKPTVVLRTAFVTI
RKYNDGGCGAETAILGINTADGGALTPRSARPIVPDHDSVAQYSGHKKTAGGKSVPIGCMWKNSKTVCPNGYVYDKPVNV
RYLDETETDGFSTTADGDAGGSGIDPAGRRPGKNNRCFSKKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3102 bp        

>NTDB_id=328115 EGH11_RS11515 WP_165865822.1 1953842..1956943(-) (pilC) [Neisseria gonorrhoeae strain FQ82]
ATGAATAAAACTTTGAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGCAGGCGCAAGCCCGTGACTACGCTATTGTCATGAACGGGCAAAACCAGCCCGAGGTAAAGTCGAATGTGC
CATCTTCAATAAGGGACAAAGACAGGAAGCGCGAATATACTCATCATGGGTACAACACAGGAGGAGGCTCTGTCTCATTC
GACAATAGCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGGCAA
GGTTTCCGGTTTTGATACCGATAGTCTGAAAGGGCGCGCCAATGCCGCCGGTTGGATTCGTACCACCCGCATCGCGCTGG
CAGGCTACAGCTACGCCGATGTCGTATGCAGAGACATCACAGGCTGTCCCAAACTTGTCTATGAGACCAAATTTGCCTTC
GGTCAACAAGGGTTGCAAAGAAAGGGCAGCAAGCTGGATATATACGAAGACAAAAGCCGCGACAATTCGCCCATTTACAA
ATTGAAGGATCATCCCTGGTTGGGCGTGTCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATAGCAAATCACTCAACA
AATTGATATCTTCTTTTAGTGAAGGCAATAATAATCAAAACATCGTCTCTACGACACGAGACCACCCTATTTCCCTTGGC
GACTCGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAGCTGCACCTGCTGGACAAAAAAAAGATTAAAGA
TATCACCGGCAAAACAGTGCAGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGACACAAAATACGGGGCTTGCCGGCT
TGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCGGAAGTCAAAGCC
GGGCGCTGCACCAACAAACCGAACCCCAATAATAATACCAAAGCCCCTTCGCCGGCACTGACCGCCCCCGCGCTGTGGTT
CGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCTACCCCGACAGTTCGAGCAGCAAAATTT
TCCTGCAAAACCTTTCCCGCAATGATGACAAAAACAAACCGGGCCGCTATTCCCTCAAATCTTTGAATGATGGTGAGATT
CAAAGTCGACAGCCGAGTTTCAACGGGCGGCAAACAATCATCCGATTGGATGACGGCGTACATTTGATCAAACTGAATGG
AAGCAAGGATGAGGTCGCCGCTTTTGTCAATTTAAATGGAAACAACACCGGCAAAAACGACACTTTCGGCATTGTTAAGG
AAGCGAACGTCAATCTTGACGCCGACGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTCCCGGTAATGACGAT
AAATTTAAATCAATTAACCGAGAATCAGACAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAATCGCGATTTGGG
CGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGGGTATTTGGCAACCGCCGCGAACGACGGGATGGTGCATATCTTCA
AAAAAAACGGCGGCAGTGATGAACGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTT
GATAACGACACTTCCGCTCTCAAAGGCTCCACCCTCGCCCAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGA
CCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGTCAAGTTGAAGACCGCGTGTTTATGTTCGGCGCGATGGGTTTTGGCG
GCAGAGGCGCGTATGCCTTGGATTTAAGCAAAATCAACGGAAATTATCCGGCCGCCGCTCCCCTGTTTGATGTCAAAGAT
GGCGATAATAACGGCAAAAATCGCGTGAAAGTGAAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCAAAA
CGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGGCTAAAGATATTGTCAGCAGCGATAATACAACCGCGCTGTATG
TGTATGATTTGAAAGACACCTTAGGTACGCCGATTGCAAAAATCGAAGTGCAGGGCGGCAAAGGCGGGCTTTCGTCCCCC
ACGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGA
TTTGAGCAATTCCGATCCTAATAAATGGTCTGCAAAGGCTATTTTCGAAGGCACAAAACCGATTACTTCCGCGCCCGCCG
TTTCCCGACTGGCAGACAAACGCGTCGTCATCTTCGGCACGGGCAGCGATTTGAGTGAACAGGATGTAGTCGGTACGGAT
CAACAATATATTTACGGTATCTTTGACGACGATAAGCCGACGGTTAATGTAAAGGTAACAAACGGCACGGGAGGCGGGCT
GCTCGAGCAAGTGCTTAGCGAGGAAAATAAAATCTTGTTCCTGATAAATAATAAGGCATCCGGCGGATCGGCCGATAAAG
GCTGGGTAGTGAAATTGAGGGAAGGAGAACGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTAACCATC
CGCAAATATAACGACGGCGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCC
GAGAAGCGCGCGCCCGATTGTGCCGGATCACGATTCGGTTGCGCAATATTCCGGCCATAAGAAAACCGCCGGCGGCAAGT
CCGTCCCCATAGGCTGCATGTGGAAAAACAGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTG
CGTTATCTGGATGAAACGGAAACAGACGGATTTTCAACGACGGCGGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGC
CGGCAGGCGTCCCGGCAAAAACAACCGCTGCTTCTCCAAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCT
TGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(506-844)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

70.56

100

0.719

Multiple sequence alignment