Detailed information NTG0328059

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: EGH15_RS09980
• Genome accession: NZ_CP034016
• Coordinates: 1692759..1693619 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain FQ84
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1687759..1698619

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGH15_RS09960 (EGH15_09960)	dapD	1688269..1689090 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
EGH15_RS09965 (EGH15_09965)	pgi	1689300..1690943 (-)	1644	WP_003697594.1	glucose-6-phosphate isomerase	-
EGH15_RS09975 (EGH15_09975)	pilG	1691453..1692685 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
EGH15_RS09980 (EGH15_09980)	pilD	1692759..1693619 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
EGH15_RS09985 (EGH15_09985)	coaE	1693616..1694248 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
EGH15_RS09990 (EGH15_09990)	-	1694241..1694450 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
EGH15_RS09995 (EGH15_09995)	pilF	1694536..1696212 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
EGH15_RS10010 (EGH15_10010)	-	1696550..1696996 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
EGH15_RS10015 (EGH15_10015)	-	1697000..1697974 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
EGH15_RS10025 (EGH15_10025)	rplU	1698198..1698506 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=328059 EGH15_RS09980 WP_003689814.1 1692759..1693619(+) (pilD) [Neisseria gonorrhoeae strain FQ84]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=328059 EGH15_RS09980 WP_003689814.1 1692759..1693619(+) (pilD) [Neisseria gonorrhoeae strain FQ84]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441