Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   EGH15_RS00330 Genome accession   NZ_CP034016
Coordinates   53009..56170 (-) Length   1053 a.a.
NCBI ID   WP_124693279.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain FQ84     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 48009..61170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGH15_RS00295 (EGH15_00295) - 49240..49629 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  EGH15_RS13990 - 49792..49959 (-) 168 WP_003687280.1 glyoxalase -
  EGH15_RS00300 (EGH15_00300) - 49887..50171 (-) 285 WP_003687282.1 VOC family protein -
  EGH15_RS00305 (EGH15_00305) carA 50225..51358 (-) 1134 WP_003687283.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  EGH15_RS00320 (EGH15_00320) - 52073..52357 (-) 285 WP_003701816.1 GIY-YIG nuclease family protein -
  EGH15_RS00330 (EGH15_00330) pilC 53009..56170 (-) 3162 WP_124693279.1 PilC family type IV pilus tip adhesin Machinery gene
  EGH15_RS00345 (EGH15_00345) apbC 57578..58657 (-) 1080 WP_071198195.1 iron-sulfur cluster carrier protein ApbC -
  EGH15_RS00355 (EGH15_00355) - 59031..59540 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  EGH15_RS00365 (EGH15_00365) nadR 59881..60321 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  EGH15_RS00370 (EGH15_00370) hpaC 60437..60937 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1053 a.a.        Molecular weight: 115513.81 Da        Isoelectric Point: 9.8407

>NTDB_id=328025 EGH15_RS00330 WP_124693279.1 53009..56170(-) (pilC) [Neisseria gonorrhoeae strain FQ84]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAMAQTSNYAIIMNERKQPEVKWEGQYNQSALKDKSRERTFSHTSQKNSLGR
TSNFISFNNNDTLVSQQSGTAVFGTATYLPPYGKVSGFDTDSLKGRANAAGWIRTTRPGLAGYAYTGIRCGHARDCPKLT
YKTRFSFDNPNLAKTGGRLDRHTESSRENSPIYKLKDYPWLGVSFNLGAEGTAKDGRSSSRLISSFDENNSNSNQNLVYT
TEGRDISLGNWQSESTAVAYYLNAKLHLLDKKKIKDITGKTVQLGVLKPSIDVKTQNTGLAGLLNFWSKWDIKDNGQIPV
KLGLPEVKAGRCTNKPNPNNNTKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPARPGRHS
LAALNARDIKSREPNFNSRQTVIRLPGGVYRIAPTRDRIVGLNGNDGKNDTFGIYKERLVTPDDDEWAKVLLPWTVRYYG
NDDIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPIVAVDGYLATSANDGMVHLFKRNGTDQRGYEL
KLSYIPGTMPRQYFDNDTSALQDSDLAKELRTFAEKGYVGDRYGVDGGFVLRRITDDQDRQKHFFMFGAMGFGGRGAYAL
DLSKIDSSNLTGVSMFDVKDGDNNGKNRVEVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKDIVSSDNTTALYVYDLKDT
LGTPIAKIEVQGGKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSNSDPNKWSAKAIFEGTKPITSAPAVSRLADK
RVVIFGTGSDLSEQDVVGTDQQYIYGIFDDDKPTVNVKVTNGTGGGLLEQVLSEENKILFLINNKASGGSADKGWVVKLR
EGERVTVKPTVVLRTAFVTIRKYNDGGCGAETAILGINTADGGALTPRSARPIVPDHDSVAQYSGHKKTAGGKSVPIGCM
WKNGKTVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPM
CGIKRLSWREVFF

Nucleotide


Download         Length: 3162 bp        

>NTDB_id=328025 EGH15_RS00330 WP_124693279.1 53009..56170(-) (pilC) [Neisseria gonorrhoeae strain FQ84]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAACCAGTAACTACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGGAGGGTC
AATATAATCAATCAGCATTAAAGGACAAAAGCAGGGAGCGGACATTTAGCCATACGAGCCAGAAAAACAGCCTCGGCAGG
ACAAGCAATTTTATCTCATTCAACAATAACGATACCCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCAC
CTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGTCTGAAAGGGCGCGCCAATGCCGCCGGTTGGATTC
GTACCACCCGGCCCGGGCTGGCAGGCTACGCCTACACCGGTATCCGTTGCGGACATGCCCGAGACTGTCCCAAACTTACC
TATAAAACCCGATTTTCCTTCGATAATCCCAACTTGGCAAAAACAGGAGGCAGGCTGGATAGGCACACAGAGTCAAGCCG
CGAAAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCGCCA
AAGATGGCAGATCATCCAGCAGATTGATATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTCTATACC
ACGGAAGGCCGCGATATTTCCTTGGGCAACTGGCAGAGCGAAAGTACCGCCGTGGCCTATTATCTGAACGCCAAGCTGCA
CCTGCTGGACAAAAAAAAGATTAAAGATATCACCGGCAAAACAGTGCAGTTGGGTGTCTTGAAGCCGAGCATCGATGTGA
AGACACAAAATACGGGGCTTGCCGGCTTGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTC
AAGCTCGGCCTGCCGGAAGTCAAAGCCGGGCGCTGCACCAACAAACCGAACCCCAATAATAATACCAAAGCCCCTTCGCC
GGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCT
ACCCCGGCAGCTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGCCCGGCCCGGCCGGCATTCC
CTCGCCGCTTTGAATGCGCGGGATATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTGATCCGATTGCCGGG
CGGCGTGTACCGGATCGCCCCGACTCGCGACAGGATCGTGGGTTTGAATGGCAATGACGGCAAAAACGACACTTTCGGCA
TCTACAAGGAAAGGTTAGTCACACCTGATGACGACGAGTGGGCAAAAGTGCTGCTGCCTTGGACGGTCCGGTATTACGGT
AATGACGATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAGCCAAAAATACCG
CATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATTGTCGCGGTCGACG
GGTATTTGGCAACTTCTGCCAACGACGGGATGGTGCACCTGTTTAAAAGAAACGGCACAGACCAACGAGGCTACGAACTG
AAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACTTCCGCTCTCCAAGACTCCGACCTCGC
CAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCA
TTACAGATGACCAGGACAGGCAAAAACATTTCTTTATGTTTGGTGCGATGGGTTTTGGCGGCAGAGGCGCGTATGCCTTG
GATTTAAGCAAAATCGACAGCAGCAACCTGACCGGCGTTTCCATGTTTGATGTCAAAGATGGCGATAATAACGGCAAAAA
TCGCGTGGAAGTGAAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCC
TCGCCTCCGGTTATGCGGCTAAAGATATTGTCAGCAGCGATAATACAACCGCGCTGTATGTGTATGATTTGAAAGACACC
TTAGGTACGCCGATTGCAAAAATCGAAGTGCAGGGCGGCAAAGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTT
GGACGGCATTGTCGATATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGATTTGAGCAATTCCGATCCTA
ATAAATGGTCTGCAAAGGCTATTTTCGAAGGCACAAAACCGATTACTTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAA
CGCGTCGTCATCTTCGGCACGGGCAGCGATTTGAGTGAACAGGATGTAGTCGGTACGGATCAACAATATATTTACGGTAT
CTTTGACGACGATAAGCCGACGGTTAATGTAAAGGTAACAAACGGCACGGGAGGCGGGCTGCTCGAGCAAGTGCTTAGCG
AGGAAAATAAAATCTTGTTCCTGATAAATAATAAGGCATCCGGCGGATCGGCCGATAAAGGCTGGGTAGTGAAATTGAGG
GAAGGAGAACGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTAACCATCCGCAAATATAACGACGGCGG
CTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTG
TGCCGGATCACGATTCGGTTGCGCAATATTCCGGCCATAAGAAAACCGCCGGCGGCAAGTCCGTCCCCATAGGCTGCATG
TGGAAAAACGGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGTTATCTGGACGAAAAGAA
AACAGACGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCA
ATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATG
TGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(535-864)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

68.644

100

0.692

Multiple sequence alignment