Detailed information NTG0327699

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EFD75_RS13570
• Genome accession: NZ_CP033990
• Coordinates: 2716557..2717444 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain P1D14C1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2711557..2722444

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EFD75_RS13540 (EFD75_14175)	-	2711576..2711668 (+)	93	WP_010956583.1	hypothetical protein	-
EFD75_RS13545 (EFD75_14180)	-	2711776..2712273 (-)	498	WP_001065268.1	glutathione peroxidase	-
EFD75_RS13550 (EFD75_14185)	-	2712283..2712543 (-)	261	WP_001791974.1	hypothetical protein	-
EFD75_RS13555 (EFD75_14195)	-	2712925..2713038 (-)	114	Protein_2618	hypothetical protein	-
EFD75_RS13560 (EFD75_14200)	-	2713697..2715697 (-)	2001	WP_000776751.1	ABC transporter permease	-
EFD75_RS13565 (EFD75_14205)	-	2715694..2716449 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EFD75_RS13570 (EFD75_14210)	braS	2716557..2717444 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EFD75_RS13575 (EFD75_14215)	braR	2717455..2718120 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EFD75_RS13580 (EFD75_14220)	-	2718146..2718346 (-)	201	WP_000604730.1	hypothetical protein	-
EFD75_RS13585 (EFD75_14225)	-	2718544..2719968 (+)	1425	WP_000953755.1	alkaline phosphatase	-
EFD75_RS14250 (EFD75_14230)	-	2720028..2720129 (-)	102	WP_000731976.1	SE2200 family small protein	-
EFD75_RS13595 (EFD75_14235)	-	2720251..2720706 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EFD75_RS13600 (EFD75_14240)	-	2720951..2721712 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=327699 EFD75_RS13570 WP_000143425.1 2716557..2717444(-) (braS) [Staphylococcus aureus strain P1D14C1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=327699 EFD75_RS13570 WP_000143425.1 2716557..2717444(-) (braS) [Staphylococcus aureus strain P1D14C1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1