Detailed information NTG0327656

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EFD76_RS13965
• Genome accession: NZ_CP033987
• Coordinates: 2763731..2764618 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain P2D1C1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2758731..2769618

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EFD76_RS13935 (EFD76_14610)	-	2758750..2758842 (+)	93	WP_010956583.1	hypothetical protein	-
EFD76_RS13940 (EFD76_14615)	-	2758950..2759447 (-)	498	WP_001065268.1	glutathione peroxidase	-
EFD76_RS13945 (EFD76_14620)	-	2759457..2759717 (-)	261	WP_001791974.1	hypothetical protein	-
EFD76_RS13950 (EFD76_14630)	-	2760099..2760212 (-)	114	Protein_2671	hypothetical protein	-
EFD76_RS13955 (EFD76_14635)	-	2760871..2762871 (-)	2001	WP_000776751.1	ABC transporter permease	-
EFD76_RS13960 (EFD76_14640)	-	2762868..2763623 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EFD76_RS13965 (EFD76_14645)	braS	2763731..2764618 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EFD76_RS13970 (EFD76_14650)	braR	2764629..2765294 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EFD76_RS13975 (EFD76_14655)	-	2765320..2765520 (-)	201	WP_000604730.1	hypothetical protein	-
EFD76_RS13980 (EFD76_14660)	-	2765718..2767142 (+)	1425	WP_000953755.1	alkaline phosphatase	-
EFD76_RS14710 (EFD76_14665)	-	2767202..2767303 (-)	102	WP_000731976.1	SE2200 family small protein	-
EFD76_RS13990 (EFD76_14670)	-	2767425..2767880 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EFD76_RS13995 (EFD76_14675)	-	2768125..2768886 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=327656 EFD76_RS13965 WP_000143425.1 2763731..2764618(-) (braS) [Staphylococcus aureus strain P2D1C1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=327656 EFD76_RS13965 WP_000143425.1 2763731..2764618(-) (braS) [Staphylococcus aureus strain P2D1C1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1