Detailed information NTG0327613

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EFD77_RS13985
• Genome accession: NZ_CP033982
• Coordinates: 2763726..2764613 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain P2D8C1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2758726..2769613

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EFD77_RS13955 (EFD77_14610)	-	2758745..2758837 (+)	93	WP_010956583.1	hypothetical protein	-
EFD77_RS13960 (EFD77_14615)	-	2758945..2759442 (-)	498	WP_001065268.1	glutathione peroxidase	-
EFD77_RS13965 (EFD77_14620)	-	2759452..2759712 (-)	261	WP_001791974.1	hypothetical protein	-
EFD77_RS13970 (EFD77_14630)	-	2760094..2760207 (-)	114	Protein_2671	hypothetical protein	-
EFD77_RS13975 (EFD77_14635)	-	2760866..2762866 (-)	2001	WP_000776751.1	ABC transporter permease	-
EFD77_RS13980 (EFD77_14640)	-	2762863..2763618 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EFD77_RS13985 (EFD77_14645)	braS	2763726..2764613 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EFD77_RS13990 (EFD77_14650)	braR	2764624..2765289 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EFD77_RS13995 (EFD77_14655)	-	2765315..2765515 (-)	201	WP_000604730.1	hypothetical protein	-
EFD77_RS14000 (EFD77_14660)	-	2765713..2767137 (+)	1425	WP_000953755.1	alkaline phosphatase	-
EFD77_RS14730 (EFD77_14665)	-	2767197..2767298 (-)	102	WP_000731976.1	SE2200 family small protein	-
EFD77_RS14010 (EFD77_14670)	-	2767420..2767875 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EFD77_RS14015 (EFD77_14675)	-	2768120..2768881 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=327613 EFD77_RS13985 WP_000143425.1 2763726..2764613(-) (braS) [Staphylococcus aureus strain P2D8C1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=327613 EFD77_RS13985 WP_000143425.1 2763726..2764613(-) (braS) [Staphylococcus aureus strain P2D8C1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1