Detailed information NTG0327608

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: FNV59_RS06060
• Genome accession: NZ_CP041650
• Coordinates: 1293181..1295823 (+)
• Length: 880 a.a.
• NCBI ID: WP_143599993.1
• Uniprot ID: A0ABU3V3B1
• Organism: Streptomyces sp. RLB1-8
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1288181..1300823

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FNV59_RS06040 (FNV59_06185)	dnaK	1289388..1291292 (+)	1905	WP_097282697.1	molecular chaperone DnaK	-
FNV59_RS06045 (FNV59_06190)	-	1291302..1291814 (+)	513	WP_143599992.1	nucleotide exchange factor GrpE	-
FNV59_RS06050 (FNV59_06195)	-	1291821..1292798 (+)	978	WP_097282699.1	DnaJ C-terminal domain-containing protein	-
FNV59_RS06055 (FNV59_06200)	-	1292795..1293190 (+)	396	WP_097282700.1	chaperone modulator CbpM	-
FNV59_RS06060 (FNV59_06205)	clpC	1293181..1295823 (+)	2643	WP_143599993.1	ATP-dependent chaperone ClpB	Regulator
FNV59_RS06065 (FNV59_06210)	trxA	1295820..1296278 (+)	459	WP_225900139.1	thioredoxin	-
FNV59_RS06070 (FNV59_06215)	-	1296372..1297172 (-)	801	WP_205522219.1	metallophosphoesterase family protein	-
FNV59_RS06075 (FNV59_06220)	-	1297241..1298029 (-)	789	WP_143599994.1	IclR family transcriptional regulator	-
FNV59_RS06080 (FNV59_06225)	-	1298136..1299095 (+)	960	WP_143599995.1	5-dehydro-4-deoxyglucarate dehydratase	-
FNV59_RS06085 (FNV59_06230)	-	1299225..1300562 (+)	1338	WP_143599996.1	gluconate:H+ symporter	-

Sequence

Protein

• Length: 880 a.a.
• Molecular weight: 97902.84 Da
• Isoelectric Point: 4.8955

>NTDB_id=327608 FNV59_RS06060 WP_143599993.1 1293181..1295823(+) (clpC) [Streptomyces sp. RLB1-8]
MDMNRLTQKSQEALQEAQTIAGRLNQTEVDGEHLLLALLDQPDGLIPRLIDQSGADTRALRTALNEELARRPKVTGPGAT
PGQVYVTQRLAKVLDSAEQEARRLKDEYVSVEHLVLALADEGSRTASGRLLKEHGVSKDGFLSALTRIRGNQRVTSATPE
AAYEALEKYGRDLVAEARSGRMDPVIGRDAEIRRVIQILSRKTKNNPVLIGDPGVGKTAIVEGLAQRIVRGDVPDGLRDR
TIFSLDMSSLVAGAKYRGEFEERLQAVLSEVKAGEGRILLFIDELHTVVGAGGGAEGAMDAGNMLKPMLARGELHMIGAT
TLDEYRKYVESDAALERRFQQVQVDEPSVEDTISILRGLRERLEVFHGVKIQDTALVAAATLSHRYISDRFLPDKAIDLV
DEACARLRTEIDSMPAELDEITRRVTRLEIEDAALAKETDAASQKRLDELRRELADLRAEADAMHAQWEAERQAIRRVQE
LRQELEHVRQEAEEAERSYDLNRAAELRYGRLTELERRLTAEEEALAAKQGENRLLREVVTEDEIAEIVAAWTGIPVTRL
QEGEREKLLRLDEILTERVIGQDEAVKLVTDAIIRARSGIRDPRRPIGSFIFLGPTGVGKTELAKALAAALFDSEESIVR
LDMSEYQERHTVSRLVGAPPGYVGYEEGGQLTEAVRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRVTDSQGRTVDFRN
TVIIMTSNIGSAHLLDGVTADGEIKSDARALVMSDLRGHFRPEFLNRVDDIVLFKPLGMTQIERIVELQFDDLRRRLAER
QITVELTDAARELIAEQGFDPVYGARPLRRYISHEVETMVGRALIRGDVQDGTTIRVDAQNGELVVTYGGQAAPDVRKAA

Nucleotide

• Length: 2643 bp

>NTDB_id=327608 FNV59_RS06060 WP_143599993.1 1293181..1295823(+) (clpC) [Streptomyces sp. RLB1-8]
GTGGATATGAACCGGCTCACCCAGAAGTCCCAGGAGGCGCTCCAGGAAGCGCAGACCATCGCCGGCCGGCTGAACCAGAC
CGAGGTCGACGGCGAGCATCTGCTCCTCGCCCTGCTCGACCAGCCCGACGGCCTGATACCGCGGCTGATCGACCAGTCGG
GCGCCGACACCCGGGCCCTGCGCACCGCGCTGAACGAGGAGTTGGCCCGCAGGCCGAAAGTGACCGGCCCCGGTGCCACC
CCAGGACAGGTGTACGTCACCCAACGGCTGGCGAAGGTACTGGACTCGGCCGAGCAGGAGGCCAGGCGGCTCAAGGACGA
GTACGTGTCCGTCGAGCACCTGGTGCTCGCACTCGCCGACGAGGGCTCCCGCACGGCATCCGGCCGACTGCTCAAGGAGC
ACGGCGTCAGCAAGGACGGGTTCCTGTCCGCGCTCACCCGGATCCGTGGCAACCAGCGCGTCACCTCGGCGACGCCCGAA
GCGGCGTACGAGGCACTGGAGAAGTACGGCCGTGATCTGGTCGCCGAGGCACGCAGCGGCAGGATGGACCCGGTGATCGG
CCGGGACGCGGAGATCCGCCGGGTCATCCAGATCCTGAGCCGCAAGACGAAGAACAACCCCGTCCTCATCGGTGACCCGG
GGGTCGGCAAGACCGCCATCGTGGAGGGACTCGCCCAGCGCATCGTGCGGGGCGACGTGCCCGACGGGCTGCGCGACCGG
ACGATCTTCTCGCTCGACATGAGTTCGCTGGTAGCGGGCGCCAAGTACCGCGGCGAGTTCGAGGAACGGCTGCAGGCCGT
ACTGAGCGAGGTCAAGGCGGGCGAGGGGCGCATCCTGCTCTTCATCGACGAACTGCACACGGTCGTCGGCGCGGGCGGCG
GTGCCGAGGGCGCGATGGACGCCGGGAACATGCTCAAGCCCATGCTGGCACGCGGCGAGCTGCACATGATCGGCGCCACC
ACCCTCGACGAGTACCGCAAGTACGTCGAGTCCGACGCGGCCCTCGAACGCCGCTTCCAGCAGGTGCAGGTGGACGAGCC
GAGCGTCGAGGACACCATCTCCATCCTGCGCGGACTGCGCGAGCGCCTGGAGGTCTTCCACGGTGTGAAGATCCAGGACA
CCGCGCTGGTCGCGGCGGCGACTCTCAGCCACCGCTACATCTCCGACCGGTTCCTGCCGGACAAGGCCATCGACCTGGTC
GACGAGGCGTGCGCGCGGCTGCGTACCGAGATCGACTCCATGCCCGCCGAACTGGACGAGATCACCCGCCGGGTGACCCG
TCTGGAGATCGAGGACGCGGCGCTCGCCAAGGAGACCGACGCCGCCAGCCAGAAGCGACTCGACGAGCTGCGCCGCGAAC
TGGCCGACCTGCGCGCCGAGGCCGACGCCATGCACGCCCAGTGGGAGGCCGAACGCCAGGCCATCCGCCGGGTGCAGGAG
CTGCGCCAGGAACTGGAGCACGTCCGGCAGGAGGCCGAGGAGGCCGAACGCAGCTACGACCTCAACCGGGCCGCCGAACT
GCGCTACGGCAGGCTCACCGAACTCGAACGCCGCCTCACGGCGGAGGAGGAGGCGCTGGCCGCCAAGCAGGGCGAGAACC
GGCTGCTGCGCGAGGTCGTCACCGAGGACGAGATCGCGGAGATCGTCGCCGCCTGGACCGGCATCCCCGTCACCCGCCTC
CAGGAGGGCGAGCGCGAGAAGCTGCTGCGCCTCGACGAGATCCTCACCGAGCGGGTGATCGGCCAGGACGAGGCGGTCAA
GCTGGTCACCGACGCGATCATCAGGGCCCGCTCCGGGATCCGGGACCCGCGCCGGCCGATCGGCTCATTCATCTTCCTCG
GCCCCACCGGCGTCGGGAAGACCGAACTGGCCAAGGCGCTCGCCGCGGCGCTGTTCGACTCGGAGGAGAGCATCGTCCGC
CTGGACATGAGCGAGTACCAGGAACGGCACACCGTCAGCAGGCTGGTGGGAGCGCCTCCCGGATACGTCGGCTACGAGGA
GGGCGGCCAGCTCACCGAGGCGGTGCGCCGCAAGCCGTACTCCGTGGTCCTGTTCGACGAGATCGAGAAGGCCCACCCCG
ACGTCTTCAACATCCTGCTGCAGGTCCTCGACGACGGCCGCGTCACCGACTCCCAGGGCCGCACCGTCGACTTCCGCAAC
ACCGTGATCATCATGACCTCCAACATCGGCTCGGCCCACCTGCTGGACGGGGTGACCGCCGACGGCGAGATCAAGTCCGA
CGCGCGAGCACTGGTGATGAGCGATCTGCGGGGCCACTTCCGGCCCGAGTTCCTCAACCGCGTCGACGACATCGTGCTGT
TCAAGCCGCTGGGCATGACGCAGATCGAGCGGATCGTGGAGCTGCAGTTCGACGACCTGCGCCGACGGCTGGCCGAACGG
CAGATCACGGTCGAGCTCACCGACGCCGCCCGCGAACTCATCGCCGAGCAGGGCTTCGACCCCGTGTACGGAGCCCGGCC
GCTGCGCCGGTACATCTCGCACGAGGTCGAGACGATGGTCGGCCGGGCGTTGATCCGCGGTGACGTGCAGGACGGCACGA
CGATCCGCGTCGACGCCCAGAACGGCGAACTCGTCGTCACCTACGGCGGACAGGCCGCACCGGACGTGCGGAAAGCCGCG
TGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (777-857)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-150)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• AAA lid domain (AAA_lid_9) (348-450)

• ATPase family associated with various cellular activities (AAA) (AAA) (208-340)

• AAA domain (Cdc48 subfamily) (AAA_2) (605-771)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.795	100	0.458
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.045	100	0.42