Detailed information NTG0327571

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EFD78_RS13990
• Genome accession: NZ_CP033977
• Coordinates: 2762206..2763093 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain P2D15C1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2757206..2768093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EFD78_RS13960 (EFD78_14590)	-	2757225..2757317 (+)	93	WP_010956583.1	hypothetical protein	-
EFD78_RS13965 (EFD78_14595)	-	2757425..2757922 (-)	498	WP_001065268.1	glutathione peroxidase	-
EFD78_RS13970 (EFD78_14600)	-	2757932..2758192 (-)	261	WP_001791974.1	hypothetical protein	-
EFD78_RS13975 (EFD78_14610)	-	2758574..2758687 (-)	114	Protein_2677	hypothetical protein	-
EFD78_RS13980 (EFD78_14615)	-	2759346..2761346 (-)	2001	WP_000776751.1	ABC transporter permease	-
EFD78_RS13985 (EFD78_14620)	-	2761343..2762098 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EFD78_RS13990 (EFD78_14625)	braS	2762206..2763093 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EFD78_RS13995 (EFD78_14630)	braR	2763104..2763769 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EFD78_RS14000 (EFD78_14635)	-	2763795..2763995 (-)	201	WP_000604730.1	hypothetical protein	-
EFD78_RS14005 (EFD78_14640)	-	2764193..2765617 (+)	1425	WP_000953755.1	alkaline phosphatase	-
EFD78_RS14750 (EFD78_14645)	-	2765677..2765778 (-)	102	WP_000731976.1	SE2200 family small protein	-
EFD78_RS14015 (EFD78_14650)	-	2765900..2766355 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EFD78_RS14020 (EFD78_14655)	-	2766600..2767361 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=327571 EFD78_RS13990 WP_000143425.1 2762206..2763093(-) (braS) [Staphylococcus aureus strain P2D15C1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=327571 EFD78_RS13990 WP_000143425.1 2762206..2763093(-) (braS) [Staphylococcus aureus strain P2D15C1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1