Detailed information NTG0326946

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: FNL98_RS05235
• Genome accession: NZ_CP041585
• Coordinates: 888580..891159 (-)
• Length: 859 a.a.
• NCBI ID: WP_003702540.1
• Uniprot ID: Q5F7W9
• Organism: Neisseria gonorrhoeae strain NJ1711654
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 883580..896159

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FNL98_RS05205 (FNL98_05205)	-	883614..884324 (-)	711	WP_003690977.1	phosphoglycolate phosphatase	-
FNL98_RS05215 (FNL98_05215)	-	884719..885938 (+)	1220	Protein_885	Glu/Leu/Phe/Val family dehydrogenase	-
FNL98_RS05220 (FNL98_05220)	-	885998..886804 (-)	807	WP_003690982.1	DUF4198 domain-containing protein	-
FNL98_RS05225 (FNL98_05225)	-	886996..887205 (+)	210	WP_003688192.1	4-oxalocrotonate tautomerase family protein	-
FNL98_RS05230 (FNL98_05230)	-	887294..888508 (+)	1215	WP_003690983.1	pyridoxal phosphate-dependent aminotransferase	-
FNL98_RS05235 (FNL98_05235)	clpC	888580..891159 (-)	2580	WP_003702540.1	ATP-dependent chaperone ClpB	Regulator
FNL98_RS05240 (FNL98_05240)	trpS	891419..892429 (+)	1011	WP_003690986.1	tryptophan--tRNA ligase	-
FNL98_RS05245 (FNL98_05245)	-	892510..893055 (+)	546	WP_003690987.1	hypothetical protein	-
FNL98_RS05255 (FNL98_05255)	-	893372..893716 (+)	345	WP_010358382.1	Ag473 family lipoprotein	-
FNL98_RS05260 (FNL98_05260)	ppx	893926..895434 (-)	1509	WP_103195316.1	exopolyphosphatase	-

Sequence

Protein

• Length: 859 a.a.
• Molecular weight: 95097.51 Da
• Isoelectric Point: 5.3102

>NTDB_id=326946 FNL98_RS05235 WP_003702540.1 888580..891159(-) (clpC) [Neisseria gonorrhoeae strain NJ1711654]
MRYDKLTAKFQQALAEAQSLALAADSSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGE
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
VKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEIDGLQKEYADLDEIWKAEKAISDGAANIKKQID
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGAEEIAEVVSRMTGIPVSKMMEGER
DKLLKMEEVLHRRVVGQNEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSE
YMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNIGSQHIQQMGTQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSD
AALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIKVEADGDRLKFA

Nucleotide

• Length: 2580 bp

>NTDB_id=326946 FNL98_RS05235 WP_003702540.1 888580..891159(-) (clpC) [Neisseria gonorrhoeae strain NJ1711654]
ATGCGATACGACAAATTAACCGCCAAATTCCAACAAGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGCTGCGGACAGCAG
CTATCTGGAAGCAGGTTTCGTACTGAAAGCCCTGCTTGACGACCAAAACAGCGGAGCTGCCGCGCTCTTGGCTCATGCGG
GCGTGAACGTGCCGCAGGTTAAACAGCGTTTGCAGCAGCATTTGAACAGCCTGCCGAAAGTGTCCGGACAAGGTGGTGAG
ATTCTGCCCAGCCGCGAATTGCAGGCGGTGTTGAACCTGATGGACAAAGCGGCAACCAAACGCGGCGATGCCTATATCGC
CAGCGAACTTTTCCTGCTCGCCTTGGTGCAGCAGAACGATGCGGCCGGCAAAATCTTGAAAGAAGCCGGTGCGACCGAAC
AAAACATCAATGCCGCGATCGATGCGGTACGAGGCGGACAAAACGTGAACGATGCGAATGCCGAAGACCAACGCGATGCT
TTGAAAAAATACACGCTCGATCTGACCCAACGCGCCCGAGACGGTAAGCTCGACCCCGTTATCGGTCGTGATGATGAAAT
CCGCCGCGCGATTCAGGTGCTGCAACGCCGCACCAAAAACAACCCCGTGCTGATTGGCGAACCCGGTGTGGGTAAAACCG
CCATCGTCGAAGGTTTGGCGCAACGCATCGTCAACGGCGAAGTACCTGAATCCCTGCGTAACAAACGCCTGCTGGTTTTG
GATTTGGCGGCTTTGATTGCCGGTGCGAAATACCGTGGCGAATTTGAAGAACGCTTGAAAGGCGTATTGAACGATTTGGC
GAAAGACGACGGCAACACCCTGATTTTCATCGATGAAATCCATACTTTGGTCGGCGCGGGCAAAACCGACGGCGCGATGG
ACGCGGGCAATATGTTGAAACCGGCCTTGGCGCGGGGCGAACTGCACTGTATCGGTGCGACTACTTTGGACGAATACCGC
CAATACATCGAAAAAGACGCGGCACTCGAACGCCGTTTCCAAAAAGTATTGGTCGGCGAACCCAGCGTGGAAGACACCAT
CGCTATCCTGCGCGGTTTGCAGGAACGCTATGAAATCCACCACGGCATCGATATTACCGACCCCGCCATTGTTGCCGCAG
CGGAGTTGAGCGACCGCTACATTACCGACCGCTTCCTGCCCGACAAGGCGATTGATTTGATTGACGAAGCTGCCAGCCGT
GTCAAGATGGAAAAAGAAACCAAACCGGAAGCTATGGACAAAATCGACCGCCGTTTGATTCAGCTTCGGATGGAAAAGGC
GCACGTTGAAAAAGAAAAAGACGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAGGAAATCGACGGCTTGCAAAAAG
AATACGCCGATTTGGACGAAATCTGGAAAGCCGAAAAAGCGATTTCAGACGGTGCTGCCAATATTAAGAAACAAATTGAC
GAAGTCAAAATTAAAATCGAACAGGCAAAACGGCAAGGCGATTTGGCACTGGCTTCAAAATTGATGTATGAAGATTTGGA
GCATTTGGAAAAACAGCGTGCAGCCGCCGAACGGGCAGATACGGACAGCACAAAACCGGCAAACAAACTCTTGCGTAATA
ATGTCGGCGCGGAGGAAATCGCAGAAGTGGTTTCCCGTATGACCGGCATCCCCGTGTCAAAAATGATGGAAGGCGAACGC
GACAAACTGCTAAAGATGGAAGAAGTATTGCACCGCCGCGTAGTCGGTCAAAACGAAGCCGTGCGCGCCGTGTCCGATGC
CATCCGCCGCAGCCGCTCCGGCCTTGCCGATCCGAACAAACCTTACGGCAGCTTCCTGTTCTTAGGCCCGACCGGTGTGG
GTAAGACCGAGTTGTGCAAAGCTTTGGCAGGCTTCCTGTTCGACAGCGAAGACCACCTCATCCGCATCGACATGTCCGAA
TACATGGAAAAACACGCCGTTGCCCGCTTAATCGGCGCGCCTCCGGGTTATGTCGGATACGAAGAGGGCGGCTACCTGAC
CGAACAAGTCCGCCGCAAACCGTACAGCGTGATTCTTTTGGACGAAGTGGAAAAAGCCCATCCCGACGTATTCAACATCC
TGCTGCAAGTATTGGATGACGGTCGTTTGACCGACGGACAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATG
ACTTCCAACATCGGCAGCCAGCACATCCAACAAATGGGCACGCAGGACTACGAAGCGGTGAAAGAAGTTGTGATGGAGGA
TGTGAAAGAACATTTCCGTCCGGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCATGGCTTGGATCAGGCCAATA
TCCGCAGTATTGCGAAAATCCAGCTCAAAGGTTTGGAAAAACGTTTGGAAAAACAAAACCTGCGCCTGACTGTTTCCGAT
GCCGCTCTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCGATCCAATCGGA
AATCGAAAACCCGCTGGCCAAAGCCCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAAGGTAGAAGCCGACGGCG
ACAGACTGAAATTTGCCTGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• AAA domain (Cdc48 subfamily) (AAA_2) (601-763)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (769-849)

• AAA lid domain (AAA_lid_9) (342-442)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

3D structure

• AlphaFold DB: Q5F7W9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.581	100	0.456
clpC	Streptococcus pneumoniae TIGR4	39.313	100	0.413
clpC	Streptococcus pneumoniae D39	39.313	100	0.413
clpC	Streptococcus pneumoniae Rx1	39.313	100	0.413
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.616	100	0.403
clpC	Lactococcus lactis subsp. cremoris KW2	46.839	81.024	0.38
clpE	Streptococcus pneumoniae TIGR4	46.921	79.395	0.373
clpE	Streptococcus pneumoniae R6	46.774	79.395	0.371
clpE	Streptococcus pneumoniae D39	46.774	79.395	0.371
clpE	Streptococcus pneumoniae Rx1	46.774	79.395	0.371