Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | EHF40_RS00720 | Genome accession | NZ_CP033907 |
| Coordinates | 109428..110381 (+) | Length | 317 a.a. |
| NCBI ID | WP_021299429.1 | Uniprot ID | A0A660A6K5 |
| Organism | Streptococcus pyogenes strain Duke-Large | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
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Genomic Context
Location: 104428..115381
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EHF40_RS00680 (EHF40_00680) | - | 105255..105620 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| EHF40_RS00685 (EHF40_00685) | comYA | 105713..106651 (+) | 939 | WP_002987773.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| EHF40_RS00690 (EHF40_00690) | comYB | 106587..107621 (+) | 1035 | WP_011054115.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| EHF40_RS00695 (EHF40_00695) | comYC | 107623..107949 (+) | 327 | WP_011528161.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| EHF40_RS00700 (EHF40_00700) | comGD | 107924..108352 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | - |
| EHF40_RS00705 (EHF40_00705) | comGE | 108309..108593 (+) | 285 | WP_011528162.1 | competence type IV pilus minor pilin ComGE | - |
| EHF40_RS00710 (EHF40_00710) | comYF | 108586..109020 (+) | 435 | WP_002992738.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| EHF40_RS00715 (EHF40_00715) | comGG | 109004..109330 (+) | 327 | WP_010921801.1 | competence type IV pilus minor pilin ComGG | - |
| EHF40_RS00720 (EHF40_00720) | comYH | 109428..110381 (+) | 954 | WP_021299429.1 | class I SAM-dependent methyltransferase | Machinery gene |
| EHF40_RS00725 (EHF40_00725) | - | 110440..111636 (+) | 1197 | WP_011528164.1 | acetate kinase | - |
| EHF40_RS00730 (EHF40_00730) | - | 111823..112131 (+) | 309 | WP_011528165.1 | hypothetical protein | - |
| EHF40_RS00735 (EHF40_00735) | proC | 112214..112984 (-) | 771 | WP_002986527.1 | pyrroline-5-carboxylate reductase | - |
| EHF40_RS00740 (EHF40_00740) | pepA | 113032..114099 (-) | 1068 | WP_011528166.1 | glutamyl aminopeptidase | - |
| EHF40_RS00750 (EHF40_00750) | - | 114564..114848 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| EHF40_RS00755 (EHF40_00755) | - | 114845..115162 (+) | 318 | WP_011528167.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 36043.16 Da Isoelectric Point: 4.7205
>NTDB_id=326893 EHF40_RS00720 WP_021299429.1 109428..110381(+) (comYH) [Streptococcus pyogenes strain Duke-Large]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLVPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLVPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=326893 EHF40_RS00720 WP_021299429.1 109428..110381(+) (comYH) [Streptococcus pyogenes strain Duke-Large]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCTAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACCTGAAAAAAGACGGTTTTGCGATTTTTCTGGTACCAGTCAATTTATTGACAAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCTAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACCTGAAAAAAGACGGTTTTGCGATTTTTCTGGTACCAGTCAATTTATTGACAAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
65.506 |
99.685 |
0.653 |
| comYH | Streptococcus mutans UA140 |
65.19 |
99.685 |
0.65 |