Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   EGX82_RS07540 Genome accession   NZ_CP033822
Coordinates   1423045..1425492 (+) Length   815 a.a.
NCBI ID   WP_000020289.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain FDAARGOS_512     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1418045..1430492
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX82_RS07510 (EGX82_07510) ahpC 1418190..1418750 (-) 561 WP_000060536.1 alkyl hydroperoxide reductase subunit C -
  EGX82_RS07515 (EGX82_07515) rpsB 1419027..1419797 (+) 771 WP_000268454.1 30S ribosomal protein S2 -
  EGX82_RS07520 (EGX82_07520) tsf 1419891..1420931 (+) 1041 WP_000808080.1 translation elongation factor Ts -
  EGX82_RS07525 (EGX82_07525) - 1420988..1421792 (+) 805 WP_088181596.1 IS5-like element IS1381A family transposase -
  EGX82_RS07530 (EGX82_07530) - 1421950..1422411 (-) 462 WP_001106578.1 small multi-drug export protein -
  EGX82_RS07535 (EGX82_07535) - 1422584..1423048 (+) 465 WP_000985641.1 CtsR family transcriptional regulator -
  EGX82_RS07540 (EGX82_07540) clpC 1423045..1425492 (+) 2448 WP_000020289.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  EGX82_RS07545 (EGX82_07545) - 1425712..1426203 (-) 492 WP_000586895.1 GNAT family N-acetyltransferase -
  EGX82_RS07550 (EGX82_07550) - 1426217..1426858 (-) 642 WP_000909526.1 deoxynucleoside kinase -
  EGX82_RS07555 (EGX82_07555) dusB 1426979..1427956 (-) 978 WP_000192730.1 tRNA dihydrouridine synthase DusB -
  EGX82_RS07560 (EGX82_07560) hslO 1427940..1428815 (-) 876 WP_000357825.1 Hsp33 family molecular chaperone HslO -
  EGX82_RS07565 (EGX82_07565) - 1428955..1430211 (-) 1257 WP_001285395.1 toxic anion resistance protein -

Sequence

Protein


Download         Length: 815 a.a.        Molecular weight: 90581.13 Da        Isoelectric Point: 6.0603

>NTDB_id=326136 EGX82_RS07540 WP_000020289.1 1423045..1425492(+) (clpC) [Streptococcus agalactiae strain FDAARGOS_512]
MSHYSIKLQEVFRLAQFQAARYESHYLESWHLLLAMVLVHDSVAGLTFAEYESEVAIEEYEAATILALGRAPKEEITNYQ
FLEQSPALKKILKLAENISIVVGAEDVGTEHVLLAMLVNKDLLATRILELVGFRGQDDGESVRMVDLRKALERHAGFTKD
DIKAIYELRNPKKAKSGASFSDMMKPPSTAGDLADFTRDLSQMAVDGEIEPVIGRDKEISRMVQVLSRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGNIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVLVEEPNLEDAYEILLGLKPAYEAFHNVTISDE
AVMTAVKVAHRYLTSKNLPDSAIDLLDEASATVQMMIKKNAPSLLTEVDQAILDDDMKSASKALKASYKGKKRKPIAVTE
DHIMATLSRLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDDAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASHLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDISHDYTAMQKRIMEELKKAYRPEFINRIDEKVVFHS
LSQDNMREVVKIMVKPLILALKDKGMDLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLSELLLANQVKEGQVIK
IGVSKGKLKFDIAKS

Nucleotide


Download         Length: 2448 bp        

>NTDB_id=326136 EGX82_RS07540 WP_000020289.1 1423045..1425492(+) (clpC) [Streptococcus agalactiae strain FDAARGOS_512]
ATGAGTCATTATTCCATAAAATTACAAGAAGTATTCAGATTGGCGCAATTTCAAGCAGCACGCTATGAAAGTCACTATTT
AGAAAGCTGGCATCTTCTTTTAGCAATGGTTTTAGTTCATGATTCAGTAGCTGGTTTGACATTTGCTGAATATGAGTCTG
AAGTTGCAATTGAAGAGTACGAAGCAGCAACAATTTTAGCTTTAGGTAGAGCACCGAAAGAAGAGATTACCAATTATCAA
TTTTTAGAGCAATCACCAGCTTTGAAAAAGATCTTAAAGTTAGCAGAAAATATTAGTATCGTAGTAGGAGCTGAAGATGT
GGGTACTGAACATGTCTTGCTTGCTATGTTGGTTAATAAAGATTTATTAGCCACACGTATCTTAGAGTTAGTTGGCTTTA
GAGGTCAAGACGATGGTGAATCAGTTCGTATGGTTGATTTACGTAAGGCTCTAGAACGTCATGCCGGTTTTACAAAAGAT
GATATCAAAGCAATTTATGAATTACGTAATCCTAAAAAAGCAAAGTCGGGTGCTTCTTTTTCTGATATGATGAAACCACC
GAGTACTGCTGGTGATTTAGCTGATTTCACACGTGATTTATCACAGATGGCGGTTGATGGGGAAATTGAACCTGTTATTG
GGCGTGATAAAGAAATTTCACGTATGGTCCAAGTCTTAAGTCGTAAAACAAAGAATAATCCTGTCTTAGTTGGAGATGCG
GGTGTCGGTAAAACAGCTTTGGCGTACGGTCTAGCACAACGTATTGCTAATGGAAATATTCCTTATGAGCTTAGAGATAT
GCGTGTTCTAGAGTTAGATATGATGAGCGTTGTTGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGTATGAATCAAA
TCATTGCAGATATTGAAGAAGACGGTCATATTATTCTTTTCATTGATGAACTGCATACTATTATGGGTTCTGGCTCTGGT
ATTGATAGCACACTTGATGCTGCTAATATTTTAAAACCAGCTTTGGCCCGAGGCACTTTACGCACTGTTGGAGCAACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAAGATGCTGCTTTATCTCGTCGCTTTGCAAAAGTTTTAGTAGAAGAACCAA
ATCTTGAAGACGCATATGAAATTCTACTTGGATTGAAGCCAGCGTATGAAGCCTTTCATAATGTTACTATTTCAGATGAA
GCAGTTATGACTGCTGTAAAAGTGGCTCATCGTTATTTGACAAGTAAGAATTTACCAGACTCAGCTATAGACTTACTTGA
TGAAGCTTCTGCCACTGTGCAAATGATGATTAAGAAAAATGCTCCTTCGCTTTTAACAGAAGTTGACCAAGCTATTTTAG
ATGATGATATGAAATCTGCTTCTAAAGCTCTAAAAGCAAGTTATAAGGGTAAAAAGCGTAAGCCTATTGCCGTAACAGAA
GATCATATTATGGCAACTCTCAGTCGTCTATCTGGTATTCCTGTTGAAAAATTGACACAAGCTGATAGTAAAAAATACCT
CAATTTAGAAAAAGAATTGCATAAACGTGTTATCGGTCAAGATGATGCAGTTACTGCCATTAGTCGTGCTATCCGTCGCA
ATCAATCTGGCATTCGTACTGGTAAGCGTCCTATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTTGGTAAGACAGAG
TTAGCAAAAGCCTTGGCAGAAGTGTTGTTTGATGATGAATCAGCCCTAATTCGTTTTGATATGTCGGAATATATGGAAAA
ATTCGCAGCTTCTCACCTGAATGGGGCACCTCCAGGTTATGTTGGTTATGATGAAGGAGGAGAGTTGACTGAAAAAGTAC
GCAATAAACCATATTCAGTTTTACTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTTAATGTATTATTACAAGTG
CTTGATGATGGCGTTTTAACAGATAGTCGAGGACGAAAAGTTGATTTTTCAAATACTATAATCATTATGACTTCTAATTT
AGGAGCAACTGCATTACGTGACGATAAAACAGTTGGTTTTGGAGCTAAGGATATCAGCCATGATTATACTGCTATGCAAA
AACGTATTATGGAGGAGCTTAAAAAAGCTTATCGACCAGAGTTTATCAATCGTATTGATGAGAAAGTTGTATTCCATAGT
CTCAGTCAAGATAATATGCGTGAAGTTGTGAAAATTATGGTTAAACCTTTAATTTTAGCGCTTAAAGATAAAGGTATGGA
TCTGAAATTCCAGCCTTCAGCCTTGAAACACTTGGCAGAGGATGGCTATGATATAGAAATGGGTGCTCGTCCACTGCGTA
GAACTATTCAAACGCAAGTAGAGGATCATTTATCAGAACTACTATTGGCAAATCAAGTGAAAGAGGGGCAAGTAATTAAG
ATTGGCGTATCCAAAGGCAAATTGAAATTTGATATTGCAAAATCATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(375-458)

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-801)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(105-132)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-46)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

76.355

99.632

0.761
  clpC Streptococcus thermophilus LMG 18311

72.761

100

0.728
  clpC Streptococcus thermophilus LMD-9

72.638

100

0.726
  clpC Streptococcus pneumoniae TIGR4

68.55

99.877

0.685
  clpC Streptococcus pneumoniae Rx1

68.55

99.877

0.685
  clpC Streptococcus pneumoniae D39

68.55

99.877

0.685
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.558

100

0.496
  clpC Bacillus subtilis subsp. subtilis str. 168

45.608

100

0.465
  clpE Streptococcus mutans UA159

46.238

78.282

0.362
  clpE Streptococcus pneumoniae TIGR4

45.511

79.264

0.361
  clpE Streptococcus pneumoniae Rx1

45.511

79.264

0.361
  clpE Streptococcus pneumoniae D39

45.511

79.264

0.361
  clpE Streptococcus pneumoniae R6

45.511

79.264

0.361

Multiple sequence alignment