Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EGX85_RS11055 Genome accession   NZ_CP033814
Coordinates   2227258..2227974 (-) Length   238 a.a.
NCBI ID   WP_011275301.1    Uniprot ID   Q4L7S3
Organism   Staphylococcus haemolyticus strain FDAARGOS_517     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2222258..2232974
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX85_RS11035 (EGX85_11060) - 2222300..2223544 (+) 1245 WP_033079908.1 ammonium transporter -
  EGX85_RS11040 (EGX85_11065) - 2223644..2224603 (+) 960 WP_033079907.1 LacI family DNA-binding transcriptional regulator -
  EGX85_RS11045 (EGX85_11070) - 2224688..2226172 (+) 1485 WP_033079906.1 sucrose-6-phosphate hydrolase -
  EGX85_RS11050 (EGX85_11075) - 2226176..2227141 (+) 966 WP_016931059.1 carbohydrate kinase -
  EGX85_RS11055 (EGX85_11080) agrA 2227258..2227974 (-) 717 WP_011275301.1 quorum-sensing response regulator AgrA Regulator
  EGX85_RS11060 (EGX85_11085) agrC 2227993..2229276 (-) 1284 WP_033079905.1 quorum-sensing sensor histidine kinase AgrC -
  EGX85_RS11065 (EGX85_11090) agrD 2229303..2229443 (-) 141 WP_033079904.1 cyclic lactone autoinducer peptide AgrD -
  EGX85_RS11070 (EGX85_11095) - 2229446..2230012 (-) 567 WP_033079903.1 accessory gene regulator AgrB -
  EGX85_RS11075 (EGX85_11100) - 2230742..2231527 (-) 786 WP_011275305.1 carbon-nitrogen family hydrolase -
  EGX85_RS11080 (EGX85_11105) - 2231720..2232343 (-) 624 WP_011275306.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27801.74 Da        Isoelectric Point: 5.2189

>NTDB_id=326001 EGX85_RS11055 WP_011275301.1 2227258..2227974(-) (agrA) [Staphylococcus haemolyticus strain FDAARGOS_517]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEVIEKSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPSQLQSRIIDCLETAHTRLKLLSKESTVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVVNRHNIESIDSKERIVNFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=326001 EGX85_RS11055 WP_011275301.1 2227258..2227974(-) (agrA) [Staphylococcus haemolyticus strain FDAARGOS_517]
ATGAAAATATTCATTTGTGAAGATGATGTAAAACAACGCGAAAATATGGTTTCAATTATTAATAATTACATTATGATTGA
AGAAAAACCTATGGAGATTGCGCTTGCAACAGACGATCCTTATGAAGTCATTGAAAAATCTAAAGAGATGAATGATGTCG
GATGTTACTTTCTAGATATTCAATTAGAGGCTGATATCAACGGTATTAAATTAGGTAGTGAAATTCGTAAGTATGACCCA
ATTGGGAATATCATATTCGTTACAAGTCATAGTGAGTTAACGTACCTAACCTTTGTTTACAAAGTGTCAGCGATGGATTT
TATCTTTAAAGATGATCCAAGCCAATTACAGTCCAGAATTATTGATTGCTTAGAAACTGCACATACCCGCTTAAAATTAT
TATCTAAAGAAAGTACTGTTGAGACGATTGAATTGAAACGAGGAAGTAATTCAATTTATGTTCAATATGATGACGTAATG
TTTTTCGAATCATCTACAAAATCACATCGGTTAATCGCACATTTAGATAATCGTCAAATTGAGTTCTATGGCAATTTAAA
AGAACTTGCACAACTTGATGAGCGGTTCTTTAGATGTCACAACAGCTTCGTTGTTAATAGACATAATATTGAATCCATAG
ATTCAAAAGAACGTATTGTCAATTTTAAAAACGGTGAGCACTGTTTTGCTTCCGTTCGTAATGTAAAAAAAATATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4L7S3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878

Multiple sequence alignment