Detailed information NTG0325942

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EGX96_RS07785
• Genome accession: NZ_CP033810
• Coordinates: 1451674..1452747 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus sp. FDAARGOS_520
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1446674..1457747

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX96_RS07750 (EGX96_07750)	-	1447567..1448631 (+)	1065	WP_000021304.1	MmcQ/YjbR family DNA-binding protein	-
EGX96_RS07755 (EGX96_07755)	asnA	1448745..1449737 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
EGX96_RS07760 (EGX96_07760)	-	1449782..1450231 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
EGX96_RS07770 (EGX96_07770)	rsmD	1450361..1450900 (+)	540	WP_001266829.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EGX96_RS07775 (EGX96_07775)	-	1450912..1451202 (+)	291	WP_000384889.1	hypothetical protein	-
EGX96_RS07780 (EGX96_07780)	coaD	1451199..1451684 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
EGX96_RS07785 (EGX96_07785)	sepM	1451674..1452747 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
EGX96_RS07790 (EGX96_07790)	-	1452822..1454154 (+)	1333	Protein_1405	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
EGX96_RS07795 (EGX96_07795)	-	1454223..1454801 (+)	579	WP_001224500.1	YutD-like domain-containing protein	-
EGX96_RS07800 (EGX96_07800)	rlmN	1454852..1455958 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
EGX96_RS07805 (EGX96_07805)	-	1455958..1456473 (+)	516	WP_000919802.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=325942 EGX96_RS07785 WP_000796095.1 1451674..1452747(+) (sepM) [Streptococcus sp. FDAARGOS_520]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=325942 EGX96_RS07785 WP_000796095.1 1451674..1452747(+) (sepM) [Streptococcus sp. FDAARGOS_520]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658