Detailed information NTG0325894

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EGX72_RS09635
• Genome accession: NZ_CP033809
• Coordinates: 1813294..1814367 (-)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus sp. FDAARGOS_521
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1808294..1819367

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX72_RS09615 (EGX72_09605)	-	1809568..1810083 (-)	516	WP_000919802.1	VanZ family protein	-
EGX72_RS09620 (EGX72_09610)	rlmN	1810083..1811189 (-)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
EGX72_RS09625 (EGX72_09615)	-	1811240..1811818 (-)	579	WP_001224500.1	YutD-like domain-containing protein	-
EGX72_RS09630 (EGX72_09620)	-	1811887..1813219 (-)	1333	Protein_1800	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
EGX72_RS09635 (EGX72_09625)	sepM	1813294..1814367 (-)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
EGX72_RS09640 (EGX72_09630)	coaD	1814357..1814842 (-)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
EGX72_RS09645 (EGX72_09635)	-	1814839..1815129 (-)	291	WP_000384889.1	hypothetical protein	-
EGX72_RS09650 (EGX72_09640)	rsmD	1815141..1815680 (-)	540	WP_001266829.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EGX72_RS09660 (EGX72_09650)	-	1815810..1816259 (+)	450	WP_000592263.1	thiol reductase thioredoxin	-
EGX72_RS09665 (EGX72_09655)	asnA	1816304..1817296 (-)	993	WP_000748011.1	aspartate--ammonia ligase	-
EGX72_RS09670 (EGX72_09660)	-	1817410..1818474 (-)	1065	WP_000021302.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=325894 EGX72_RS09635 WP_000796095.1 1813294..1814367(-) (sepM) [Streptococcus sp. FDAARGOS_521]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=325894 EGX72_RS09635 WP_000796095.1 1813294..1814367(-) (sepM) [Streptococcus sp. FDAARGOS_521]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658