Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   EGX72_RS06955 Genome accession   NZ_CP033809
Coordinates   1288597..1289910 (+) Length   437 a.a.
NCBI ID   WP_000042580.1    Uniprot ID   A0AAW3HV66
Organism   Streptococcus sp. FDAARGOS_521     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1283597..1294910
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX72_RS06935 (EGX72_06930) pstB 1283631..1284389 (+) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -
  EGX72_RS06940 (EGX72_06935) phoU 1284423..1285076 (+) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  EGX72_RS06945 (EGX72_06940) - 1285222..1287771 (+) 2550 WP_123957747.1 M1 family metallopeptidase -
  EGX72_RS06950 (EGX72_06945) ciaR 1287933..1288613 (+) 681 WP_000590620.1 response regulator transcription factor Regulator
  EGX72_RS06955 (EGX72_06950) ciaH 1288597..1289910 (+) 1314 WP_000042580.1 cell wall metabolism sensor histidine kinase WalK Regulator
  EGX72_RS06960 (EGX72_06955) - 1289999..1290331 (+) 333 WP_000402075.1 putative DNA-binding protein -
  EGX72_RS06965 (EGX72_06960) ffh 1290349..1291914 (+) 1566 WP_000863589.1 signal recognition particle protein -
  EGX72_RS06970 (EGX72_06965) - 1291981..1292667 (+) 687 WP_000280308.1 SatD family protein -
  EGX72_RS06975 (EGX72_06970) - 1292657..1293430 (+) 774 WP_000622398.1 DUF3307 domain-containing protein -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49708.14 Da        Isoelectric Point: 9.4961

>NTDB_id=325877 EGX72_RS06955 WP_000042580.1 1288597..1289910(+) (ciaH) [Streptococcus sp. FDAARGOS_521]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDIILFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRTPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLITQENGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=325877 EGX72_RS06955 WP_000042580.1 1288597..1289910(+) (ciaH) [Streptococcus sp. FDAARGOS_521]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTATTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAACATCTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCCCTAGCTGTCTTACAAAATCGCCTAGAAACGCTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCACCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATCCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGGTTTGGCCTC
GGCCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.14

98.169

0.59
  ciaH Streptococcus pneumoniae Rx1

51.781

96.339

0.499
  ciaH Streptococcus pneumoniae D39

51.781

96.339

0.499
  ciaH Streptococcus pneumoniae R6

51.781

96.339

0.499
  ciaH Streptococcus pneumoniae TIGR4

51.781

96.339

0.499

Multiple sequence alignment