Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EGX95_RS04855 Genome accession   NZ_CP033795
Coordinates   493083..493766 (+) Length   227 a.a.
NCBI ID   WP_000350710.1    Uniprot ID   Q81TR3
Organism   Bacillus sp. FDAARGOS_527     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 488083..498766
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX95_RS04835 (EGX95_04835) - 489153..490799 (+) 1647 WP_000728616.1 peptide ABC transporter substrate-binding protein -
  EGX95_RS04840 (EGX95_04840) - 490828..491031 (-) 204 WP_000559978.1 hypothetical protein -
  EGX95_RS04845 (EGX95_04845) spx 491624..492019 (+) 396 WP_000258267.1 transcriptional regulator Spx -
  EGX95_RS04850 (EGX95_04850) - 492069..492743 (-) 675 WP_000362603.1 TerC family protein -
  EGX95_RS04855 (EGX95_04855) mecA 493083..493766 (+) 684 WP_000350710.1 adaptor protein MecA Regulator
  EGX95_RS04860 (EGX95_04860) - 493839..495383 (+) 1545 WP_000799204.1 cardiolipin synthase -
  EGX95_RS04865 (EGX95_04865) - 495464..496708 (+) 1245 WP_000612264.1 competence protein CoiA -
  EGX95_RS04870 (EGX95_04870) pepF 496759..498585 (+) 1827 WP_000003390.1 oligoendopeptidase F Regulator

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26966.00 Da        Isoelectric Point: 3.9822

>NTDB_id=325743 EGX95_RS04855 WP_000350710.1 493083..493766(+) (mecA) [Bacillus sp. FDAARGOS_527]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=325743 EGX95_RS04855 WP_000350710.1 493083..493766(+) (mecA) [Bacillus sp. FDAARGOS_527]
TTGGATATTGAAAGAATTAATGATCATACGATGAAATTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCG
TGAGGAAATTTGGTATGACCGCGAAAGAAGCGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGGCCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAACTT
TCAAAGGATGGACAAAAGCTAGAACTACCAATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGTATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAGGAACAAGCAGGTACAAACTTTAACGAAGATGGTACGTTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGGACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAAGAAGAAATTGATCGCATTTTAAG
CATTGTTTTAGAATACGGGGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81TR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

56.14

100

0.564

Multiple sequence alignment