Detailed information NTG0325739

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EGX95_RS04745
• Genome accession: NZ_CP033795
• Coordinates: 469864..472464 (+)
• Length: 866 a.a.
• NCBI ID: WP_000365370.1
• Uniprot ID: A0A5M9GXY4
• Organism: Bacillus sp. FDAARGOS_527
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 464864..477464

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX95_RS04710 (EGX95_04710)	prsA	465623..466480 (-)	858	WP_001214227.1	peptidylprolyl isomerase PrsA	-
EGX95_RS04715 (EGX95_04715)	-	466610..466741 (-)	132	WP_001120845.1	DUF3941 domain-containing protein	-
EGX95_RS04720 (EGX95_04720)	-	466842..467699 (+)	858	WP_000364453.1	YitT family protein	-
EGX95_RS04725 (EGX95_04725)	-	467725..467922 (-)	198	WP_000527391.1	DUF3813 domain-containing protein	-
EGX95_RS04730 (EGX95_04730)	-	467923..468063 (-)	141	WP_000516816.1	hypothetical protein	-
EGX95_RS04735 (EGX95_04735)	-	468169..468978 (-)	810	WP_001041235.1	Cof-type HAD-IIB family hydrolase	-
EGX95_RS04740 (EGX95_04740)	-	469473..469652 (+)	180	WP_000531421.1	YjzC family protein	-
EGX95_RS04745 (EGX95_04745)	clpC	469864..472464 (+)	2601	WP_000365370.1	ATP-dependent chaperone ClpB	Regulator
EGX95_RS04750 (EGX95_04750)	-	472502..472684 (-)	183	WP_001211114.1	YjzD family protein	-
EGX95_RS04755 (EGX95_04755)	-	472841..473575 (+)	735	WP_000028698.1	hydrolase	-
EGX95_RS04760 (EGX95_04760)	-	473605..474477 (+)	873	WP_000486161.1	NAD-dependent epimerase/dehydratase family protein	-
EGX95_RS04765 (EGX95_04765)	comZ	474531..474707 (+)	177	WP_009879752.1	ComZ family protein	Regulator
EGX95_RS04770 (EGX95_04770)	fabH	475286..476218 (+)	933	WP_001100543.1	beta-ketoacyl-ACP synthase III	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 97480.45 Da
• Isoelectric Point: 5.1561

>NTDB_id=325739 EGX95_RS04745 WP_000365370.1 469864..472464(+) (clpC) [Bacillus sp. FDAARGOS_527]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGAEGLIKKKPSVTGSGAE
AGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDINQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASGMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEDDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide

• Length: 2601 bp

>NTDB_id=325739 EGX95_RS04745 WP_000365370.1 469864..472464(+) (clpC) [Bacillus sp. FDAARGOS_527]
ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCTCAATCTTTAGCGGTATCTCATCATCATCA
AGAAGTAGATACTGTTCATCTCTTGTTTACATTATTAGAAGAGCAAGATGGGCTAGCAGTACGTATTTTTCAAAAAATGA
ATGTCGATATAGAAGCGTTAAAACAAGGTGCTGAAGGTTTAATTAAGAAAAAGCCCTCTGTAACGGGAAGCGGTGCAGAA
GCAGGTAAATTATATATAACAGGTGCTTTGCAACAACTGCTTGTAAGAGCAGGAAAAGAAGCAGAAAAATTGCAAGATGA
TTACATTTCAGTTGAACATGTATTACTTGCTTTTACTGAAGAAAAAGGCGATATAAACCAATTATTTACAAGATTTCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGTCGTGATTTAGTGGCGGAAGTAAGAGCGGGGAAAATTGACCCTGTTATCGGCCGCGA
TAGTGAAATTCGCCGCGTAATCCGCATTCTTTCACGTAAAACGAAAAACAACCCAGTTTTAATTGGTGAACCAGGTGTTG
GTAAAACAGCAATTGTTGAAGGGTTAGCACAGCGTATTGTGAAAAAGGATGTACCTGAAGGATTAAAAGATAGAACAATT
TTTGCATTAGATATGAGTGCGCTTGTAGCTGGAGCGAAATTCCGCGGTGAGTTTGAGGAGCGTCTCCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGTCGTATTTTACTATTCATTGATGAACTTCACACAATCGTCGGCGCTGGTAAAACAGAAG
GCGCAATGGATGCAGGAAATATGTTAAAACCGATGCTTGCGCGTGGTGAACTGCATTGTATCGGGGCGACGACGTTAGAT
GAATATCGTAAATATATTGAGAAAGATCCAGCGCTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA
AGATACAATTTCCATTTTACGTGGTTTAAAAGAGCGCTTTGAAATTTATCACGGTGTAAATATTCATGACCGCGCGATTG
TAGCAGCATCAGTTTTATCAGATCGATATATTTCGGACCGTTTCTTACCAGATAAAGCAATTGATCTTGTCGATGAAGCG
TGTGCAACAATTCGTACAGAAATCGATTCTATGCCGACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGCTAGAAAT
TGAAGAAGCGGCTCTTGGAAAAGAAAAGGACTTTGGTAGCCAAGAACGTCTAAAAACGTTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCAAGTGGTATGAGAGCCAAATGGGAGAAAGAAAAAGAAGATATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAGCGTCTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAGAGCAGCGGAACTTCGCCACGG
AAAAATTCCTGCAATTGAAAAAGAGTTAAAAGAAGCAGAAGAAATGGGCGCGCATAATAAACAAGAAAATCGTTTATTAC
GTGAGGAAGTAAGTGAAGAAGAGATTGCTGATATTGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAAGGT
GAACGTGAGAAATTATTACGATTAGAGCAAATTTTATCAGAGCGTGTCATCGGACAAGAGGAAGCGGTAAGCTTAGTATC
AGACGCAGTTCTTCGTGCGCGCGCAGGTATCAAAGACCCGAACCGTCCGATTGGTTCCTTCATTTTCTTAGGACCTACTG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCGCAGTCATTATTCGATAGTGAAGAACAAATGATTCGTATTGATATG
TCTGAGTATATGGAGAAACACGCGGTGTCACGCTTAATTGGTGCGCCTCCTGGATATGTTGGATATGAAGAGGGCGGTCA
ATTAACAGAAGCGGTAAGACGTAAACCGTATTCGGTTATTTTATTAGACGAAATCGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGACGGTCGCATTACAGATTCGCAAGGACGTACAGTAGACTTTAAAAACACAGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTATTAGATGGATTAGAAGATGATGGCTCCATTAAAGAGGAATCAAGAGA
GCTTGTAATGGGACAATTAAGAGGACATTTCCGACCAGAGTTTTTAAACCGTGTCGACGAAATTATTTTATTCAAACCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGTTTAGCTGACCGTCACATTACG
GTAGAATTAACAGACGCAGCGAAAGAGTTTGTTGTCGAAGCTGGCTTCGATCCGATGTACGGAGCCCGTCCATTAAAAAG
ATATGTACAGCGTCAAGTTGAGACGAAATTAGCGAGAGAATTAATTGCAGGAACGATTACTGATAATAGTCACGTAGTTG
TTGATGTAGAAAATAACGAATTAGTCGTTCATGTGAAGTAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-148)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-66)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-854)

• AAA lid domain (AAA_lid_9) (345-447)

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-339)

3D structure

• AlphaFold DB: A0A5M9GXY4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.657	100	0.482
clpC	Lactococcus lactis subsp. cremoris KW2	47.199	82.448	0.389