Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EGX58_RS08400 Genome accession   NZ_CP033732
Coordinates   1670196..1670912 (-) Length   238 a.a.
NCBI ID   WP_002455088.1    Uniprot ID   -
Organism   Staphylococcus hominis strain FDAARGOS_575     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1665196..1675912
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX58_RS08380 (EGX58_08390) - 1665864..1666088 (+) 225 WP_002448268.1 sulfurtransferase TusA family protein -
  EGX58_RS08385 (EGX58_08395) - 1666199..1667443 (+) 1245 WP_002448259.1 ammonium transporter -
  EGX58_RS11555 - 1667549..1667616 (+) 68 Protein_1613 LacI family DNA-binding transcriptional regulator -
  EGX58_RS08390 (EGX58_08400) - 1667698..1669185 (+) 1488 WP_103288021.1 sucrose-6-phosphate hydrolase -
  EGX58_RS08395 (EGX58_08405) - 1669186..1670157 (+) 972 WP_103288022.1 carbohydrate kinase family protein -
  EGX58_RS08400 (EGX58_08410) agrA 1670196..1670912 (-) 717 WP_002455088.1 quorum-sensing response regulator AgrA Regulator
  EGX58_RS08405 (EGX58_08415) agrC 1670925..1672214 (-) 1290 WP_049431162.1 quorum-sensing sensor histidine kinase AgrC -
  EGX58_RS08410 (EGX58_08420) agrD 1672238..1672378 (-) 141 WP_049417668.1 cyclic lactone autoinducer peptide AgrD -
  EGX58_RS08415 (EGX58_08425) - 1672381..1672947 (-) 567 WP_002455090.1 accessory gene regulator AgrB -
  EGX58_RS08420 (EGX58_08430) - 1673649..1674434 (-) 786 WP_002488076.1 carbon-nitrogen family hydrolase -
  EGX58_RS08425 (EGX58_08435) - 1674565..1675188 (-) 624 WP_002448275.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27858.75 Da        Isoelectric Point: 5.2104

>NTDB_id=325156 EGX58_RS08400 WP_002455088.1 1670196..1670912(-) (agrA) [Staphylococcus hominis strain FDAARGOS_575]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEIIEQSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPNQLKTRIIDCIETAHTRLKLLSKESNVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDDRFFRCHNSFVVNRHNIDSVDSKERIVTFRNGEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=325156 EGX58_RS08400 WP_002455088.1 1670196..1670912(-) (agrA) [Staphylococcus hominis strain FDAARGOS_575]
ATGAAAATATTCATTTGTGAAGACGATGTGAAACAACGTGAAAATATGGTTTCAATTATTAACAACTATATAATGATTGA
AGAAAAACCGATGGAAATAGCGTTAGCGACAGATGATCCTTATGAAATTATTGAACAGTCAAAAGAAATGAATGATGTTG
GATGTTATTTTTTAGATATACAATTGGAAGCTGATATTAACGGTATTAAACTTGGAAGTGAAATTCGAAAGTATGATCCT
ATTGGGAATATCATCTTTGTTACAAGTCATAGTGAACTCACTTACCTAACATTTGTCTATAAGGTATCTGCAATGGATTT
TATTTTTAAAGATGATCCTAATCAACTAAAAACGCGAATAATAGATTGCATTGAAACTGCTCATACACGTTTAAAATTAC
TTTCAAAAGAAAGCAATGTTGAAACAATTGAATTAAAGCGTGGTAGCAATTCAATATATGTACAATATGATGATGTCATG
TTCTTTGAATCGTCTACAAAATCCCATCGTTTAATTGCACATCTTGATAACCGTCAGATTGAATTCTACGGAAATCTTAA
AGAATTAGCACAACTCGATGATCGTTTTTTCAGATGTCACAATAGTTTTGTTGTAAATCGTCATAATATCGATTCAGTCG
ATTCTAAAGAACGAATTGTAACTTTCAGAAATGGTGAGCATTGCTATGCCTCTGTACGTAATGTTAAAAAGATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874

Multiple sequence alignment