Detailed information NTG0325148

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: EGX58_RS04525
• Genome accession: NZ_CP033732
• Coordinates: 876757..878382 (-)
• Length: 541 a.a.
• NCBI ID: WP_002486185.1
• Uniprot ID: -
• Organism: Staphylococcus hominis strain FDAARGOS_575
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	876757..879753	876757..878382	within	0

Gene organization within MGE regions

Location: 876757..879753

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX58_RS04525 (EGX58_04535)	ccrB	876757..878382 (-)	1626	WP_002486185.1	cassette chromosome recombinase CcrB	Machinery gene
EGX58_RS04530 (EGX58_04540)	ccrA	878404..879753 (-)	1350	WP_002486190.1	cassette chromosome recombinase CcrA	Machinery gene

Sequence

Protein

• Length: 541 a.a.
• Molecular weight: 62467.41 Da
• Isoelectric Point: 9.7263

>NTDB_id=325148 EGX58_RS04525 WP_002486185.1 876757..878382(-) (ccrB) [Staphylococcus hominis strain FDAARGOS_575]
MDKMKKKLVGGYIRVSTERQVEGYSIEGQITQIEQYCQFNGYELVDIYADRGISGKSMNRPELQRMLNDAKNGKLDCVMV
YKTNRLARNTSDLLTIVEELHRQNVEFFSLSERMEVKNSTGKLMLQILASFSEFERNTILENIYTGQRQRALEGYYQGNL
PLGYNNIPDNKKELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYIGKIQFAKY
KDWNDKRRKGLNDKPVIAEGKHTPIISQDLWDKVQARKKQVSKKPQVHGKGTNLLTGIIVCEKCGAAYAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQENQVDVAALNHDIAYKQQQFDE
INTKLKNLVQTIEDNPDLTSALKPTIHQYETQLNDITNQMNQLKHQQNQEKPSYDTKQIAALLQRIFQNIEFMDKSQLKA
LYLTVIDRIDIRKDENHKKQFYVTLKLNNEIIKQLFNNNNLDEVLLSTSSLFLPQTLYFQI

Nucleotide

• Length: 1626 bp

>NTDB_id=325148 EGX58_RS04525 WP_002486185.1 876757..878382(-) (ccrB) [Staphylococcus hominis strain FDAARGOS_575]
ATGGATAAAATGAAGAAAAAGCTTGTAGGAGGCTACATTCGCGTATCCACAGAGAGACAAGTAGAGGGTTATAGCATCGA
GGGACAAATTACACAAATAGAGCAATATTGCCAATTTAATGGCTATGAACTCGTTGATATATATGCAGATCGGGGTATAT
CAGGAAAATCTATGAACCGTCCTGAATTACAGCGCATGTTAAATGATGCTAAAAATGGAAAATTAGACTGTGTTATGGTT
TATAAAACAAATCGTTTGGCACGTAATACTTCCGATTTACTTACAATCGTCGAAGAACTTCATCGCCAAAATGTTGAATT
TTTTAGCTTGTCTGAACGCATGGAAGTCAAAAATTCAACAGGCAAGTTAATGCTCCAGATACTTGCAAGTTTTTCCGAAT
TTGAAAGAAATACAATTTTAGAGAACATTTACACTGGACAACGTCAAAGAGCTTTAGAGGGCTATTATCAAGGCAATCTT
CCATTAGGATATAATAACATACCTGATAATAAAAAAGAATTAATGATTAATCAACATGAAGCCAATATTGTGAAGTATAT
CTTTGAATCTTACGCTAAAGGTCATGGCTATCGTAAAATTGCCAATGCACTCAATCATAAAGGTTATGTCACTAAGAAGG
GTAATCCATTTAGTATTTCAGCTGTTACTTATATTCTCTCAAACCCATTCTATATTGGTAAAATTCAATTCGCAAAATAC
AAAGATTGGAATGATAAACGACGTAAAGGATTAAACGATAAGCCAGTAATCGCTGAAGGTAAACACACGCCTATTATTAG
TCAAGATTTATGGGATAAAGTGCAAGCACGTAAGAAGCAAGTAAGCAAAAAGCCACAGGTACATGGTAAAGGGACAAATC
TGTTAACTGGAATAATTGTCTGCGAAAAATGTGGTGCAGCATATGCAGCTTCAAATACAACCAACACACTCAAAGACGGT
ACTAAAAAACGCATTCGGTATTATTCATGTAGTAACTTTCGTAACAAAGGATCAAAGGTATGTTCAGCCAATAGTGTTAG
AGCTGATGTTATCGAAAAGTATGTTATGGATCAAATACTCGAAATAGTCAAAAGTGATAAAGTTATCAAACAAGTTGTCG
AACGTGTTAATCAAGAAAATCAAGTCGATGTAGCTGCGCTCAATCATGATATCGCTTATAAACAACAACAATTTGATGAA
ATTAACACTAAACTTAAAAATCTAGTTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCATTCA
TCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAGCTCAAGCACCAACAAAATCAAGAGAAACCATCTT
ATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATTCATGGATAAATCACAGCTCAAAGCT
TTGTACCTAACGGTTATTGACCGTATTGATATTCGTAAAGACGAGAATCATAAAAAACAATTCTATGTCACTCTCAAGCT
CAATAATGAAATTATTAAACAACTTTTTAATAATAACAATCTAGACGAAGTGCTCCTCAGCACTTCGTCTTTGTTTTTGC
CTCAAACACTCTACTTTCAAATATAA

Domains

Predicted by InterproScan.

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (294-359)

• Recombinase (Recombinase) (179-279)

• Resolvase, N terminal domain (Resolvase) (11-154)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	80.258	100	0.804