Detailed information NTG0324634

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: FIV54_RS01170
• Genome accession: NZ_CP041037
• Coordinates: 243554..245659 (-)
• Length: 701 a.a.
• NCBI ID: WP_001838096.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain NP66
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 238554..250659

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIV54_RS01155 (FIV54_01155)	-	241069..241296 (+)	228	WP_000932073.1	FeoA family protein	-
FIV54_RS01160 (FIV54_01160)	feoB	241308..243302 (+)	1995	WP_000432934.1	ferrous iron transport protein B	-
FIV54_RS01165 (FIV54_01165)	-	243315..243485 (+)	171	WP_000111118.1	FeoB-associated Cys-rich membrane protein	-
FIV54_RS01170 (FIV54_01170)	clpE	243554..245659 (-)	2106	WP_001838096.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
FIV54_RS01175 (FIV54_01175)	-	246068..246589 (+)	522	WP_000455987.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
FIV54_RS01180 (FIV54_01180)	-	246759..247925 (-)	1167	WP_000151982.1	hydroxymethylglutaryl-CoA synthase	-
FIV54_RS01185 (FIV54_01185)	-	248179..249459 (+)	1281	WP_001180324.1	hydroxymethylglutaryl-CoA reductase, degradative	-
FIV54_RS01190 (FIV54_01190)	-	249597..250028 (-)	432	WP_000455861.1	CHAP domain-containing protein	-
FIV54_RS01195 (FIV54_01195)	-	250418..250636 (-)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77845.23 Da
• Isoelectric Point: 4.6290

>NTDB_id=324634 FIV54_RS01170 WP_001838096.1 243554..245659(-) (clpE) [Staphylococcus aureus strain NP66]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFHQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Nucleotide

• Length: 2106 bp

>NTDB_id=324634 FIV54_RS01170 WP_001838096.1 243554..245659(-) (clpE) [Staphylococcus aureus strain NP66]
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCACCAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAACGGCAATTAT
TTAGAACAAATTGGTCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTCTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAATCAAAGACAAAGAAATTATTTCTGTA
GACATTTCATCATTAGAAGCTGGAACGCAATATCGTGGTGCTTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACGCTGAAGAAAAAGATATTAT
GCACGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTGCAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGGACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGCTATGATGAAGAATTAGGTGCACGTCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTATTATCTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.834	91.726	0.448
clpC	Lactococcus lactis subsp. cremoris KW2	45.662	93.723	0.428
clpE	Streptococcus pneumoniae Rx1	48.298	88.017	0.425
clpE	Streptococcus pneumoniae D39	48.298	88.017	0.425
clpE	Streptococcus pneumoniae R6	48.298	88.017	0.425
clpE	Streptococcus pneumoniae TIGR4	48.298	88.017	0.425
clpC	Bacillus subtilis subsp. subtilis str. 168	44.564	93.153	0.415
clpC	Streptococcus thermophilus LMD-9	44.392	90.3	0.401
clpC	Streptococcus thermophilus LMG 18311	44.076	90.3	0.398
clpC	Streptococcus pneumoniae TIGR4	44.175	88.16	0.389
clpC	Streptococcus pneumoniae Rx1	44.175	88.16	0.389
clpC	Streptococcus pneumoniae D39	44.175	88.16	0.389
clpC	Streptococcus mutans UA159	43.577	87.732	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.536	88.873	0.378