Detailed information NTG0324415

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: FIU24_RS29745
• Genome accession: NZ_CP041013
• Coordinates: 6143414..6144058 (+)
• Length: 214 a.a.
• NCBI ID: WP_003085214.1
• Uniprot ID: A0A0H2ZLY6
• Organism: Pseudomonas aeruginosa strain FDAARGOS_610
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 6138414..6149058

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIU24_RS29720 (FIU24_29720)	-	6138906..6140387 (-)	1482	WP_003101642.1	AAA family ATPase	-
FIU24_RS29725 (FIU24_29725)	-	6140466..6140804 (+)	339	WP_003085225.1	histidine triad nucleotide-binding protein	-
FIU24_RS29730 (FIU24_29730)	coq7	6140904..6141551 (+)	648	WP_003085224.1	2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase	-
FIU24_RS29735 (FIU24_29735)	speD	6141606..6142400 (-)	795	WP_003085223.1	adenosylmethionine decarboxylase	-
FIU24_RS29740 (FIU24_29740)	-	6142720..6143142 (-)	423	WP_003085219.1	OsmC family protein	-
FIU24_RS29745 (FIU24_29745)	crp	6143414..6144058 (+)	645	WP_003085214.1	cAMP-activated global transcriptional regulator CRP	Regulator
FIU24_RS29750 (FIU24_29750)	trpC	6144120..6144956 (-)	837	WP_003085205.1	indole-3-glycerol phosphate synthase TrpC	-
FIU24_RS29755 (FIU24_29755)	trpD	6144953..6146002 (-)	1050	WP_003085203.1	anthranilate phosphoribosyltransferase	-
FIU24_RS29760 (FIU24_29760)	-	6146004..6146609 (-)	606	WP_003101640.1	aminodeoxychorismate/anthranilate synthase component II	-
FIU24_RS29765 (FIU24_29765)	-	6147028..6147258 (-)	231	WP_003118930.1	hypothetical protein	-
FIU24_RS29770 (FIU24_29770)	-	6147255..6147557 (-)	303	WP_003113177.1	hypothetical protein	-
FIU24_RS29775 (FIU24_29775)	-	6147557..6148609 (-)	1053	WP_004352271.1	pyocin knob domain-containing protein	-
FIU24_RS29780 (FIU24_29780)	-	6148705..6148935 (-)	231	WP_004352270.1	hypothetical protein	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24225.01 Da
• Isoelectric Point: 8.0525

>NTDB_id=324415 FIU24_RS29745 WP_003085214.1 6143414..6144058(+) (crp) [Pseudomonas aeruginosa strain FDAARGOS_610]
MVAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK
EGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD
AMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGTR

Nucleotide

• Length: 645 bp

>NTDB_id=324415 FIU24_RS29745 WP_003085214.1 6143414..6144058(+) (crp) [Pseudomonas aeruginosa strain FDAARGOS_610]
ATGGTAGCTATTACCCACACACCCAAACTCAAACACCTAGACAAGCTGCTCGCACACTGTCACCGCCGCCGCTACACCGC
AAAGAGCACCATCATCTATGCCGGCGATCGCTGCGAAACGCTGTTCTTCATCATCAAGGGTTCGGTCACCATCCTCATCG
AGGACGACGACGGCCGCGAAATGATCATCGGCTACCTCAACAGCGGTGATTTCTTCGGCGAGCTGGGATTGTTCGAAAAG
GAAGGCAGCGAACAGGAACGCAGCGCCTGGGTTCGCGCCAAGGTGGAATGCGAAGTCGCCGAGATCAGCTATGCGAAGTT
CCGCGAACTGTCGCAGCAGGACTCGGAGATCCTCTACACCCTCGGCAGCCAGATGGCCGACCGCCTGCGCAAGACCACCC
GCAAGGTGGGCGACCTGGCCTTCCTCGACGTCACCGGACGCGTCGCCCGCACCTTGCTGGACCTGTGCCAGCAACCGGAC
GCCATGACCCACCCGGACGGCATGCAGATCAAGATCACCCGCCAGGAGATCGGCCGGATCGTCGGCTGCTCGCGGGAAAT
GGTCGGACGCGTGCTGAAGAGCCTGGAGGAGCAGGGCCTGGTGCATGTGAAAGGAAAGACCATGGTGGTCTTCGGCACCC
GCTGA

Domains

Predicted by InterProScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (22-114)

• Crp-like helix-turn-helix domain (HTH_Crp_2) (146-209)

3D structure

• AlphaFold DB: A0A0H2ZLY6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	67.327	94.393	0.636
crp	Haemophilus influenzae Rd KW20	60.396	94.393	0.57
crp	Acinetobacter baumannii D1279779	54.545	92.523	0.505