Detailed information NTG0324397

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EFV54_RS11495
• Genome accession: NZ_CP033607
• Coordinates: 2237572..2238600 (-)
• Length: 342 a.a.
• NCBI ID: WP_010906347.1
• Uniprot ID: A0AAP4JQE3
• Organism: Lactococcus lactis strain IL1403
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2232572..2243600

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EFV54_RS11470 (EFV54_11470)	-	2232858..2233355 (-)	498	WP_021214977.1	nitroreductase family protein	-
EFV54_RS11475 (EFV54_11475)	-	2233342..2233551 (-)	210	WP_003132661.1	hypothetical protein	-
EFV54_RS11480 (EFV54_11480)	-	2233548..2234375 (-)	828	WP_010906344.1	radical SAM protein	-
EFV54_RS11485 (EFV54_11485)	-	2234368..2236491 (-)	2124	WP_010906345.1	radical SAM protein	-
EFV54_RS11490 (EFV54_11490)	-	2236594..2237451 (-)	858	WP_010906346.1	transcriptional regulator	-
EFV54_RS11495 (EFV54_11495)	sepM	2237572..2238600 (-)	1029	WP_010906347.1	SepM family pheromone-processing serine protease	Regulator
EFV54_RS11500 (EFV54_11500)	coaD	2238587..2239084 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
EFV54_RS11505 (EFV54_11505)	rsmD	2239132..2239671 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EFV54_RS11510 (EFV54_11510)	-	2239842..2241062 (-)	1221	WP_003132654.1	MFS transporter	-
EFV54_RS11515 (EFV54_11515)	lmrP	2241146..2242372 (-)	1227	WP_010906350.1	multidrug efflux MFS transporter LmrP	-
EFV54_RS11520 (EFV54_11520)	-	2242560..2243054 (+)	495	WP_010906351.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37379.98 Da
• Isoelectric Point: 9.9183

>NTDB_id=324397 EFV54_RS11495 WP_010906347.1 2237572..2238600(-) (sepM) [Lactococcus lactis strain IL1403]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKTAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=324397 EFV54_RS11495 WP_010906347.1 2237572..2238600(-) (sepM) [Lactococcus lactis strain IL1403]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGCAGCAACAATTACCTTGGAGCCAAAACCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491