Detailed information NTG0324347

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EFD52_RS10205
• Genome accession: NZ_CP033606
• Coordinates: 2080118..2081146 (-)
• Length: 342 a.a.
• NCBI ID: WP_010906347.1
• Uniprot ID: A0AAP4JQE3
• Organism: Lactococcus lactis strain IL6288
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2075118..2086146

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EFD52_RS10180 (EFD52_10180)	-	2075404..2075901 (-)	498	WP_021214977.1	nitroreductase family protein	-
EFD52_RS10185 (EFD52_10185)	-	2075888..2076097 (-)	210	WP_003132661.1	hypothetical protein	-
EFD52_RS10190 (EFD52_10190)	-	2076094..2076921 (-)	828	WP_010906344.1	radical SAM protein	-
EFD52_RS10195 (EFD52_10195)	-	2076914..2079037 (-)	2124	WP_010906345.1	radical SAM protein	-
EFD52_RS10200 (EFD52_10200)	-	2079140..2079997 (-)	858	WP_010906346.1	transcriptional regulator	-
EFD52_RS10205 (EFD52_10205)	sepM	2080118..2081146 (-)	1029	WP_010906347.1	SepM family pheromone-processing serine protease	Regulator
EFD52_RS10210 (EFD52_10210)	coaD	2081133..2081630 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
EFD52_RS10215 (EFD52_10215)	rsmD	2081678..2082217 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EFD52_RS10220 (EFD52_10220)	-	2082388..2083608 (-)	1221	WP_003132654.1	MFS transporter	-
EFD52_RS10225 (EFD52_10225)	lmrP	2083692..2084918 (-)	1227	WP_010906350.1	multidrug efflux MFS transporter LmrP	-
EFD52_RS10230 (EFD52_10230)	-	2085106..2085600 (+)	495	WP_010906351.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37379.98 Da
• Isoelectric Point: 9.9183

>NTDB_id=324347 EFD52_RS10205 WP_010906347.1 2080118..2081146(-) (sepM) [Lactococcus lactis strain IL6288]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKTAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=324347 EFD52_RS10205 WP_010906347.1 2080118..2081146(-) (sepM) [Lactococcus lactis strain IL6288]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGCAGCAACAATTACCTTGGAGCCAAAACCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491