Detailed information NTG0032417

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: SMUNN2025_RS05250
• Genome accession: NC_013928
• Coordinates: 1054547..1055218 (-)
• Length: 223 a.a.
• NCBI ID: WP_002263237.1
• Uniprot ID: Q8DUD1
• Organism: Streptococcus mutans NN2025
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1049547..1060218

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNN2025_RS05230 (SmuNN2025_1010)	-	1050633..1051322 (+)	690	WP_002269136.1	GntR family transcriptional regulator	-
SMUNN2025_RS05235 (SmuNN2025_1011)	citG	1051328..1052218 (+)	891	WP_002265082.1	triphosphoribosyl-dephospho-CoA synthase CitG	-
SMUNN2025_RS05240 (SmuNN2025_1012)	citC	1052394..1053443 (+)	1050	WP_002278015.1	[citrate (pro-3S)-lyase] ligase	-
SMUNN2025_RS05245 (SmuNN2025_1013)	-	1053597..1054550 (-)	954	WP_002263236.1	sensor histidine kinase	-
SMUNN2025_RS05250 (SmuNN2025_1014)	braR	1054547..1055218 (-)	672	WP_002263237.1	DNA-binding response regulator	Regulator
SMUNN2025_RS05255 (SmuNN2025_1015)	-	1055260..1057263 (-)	2004	WP_002263238.1	ABC transporter permease	-
SMUNN2025_RS05260 (SmuNN2025_1016)	-	1057265..1058017 (-)	753	WP_002265085.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25802.90 Da
• Isoelectric Point: 5.1691

>NTDB_id=32417 SMUNN2025_RS05250 WP_002263237.1 1054547..1055218(-) (braR) [Streptococcus mutans NN2025]
MLKQEKIYLVEDDTTIVNLLKNHLGQHYQVKSVDNFRAILQEVKEFKPDLILMDITLPYFNGFYWTTEIRKSMTMPIIFI
SSADEEMNAVMAMNMGGDDFLSKPFSLPILDAKIAAFLRRANEFTKQGHQIEEFELTLDGVFSNLERQETIQLTPTETKI
LSLLIDYKGEVVTKEALLNRLWEGEEFIDQNTLSVNMTRLRKKVLSVSFDKIHTVRGVGYLIK

Nucleotide

• Length: 672 bp

>NTDB_id=32417 SMUNN2025_RS05250 WP_002263237.1 1054547..1055218(-) (braR) [Streptococcus mutans NN2025]
ATGCTAAAGCAAGAAAAAATTTACTTGGTTGAAGATGATACAACCATTGTCAATCTTTTAAAGAATCATTTGGGACAACA
CTATCAAGTTAAAAGCGTTGATAACTTTAGGGCTATCTTGCAAGAAGTTAAAGAATTTAAACCCGATTTAATTCTGATGG
ATATTACTTTGCCCTATTTCAATGGCTTTTATTGGACTACTGAAATCAGAAAGAGCATGACCATGCCCATTATTTTTATT
TCCAGTGCTGATGAAGAAATGAATGCAGTAATGGCTATGAATATGGGAGGTGATGATTTTTTGAGCAAGCCTTTCTCGCT
GCCTATTTTGGATGCCAAAATCGCTGCTTTCTTGCGCCGTGCTAACGAGTTCACTAAGCAAGGCCATCAAATTGAAGAGT
TTGAATTAACGTTAGATGGTGTATTCTCAAATTTAGAAAGACAAGAGACTATCCAATTGACTCCAACAGAAACGAAAATT
CTTTCCTTACTTATTGATTATAAAGGAGAGGTTGTCACTAAGGAAGCTCTTCTCAATCGACTATGGGAGGGAGAGGAATT
TATTGATCAAAACACGCTTAGTGTCAATATGACACGTCTTCGTAAAAAGGTTCTATCAGTAAGTTTTGATAAGATTCATA
CAGTAAGAGGAGTAGGGTATTTAATTAAATGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (7-114)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (149-221)

3D structure

• AlphaFold DB: Q8DUD1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	43.498	100	0.435