Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   SMUNN2025_RS01645 Genome accession   NC_013928
Coordinates   337486..338271 (+) Length   261 a.a.
NCBI ID   WP_002263472.1    Uniprot ID   P59388
Organism   Streptococcus mutans NN2025     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 332486..343271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS01625 (SmuNN2025_0306) - 333240..334625 (+) 1386 WP_002268948.1 Cof-type HAD-IIB family hydrolase -
  SMUNN2025_RS01630 (SmuNN2025_0307) - 334903..335352 (-) 450 WP_002263469.1 universal stress protein -
  SMUNN2025_RS01635 (SmuNN2025_0308) - 335450..335986 (-) 537 WP_002277428.1 biotin transporter BioY -
  SMUNN2025_RS01640 (SmuNN2025_0309) - 336163..337377 (+) 1215 WP_002277427.1 pyridoxal phosphate-dependent aminotransferase -
  SMUNN2025_RS01645 (SmuNN2025_0310) codY 337486..338271 (+) 786 WP_002263472.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  SMUNN2025_RS01650 (SmuNN2025_0311) - 338273..338824 (+) 552 WP_002263473.1 cysteine hydrolase family protein -
  SMUNN2025_RS01655 (SmuNN2025_0312) aspS 339082..340833 (+) 1752 WP_002277426.1 aspartate--tRNA ligase -
  SMUNN2025_RS01660 (SmuNN2025_0313) gatC 340961..341263 (+) 303 WP_002263475.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  SMUNN2025_RS01665 (SmuNN2025_0314) gatA 341263..342729 (+) 1467 WP_002271770.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 28970.13 Da        Isoelectric Point: 4.5032

>NTDB_id=32388 SMUNN2025_RS01645 WP_002263472.1 337486..338271(+) (codY) [Streptococcus mutans NN2025]
MANLLSKTRRITSILQRSVESLQSDLPYNTIADQLAEIIDCNACIIDGSGIILGYAMKYKTNTDRVEEFFQAKKLPDDYV
KSASRIYDTEANLSVENDLTIFPIESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDKEFNDDDLILIEISSTVVGIQLLN
LQTENLEETIRKQTAINMAINTLSYSEMKAVAAILNELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKDYS

Nucleotide


Download         Length: 786 bp        

>NTDB_id=32388 SMUNN2025_RS01645 WP_002263472.1 337486..338271(+) (codY) [Streptococcus mutans NN2025]
ATGGCTAATTTATTATCGAAAACGCGACGTATTACATCCATTTTACAACGCTCGGTTGAGAGCCTTCAAAGTGATTTGCC
TTATAATACGATTGCAGATCAATTGGCTGAAATTATTGATTGTAATGCTTGTATTATTGATGGTAGTGGTATTATTCTCG
GCTATGCTATGAAGTATAAAACCAATACAGATCGTGTTGAAGAATTTTTCCAAGCTAAAAAATTACCTGATGATTATGTA
AAATCAGCCAGCCGTATTTATGATACAGAAGCCAATCTGTCGGTTGAAAATGATTTGACCATTTTTCCAATTGAATCAAA
AGATATCTATCCTGATGGCTTGACGACTATTGCTCCCATCTATGGCGGCGGTATGCGTCTTGGTTCTCTTATTATCTGGC
GTAATGATAAAGAATTCAATGATGACGATTTGATTCTAATTGAGATTTCTTCTACTGTTGTTGGAATTCAATTATTGAAC
TTGCAGACAGAAAATCTTGAAGAAACAATTCGTAAGCAGACTGCTATTAATATGGCGATTAATACCTTGTCTTATTCAGA
AATGAAAGCTGTCGCAGCTATTCTCAATGAATTAGATGGCAATGAAGGTCGCTTGACCGCATCGGTTATTGCTGATCGTA
TCGGTATTACACGTAGCGTGATTGTTAATGCTCTTAGAAAGTTAGAAAGTGCCGGTATTATTGAAAGTCGTTCCTTAGGT
ATGAAAGGTACTTATCTCAAAGTTATTAATGAAGGTATTTTTGATAAATTAAAGGACTATAGTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59388

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.37

98.467

0.644
  codY Bacillus subtilis subsp. subtilis str. 168

48.047

98.084

0.471

Multiple sequence alignment