Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   FHI56_RS04050 Genome accession   NZ_CP040804
Coordinates   578122..580227 (+) Length   701 a.a.
NCBI ID   WP_049529235.1    Uniprot ID   -
Organism   Streptococcus salivarius strain LAB813     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 573122..585227
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FHI56_RS04020 (FHI56_04020) yqeK 573495..574085 (+) 591 WP_049529230.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  FHI56_RS04025 (FHI56_04025) rsfS 574109..574462 (+) 354 WP_014632696.1 ribosome silencing factor -
  FHI56_RS04030 (FHI56_04030) - 574906..575646 (+) 741 WP_013991077.1 class I SAM-dependent methyltransferase -
  FHI56_RS04035 (FHI56_04035) - 575652..576743 (+) 1092 WP_070579632.1 nucleotidyltransferase -
  FHI56_RS04040 (FHI56_04040) - 576885..577139 (+) 255 WP_060971904.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  FHI56_RS04045 (FHI56_04045) - 577143..577397 (+) 255 WP_070579630.1 Txe/YoeB family addiction module toxin -
  FHI56_RS04050 (FHI56_04050) clpE 578122..580227 (+) 2106 WP_049529235.1 AAA family ATPase Regulator
  FHI56_RS11860 - 580663..580788 (+) 126 WP_002884447.1 hypothetical protein -
  FHI56_RS04055 (FHI56_04055) - 580806..581414 (+) 609 WP_002884297.1 DUF4230 domain-containing protein -
  FHI56_RS11645 - 581989..582156 (+) 168 WP_014634940.1 hypothetical protein -
  FHI56_RS04065 (FHI56_04065) - 582337..582636 (-) 300 WP_014634939.1 hypothetical protein -
  FHI56_RS04070 (FHI56_04070) - 582633..583052 (-) 420 WP_037599159.1 HIT family protein -
  FHI56_RS04075 (FHI56_04075) pptA 583117..583848 (+) 732 WP_149561190.1 ABC transporter ATP-binding protein Regulator
  FHI56_RS04080 (FHI56_04080) pptB 583848..584882 (+) 1035 WP_392396793.1 ABC transporter permease Regulator

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77405.33 Da        Isoelectric Point: 4.7499

>NTDB_id=323554 FHI56_RS04050 WP_049529235.1 578122..580227(+) (clpE) [Streptococcus salivarius strain LAB813]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQHQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTEDLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=323554 FHI56_RS04050 WP_049529235.1 578122..580227(+) (clpE) [Streptococcus salivarius strain LAB813]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATCTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACATCAAGGTAAAGGACCTAAACAAGATGGCATCCTTGCTAAACTTGGTCGAAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCAGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACTAAGAATAACCCAGTCCTTGTCGGGGACGCTGGGGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCTC
AAGCCATCGTAAATGGTGATGTCCCAGCTGCTATCAAGAACAAAGAAATCATCTCAATTGATATTTCTGGACTTGAAGCT
GGTACGCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAATATCATTCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGTGATGGTCAAGGATCTAAAGGTCTTGCTGATATCT
TGAAACCTGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAGGATGAATACCGTAACACTATCTTGAAG
AACGCAGCTCTTGCTCGTCGTTTCAACGAAGTTAAGGTTAATGCTCCTTCTGCAGAAGATACTTTCAAGATTCTCCAAGG
TATTCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCGGATGAAGTCTTGAAAGCAGCAGTAGATTTCTCTGTGC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTGACAGCGGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAAGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCATACAGAAGACCTTAAAG
TCACAGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTGTCACAAATGGGTGCAACTGAT
ATCGAACGTTTGAAAGATATGGGTCACCGTTTGCAAACTAAGGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATTGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGAACTAAAGATGCTATCATCCGTTTGGATATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTTATCA
CACTTCTTCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGATTTGGCTATGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACTCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGCCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)

AAA lid domain (AAA_lid_9)

(257-351)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.857

99.857

0.468
  clpC Lactococcus lactis subsp. cremoris KW2

49.54

93.01

0.461
  clpE Streptococcus pneumoniae D39

48.678

91.726

0.447
  clpE Streptococcus pneumoniae R6

48.678

91.726

0.447
  clpE Streptococcus pneumoniae Rx1

48.678

91.726

0.447
  clpE Streptococcus pneumoniae TIGR4

48.442

91.583

0.444
  clpC Bacillus subtilis subsp. subtilis str. 168

45.538

92.725

0.422
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.243

92.867

0.392
  clpC Streptococcus pneumoniae TIGR4

43.248

88.73

0.384
  clpC Streptococcus pneumoniae Rx1

43.248

88.73

0.384
  clpC Streptococcus pneumoniae D39

43.248

88.73

0.384
  clpC Streptococcus thermophilus LMD-9

42.95

88.017

0.378
  clpC Streptococcus thermophilus LMG 18311

42.811

88.302

0.378
  clpC Streptococcus mutans UA159

42.332

89.301

0.378