Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FHI56_RS01550 Genome accession   NZ_CP040804
Coordinates   107011..108948 (-) Length   645 a.a.
NCBI ID   WP_118058338.1    Uniprot ID   -
Organism   Streptococcus salivarius strain LAB813     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 102011..113948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FHI56_RS01520 (FHI56_01520) spx 102243..102641 (-) 399 WP_002886328.1 transcriptional regulator Spx -
  FHI56_RS01525 (FHI56_01525) recA 102808..103947 (-) 1140 WP_002886327.1 recombinase RecA Machinery gene
  FHI56_RS01530 (FHI56_01530) cinA 103983..105251 (-) 1269 WP_002886326.1 competence/damage-inducible protein A Machinery gene
  FHI56_RS01535 (FHI56_01535) - 105348..105902 (-) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  FHI56_RS01540 (FHI56_01540) ruvA 105911..106501 (-) 591 WP_002886323.1 Holliday junction branch migration protein RuvA Machinery gene
  FHI56_RS01545 (FHI56_01545) - 106659..106880 (-) 222 WP_002886321.1 hypothetical protein -
  FHI56_RS01550 (FHI56_01550) hexB 107011..108948 (-) 1938 WP_118058338.1 DNA mismatch repair endonuclease MutL Machinery gene
  FHI56_RS01555 (FHI56_01555) - 108998..109303 (-) 306 WP_064524956.1 hypothetical protein -
  FHI56_RS01560 (FHI56_01560) - 109482..109919 (+) 438 WP_002886318.1 LytTR family DNA-binding domain-containing protein -
  FHI56_RS01565 (FHI56_01565) - 109916..110371 (+) 456 WP_084871097.1 DUF3021 domain-containing protein -
  FHI56_RS01570 (FHI56_01570) hexA 110405..112963 (-) 2559 WP_149561121.1 DNA mismatch repair protein MutS Machinery gene
  FHI56_RS01575 (FHI56_01575) - 112956..113315 (-) 360 WP_045772359.1 YlbF family regulator -
  FHI56_RS01580 (FHI56_01580) argR 113315..113743 (-) 429 WP_170314548.1 arginine repressor -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72243.31 Da        Isoelectric Point: 5.2797

>NTDB_id=323520 FHI56_RS01550 WP_118058338.1 107011..108948(-) (hexB) [Streptococcus salivarius strain LAB813]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGAAKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLVSESPVSSVENKPQP
SVKQAQRSVDEGDGEHEKLDYKNKSKMKRMLETLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKYEY
YREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMSLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDMLLL
TNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTSLR
DLGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=323520 FHI56_RS01550 WP_118058338.1 107011..108948(-) (hexB) [Streptococcus salivarius strain LAB813]
ATGCCAAAAATCATCGAATTACCTGAGGTGTTAGCCAACCAGATTGCTGCTGGTGAGGTCGTAGAGCGCCCAGCCAGTGT
TGTCAAAGAGTTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACCATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGACAATGGTGAAGGAATGGCTCAAGCTGATGTGGCCATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACCCTTGGTTTTCGAGGTGAGGCCCTACCATCAATAGCTTCTATCAG
CCACCTAACTATTGTGACAGCAGCGGATGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGGTGGAGAAATTGAGAGTC
AGGACCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACCTATTTTATAATACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTAAGTCTAGCTCATCCCGAGGTTGCCTT
TACCTTGCTTAATGATGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTCCGTCAAGCTATTGCTGGTATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAGATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGATATGTTAGTCTCCCT
GAGTTGACCCGTGCAAATCGTAACTACATCACGATTCTCATTAACGGACGTTATATTAAAAACTTCCTGCTTAACCGTGC
TATTTTTGATGGATATGGCTCTAAACTCATGGTAGGACGCTTCCCTATTGCAGTTATTGATATTCAGATTGATCCTTACT
TGGCCGATGTCAATGTTCACCCAACAAAGCAGGAAGTACGTATCTCTAAAGAAAAAGAGCTCATGGCCCTTATCAGCTCA
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACCAGAGGTGC
AGCTAAGCCAGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTACGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAAGATATCAAACCTCTTGTATCAGAGTCACCAGTTTCATCGGTAGAAAATAAACCGCAACCT
TCTGTTAAACAGGCACAACGTTCAGTAGATGAAGGTGATGGCGAACACGAAAAACTTGATTATAAAAACAAGTCGAAAAT
GAAGCGCATGCTTGAAACTCTGGACAATGAGGAAACATCAACCTTCCCTGAATTAGAGTTTTTTGGTCAAATGCATGGAA
CCTATCTCTTTGCGCAAGGACAAGGCGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTATGAGTAC
TACCGCGAAAAGATTGGTGAGGTTGACAGCAGTTTACAGCAGCTTTTGGTTCCCTATCTCTTTGAATTTTCAGGTTCAGA
CTACATTAGTTTACAAGAAAAAATGTCCCTTCTTAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAACAACACTTTCA
TTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCAGCGGTCTATGAAATGTGTGACATGCTTCTTTTG
ACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTGGCCATCATGATGAGTTGTAAACGTTCAATCAAGGCCAATCA
TGCTCTTGATGATTACTCTGCGCGTGACCTCCTAGTACAGCTTGCACAGTGTAAAAATCCCTACAATTGCCCTCACGGAC
GTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGTATCCAAGAAAATCATACGAGTCTACGT
GACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(446-589)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.665

100

0.709