Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   EB816_RS09645 Genome accession   NZ_CP033337
Coordinates   1886098..1886811 (+) Length   237 a.a.
NCBI ID   WP_002982243.1    Uniprot ID   A0A9X5LXW4
Organism   Streptococcus pyogenes strain TSPY453     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1881098..1891811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EB816_RS09635 (EB816_09640) treC 1882168..1883796 (-) 1629 WP_023612559.1 alpha,alpha-phosphotrehalase -
  EB816_RS09640 (EB816_09645) treP 1883863..1885887 (-) 2025 WP_023612582.1 PTS system trehalose-specific EIIBC component -
  EB816_RS09645 (EB816_09650) treR 1886098..1886811 (+) 714 WP_002982243.1 trehalose operon repressor Regulator
  EB816_RS09655 (EB816_09660) - 1887091..1887357 (-) 267 WP_076637095.1 winged helix-turn-helix transcriptional regulator -
  EB816_RS09660 (EB816_09665) - 1887615..1888472 (+) 858 WP_032465608.1 VOC family protein -
  EB816_RS09665 (EB816_09670) yaaA 1888514..1889245 (+) 732 WP_023612602.1 peroxide stress protein YaaA -
  EB816_RS09670 (EB816_09675) nrdG 1889419..1890033 (-) 615 WP_021775544.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  EB816_RS09675 (EB816_09680) - 1890048..1890542 (-) 495 WP_011055085.1 GNAT family N-acetyltransferase -
  EB816_RS09680 (EB816_09685) - 1890551..1891486 (-) 936 WP_010922750.1 Gfo/Idh/MocA family oxidoreductase -
  EB816_RS10230 - 1891515..1891661 (-) 147 WP_011106921.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27592.78 Da        Isoelectric Point: 9.6226

>NTDB_id=323152 EB816_RS09645 WP_002982243.1 1886098..1886811(+) (treR) [Streptococcus pyogenes strain TSPY453]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=323152 EB816_RS09645 WP_002982243.1 1886098..1886811(+) (treR) [Streptococcus pyogenes strain TSPY453]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAAACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACGCGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.803

98.734

0.679

Multiple sequence alignment