Detailed information NTG0323088

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EB817_RS07070
• Genome accession: NZ_CP033336
• Coordinates: 1381108..1382109 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain TSPY165
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1376108..1387109

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EB817_RS07055 (EB817_07065)	thrS	1376278..1378221 (-)	1944	WP_129304872.1	threonine--tRNA ligase	-
EB817_RS07060 (EB817_07070)	-	1378643..1379977 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
EB817_RS07065 (EB817_07075)	-	1379979..1380977 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
EB817_RS07070 (EB817_07080)	ccpA	1381108..1382109 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
EB817_RS07075 (EB817_07085)	-	1382283..1383368 (+)	1086	WP_129304873.1	Xaa-Pro peptidase family protein	-
EB817_RS07080 (EB817_07090)	-	1383417..1384082 (+)	666	WP_129304874.1	NAD(P)H-dependent oxidoreductase	-
EB817_RS07085 (EB817_07095)	-	1384093..1384470 (+)	378	WP_002985686.1	VOC family protein	-
EB817_RS07090 (EB817_07100)	-	1384615..1385541 (+)	927	WP_011106859.1	glycosyltransferase family 2 protein	-
EB817_RS07095 (EB817_07105)	-	1385752..1386435 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=323088 EB817_RS07070 WP_002985680.1 1381108..1382109(-) (ccpA) [Streptococcus pyogenes strain TSPY165]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=323088 EB817_RS07070 WP_002985680.1 1381108..1382109(-) (ccpA) [Streptococcus pyogenes strain TSPY165]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGTAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTTAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559