Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   EB818_RS08690 Genome accession   NZ_CP033335
Coordinates   1718518..1719231 (+) Length   237 a.a.
NCBI ID   WP_002992823.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY208     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1713518..1724231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EB818_RS08680 (EB818_08695) treC 1714587..1716215 (-) 1629 WP_111674754.1 alpha,alpha-phosphotrehalase -
  EB818_RS08685 (EB818_08700) treP 1716283..1718307 (-) 2025 WP_111674755.1 PTS system trehalose-specific EIIBC component -
  EB818_RS08690 (EB818_08705) treR 1718518..1719231 (+) 714 WP_002992823.1 trehalose operon repressor Regulator
  EB818_RS08700 (EB818_08715) - 1719511..1719777 (-) 267 WP_076637095.1 winged helix-turn-helix transcriptional regulator -
  EB818_RS08705 (EB818_08720) - 1720035..1720892 (+) 858 WP_023605347.1 VOC family protein -
  EB818_RS08710 (EB818_08725) yaaA 1720934..1721665 (+) 732 WP_002982222.1 peroxide stress protein YaaA -
  EB818_RS08715 (EB818_08730) nrdG 1721839..1722453 (-) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  EB818_RS08720 (EB818_08735) - 1722453..1722962 (-) 510 WP_002991345.1 GNAT family N-acetyltransferase -
  EB818_RS08725 (EB818_08740) - 1722971..1723906 (-) 936 WP_076639525.1 Gfo/Idh/MocA family oxidoreductase -
  EB818_RS09190 - 1723935..1724081 (-) 147 WP_002982210.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27620.79 Da        Isoelectric Point: 9.6307

>NTDB_id=323041 EB818_RS08690 WP_002992823.1 1718518..1719231(+) (treR) [Streptococcus pyogenes strain TSPY208]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=323041 EB818_RS08690 WP_002992823.1 1718518..1719231(+) (treR) [Streptococcus pyogenes strain TSPY208]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAGACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACGCGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.376

98.734

0.675

Multiple sequence alignment