Detailed information NTG0032237

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: GALLO_RS11265
• Genome accession: NC_013798
• Coordinates: 2284425..2286995 (-)
• Length: 856 a.a.
• NCBI ID: WP_009855174.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus UCN34
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2279425..2291995

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GALLO_RS12030	-	2279515..2279688 (-)	174	WP_009855168.1	hypothetical protein	-
GALLO_RS11240 (GALLO_2194)	-	2279738..2280202 (-)	465	WP_009855169.1	hypothetical protein	-
GALLO_RS11245 (GALLO_2195)	-	2280272..2280679 (-)	408	WP_009855170.1	hypothetical protein	-
GALLO_RS11250 (GALLO_2196)	-	2280842..2281696 (+)	855	WP_009855171.1	helix-turn-helix domain-containing protein	-
GALLO_RS11255 (GALLO_2197)	ruvA	2281770..2282363 (-)	594	WP_009855172.1	Holliday junction branch migration protein RuvA	Machinery gene
GALLO_RS11260 (GALLO_2198)	hexB	2282365..2284308 (-)	1944	WP_012962624.1	DNA mismatch repair endonuclease MutL	Machinery gene
GALLO_RS11265 (GALLO_2199)	hexA	2284425..2286995 (-)	2571	WP_009855174.1	DNA mismatch repair protein MutS	Machinery gene
GALLO_RS11270 (GALLO_2200)	-	2286982..2287338 (-)	357	WP_009855175.1	YlbF family regulator	-
GALLO_RS11275 (GALLO_2201)	argR	2287335..2287772 (-)	438	WP_003066930.1	arginine repressor	-
GALLO_RS11280 (GALLO_2202)	argS	2287963..2289654 (+)	1692	WP_009855176.1	arginine--tRNA ligase	-
GALLO_RS11285 (GALLO_2203)	-	2289767..2290060 (+)	294	WP_009855177.1	bacteriocin immunity protein	-
GALLO_RS11290 (GALLO_2204)	-	2290101..2291606 (-)	1506	WP_012962625.1	prolyl oligopeptidase family serine peptidase	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 95896.23 Da
• Isoelectric Point: 4.8516

>NTDB_id=32237 GALLO_RS11265 WP_009855174.1 2284425..2286995(-) (hexA) [Streptococcus gallolyticus UCN34]
MTKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTAVDSSKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFFSTSLSDFTS
LRSEILNLKAREVVVGYELSETEQHSLVKQLNLLLSFEQERYEDVHLIDPDLTALEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQAQIEERQNIVQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLAQVPTIKAILESFESPHLDKLVNNIDTLPELESLIRSAIAP
DAPAVITEGSIIRTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAREQSASLEYDIFMRVRGQVERYITRLQDLAKAISTVDVLQSLAVVAENNHYVRPTFN
DSHEIKIEKGRHAVVEKVMGTQEYIPNTITFDADINIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVNLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASSQSLILFDELGRGTATYDGMALAQSIIEYIHNHIGAKTMFATHYHEL
TALSTSLTHLINVHVATLEKNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEELLQRADSILTNLESGAAQLQLTPEVEVG
PITVKSEVAEPVAEQLSLFADDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2571 bp

>NTDB_id=32237 GALLO_RS11265 WP_009855174.1 2284425..2286995(-) (hexA) [Streptococcus gallolyticus UCN34]
ATGACAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGACGTAAAAAAAGATTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGACTTTTATGAATTATTTTATGATGATGCGGTTAAAGCTGCACAGATTTTAGAGATTAGTTTAACTAGTC
GTAATAAAAATGCTGACAATCCAATTCCAATGGCAGGTGTGCCTTATCATTCTGCGCAACAATACATTGATGTATTAGTG
GAAATGGGTTACAAGGTGGCAATTGCTGAGCAAATGGAAGACCCAAAACAAGCCGTCGGTGTGGTTAAACGTGAAGTCGT
TCAAGTGATTACGCCAGGAACAGCTGTCGATTCCTCTAAACCAGATAATGCTAACAATTTCTTGGTGGCTATCGATTCTG
ACGGCAAAACGTTTGGGCTAGCCTATATGGACGTGTCAACAGGTGAATTTTTCTCAACAAGTCTTTCTGATTTTACAAGC
CTTAGAAGTGAAATTCTGAACCTTAAAGCGCGTGAAGTTGTTGTTGGTTATGAGCTTTCTGAAACAGAGCAACATAGCTT
AGTCAAACAATTAAATTTACTCTTATCGTTTGAACAAGAACGTTATGAAGATGTGCATTTAATCGACCCAGATTTAACGG
CTTTAGAAATTTCAGCAGCTGAGAAATTGCTACAATACGTTCATACAACGCAAAAACGTGAGCTAAGCCATTTGCAAAAA
TTGGTTCATTATGAAATCAAAGATTACTTGCAAATGTCTTATACGACAAAATCTAGTCTGGATTTATTAGAAAATGCTCG
AACAAGTAAAAAACATGGTAGCCTTTATTGGTTACTAGATGAAACTAAAACGGCTATGGGAATGCGTCTATTGCGCAATT
GGATTGACCGTCCTTTGGTGAACCAAGCACAGATTGAAGAGCGCCAAAATATTGTTCAAGTTTTCCTAGATAATTTCTTT
GAGCGTAGTGATTTGACGGATAGTCTCAAAGGTGTTTATGATATTGAACGTTTAGCGAGTCGTGTGTCATTTGGAAAAGC
TAATCCAAAAGATTTATTACAACTCGGTCATACTTTGGCACAAGTGCCAACGATTAAGGCGATTTTAGAATCGTTTGAGA
GCCCTCACCTTGACAAGCTTGTCAACAACATTGACACTTTGCCAGAGCTAGAATCGCTGATTCGCTCAGCTATTGCCCCA
GATGCCCCTGCTGTTATCACAGAAGGTAGCATTATCCGTACAGGCTTTGATGAGACTTTGGATAAATACCGTAAGGTTAT
GCGCGAGGGGACTAGCTGGATTGCAGAAATTGAAGCTAAGGAACGTGCTGCAAGTGGGATTACCAATCTAAAAATTGATT
ATAATAAAAAAGACGGATACTATTTCCATGTGACAAATTCCAATCTCTCTCTAGTGCCAGATTATTTCTTCCGCAAGGCA
ACGTTGAAAAATTCAGAGCGTTTCGGAACGGCAGAATTGGCAAAAATTGAAGGTGAGATGTTGGAGGCGCGTGAGCAATC
AGCAAGCTTAGAATATGATATTTTCATGCGCGTTCGCGGACAAGTTGAGCGTTACATTACACGTTTGCAAGACTTGGCTA
AGGCGATTTCAACCGTTGACGTTTTACAAAGTTTAGCCGTTGTTGCAGAAAATAATCATTATGTTCGTCCGACGTTCAAC
GATAGCCATGAAATTAAGATTGAAAAAGGTCGTCATGCGGTCGTTGAAAAAGTCATGGGAACGCAAGAATATATTCCTAA
TACGATTACGTTTGATGCCGATATCAACATTCAACTGATTACTGGTCCAAATATGAGTGGTAAATCAACTTATATGCGTC
AACTTGCCTTGACAGTTATTATGGCTCAAATGGGGTCTTACGTAGCTGCTGAAAGTGTCAATTTACCAGTATTTGATGCG
ATTTTCACGCGTATTGGTGCGGCAGATGATTTGATTTCAGGACAGTCAACGTTTATGGTGGAAATGATGGAAGCTAACCA
AGCTATCAAACGTGCAAGTTCTCAATCCTTGATTCTTTTTGATGAGCTAGGTCGTGGTACAGCAACCTATGACGGTATGG
CTTTGGCGCAATCAATCATTGAATATATCCATAATCATATCGGTGCAAAGACCATGTTTGCAACCCATTATCATGAGTTG
ACAGCTTTGTCAACAAGCTTGACGCACCTTATCAATGTTCACGTTGCGACTCTTGAGAAAAATGGTGATGTGACTTTTCT
TCATAAAATTGCAGAAGGTCCAGCAGACAAATCTTACGGAATTCATGTAGCAAAAATTGCTGGTTTACCAGAAGAATTAT
TACAACGTGCGGACAGCATTTTGACGAATTTAGAATCAGGTGCTGCGCAGCTTCAATTGACCCCTGAGGTAGAAGTTGGG
CCAATTACTGTAAAATCTGAAGTAGCAGAACCAGTGGCAGAGCAACTAAGTTTATTTGCTGATGACTCATCTAACCAAGA
AGTGATTGAAGCACTCAAAAAAGTTGATTTGATGAATTTAACACCAATGCAAGCCATGAATGTTATTTATGAATTAAAAA
ATATGTTGTAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.43	100	0.724
mutS	Pseudomonas stutzeri strain ATCC 17587	37.716	100	0.382