Detailed information NTG0321325

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EAH52_RS04655
• Genome accession: NZ_CP033098
• Coordinates: 955346..956389 (+)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain SWO
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 950346..961389

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EAH52_RS04630	-	951402..952127 (+)	726	WP_002466154.1	type 1 glutamine amidotransferase	-
EAH52_RS04635	-	952195..953181 (-)	987	WP_031464159.1	aromatic acid exporter family protein	-
EAH52_RS04640	map	953348..954103 (+)	756	WP_002466104.1	type I methionyl aminopeptidase	-
EAH52_RS04645	-	954247..954633 (+)	387	WP_002466133.1	DUF2543 family protein	-
EAH52_RS04650	liaF	954648..955349 (+)	702	WP_002466140.1	cell wall-active antibiotics response protein LiaF	-
EAH52_RS04655	vraS	955346..956389 (+)	1044	WP_002466111.1	sensor histidine kinase	Regulator
EAH52_RS04660	vraR	956379..957008 (+)	630	WP_002466112.1	two-component system response regulator VraR	Regulator
EAH52_RS04665	-	957067..958302 (-)	1236	WP_002466159.1	YihY/virulence factor BrkB family protein	-
EAH52_RS04670	-	958520..958804 (-)	285	WP_002466132.1	YtxH domain-containing protein	-
EAH52_RS04675	-	958811..959275 (-)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
EAH52_RS04680	-	959422..959625 (+)	204	WP_002466135.1	DUF1128 domain-containing protein	-
EAH52_RS04685	-	959638..960879 (+)	1242	WP_002466147.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=321325 EAH52_RS04655 WP_002466111.1 955346..956389(+) (vraS) [Staphylococcus warneri strain SWO]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=321325 EAH52_RS04655 WP_002466111.1 955346..956389(+) (vraS) [Staphylococcus warneri strain SWO]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTCCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948