Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   FD987_RS06390 Genome accession   NZ_CP040239
Coordinates   1252290..1254104 (-) Length   604 a.a.
NCBI ID   WP_023362037.1    Uniprot ID   -
Organism   Campylobacter coli strain S9     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1247290..1259104
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD987_RS06365 (FD987_06365) - 1247870..1248475 (-) 606 WP_002777482.1 hypothetical protein -
  FD987_RS06370 (FD987_06370) - 1248718..1249029 (+) 312 WP_002777486.1 hypothetical protein -
  FD987_RS06375 (FD987_06375) hemE 1249177..1250199 (+) 1023 WP_002789869.1 uroporphyrinogen decarboxylase -
  FD987_RS06380 (FD987_06380) - 1250196..1251098 (+) 903 WP_002777490.1 radical SAM protein -
  FD987_RS06385 (FD987_06385) - 1251095..1252288 (-) 1194 WP_002777493.1 hypothetical protein -
  FD987_RS06390 (FD987_06390) uvrC 1252290..1254104 (-) 1815 WP_023362037.1 excinuclease ABC subunit UvrC Machinery gene
  FD987_RS06395 (FD987_06395) - 1254097..1254573 (-) 477 WP_002777499.1 hypothetical protein -
  FD987_RS06400 (FD987_06400) guaA 1254710..1256245 (+) 1536 WP_023362039.1 glutamine-hydrolyzing GMP synthase -
  FD987_RS06405 (FD987_06405) - 1256419..1257027 (+) 609 WP_002777505.1 class I SAM-dependent methyltransferase -
  FD987_RS06410 (FD987_06410) - 1257150..1257707 (-) 558 WP_002787933.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 604 a.a.        Molecular weight: 69736.76 Da        Isoelectric Point: 9.3346

>NTDB_id=320650 FD987_RS06390 WP_023362037.1 1252290..1254104(-) (uvrC) [Campylobacter coli strain S9]
MAEILLKNTLKEELQTLPANAGVYQYFNAEGKLLYVGKAKNLKNRVRSYFAFTPNLRANPKNSLRIQKMIEEAVHLEFIT
TNSEADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFNEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYP
LKQKASCKSPCIFYQISRCLAPCDKKITQEEYRLILDKAINALLSPSILVKNLEKQMFHLAQNENYEEAAKIRDQIATIR
DLEIKVEIDIAKLEDFEIFALACESSMLSTLRFVVQNGKIISANSKITPLKNNTDFDKNEIYKQLILENFSVDIPLVANT
VYVYEDFEDRELLEEILSQRFDKKISIKVPKIGEKRRICDLAFQNACLNIQKEQKNSDFNIQKELKNYFELKNLPNCIEV
FDNSHLQGVANVGAMITYKMGTWDKSNYRKFHLKYKNDYEQMREVLTRRALEFDKMPAPDLWLIDGGKALLDLAKEIILS
SGANVDILAISKEKINAKAHRAKGGAKDKIHSLKGEFALSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLSSSKLVK
SGLSAGVIQKLLAYYGSFEAIYEANFEELCQLVGKKSAQKIKED

Nucleotide


Download         Length: 1815 bp        

>NTDB_id=320650 FD987_RS06390 WP_023362037.1 1252290..1254104(-) (uvrC) [Campylobacter coli strain S9]
ATGGCTGAAATTTTACTTAAAAATACTCTCAAAGAAGAGCTTCAAACCCTACCTGCAAATGCTGGAGTGTATCAGTATTT
TAATGCCGAAGGAAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAACCGCGTAAGATCTTATTTTGCTTTTACCC
CAAATTTACGCGCCAATCCAAAAAATTCTTTAAGAATTCAAAAAATGATAGAAGAAGCGGTGCATTTGGAATTTATTACA
ACAAATTCAGAAGCTGATGCTTTGATTTTGGAAAATTCTTTTATCAAGCAACTTCATCCAAAATACAATATTTTACTAAG
AGATGATAAGACTTATCCTTATATTTATGTAGATTTTAATGAAGAATTTCCGCGTTTTGAAATCACTAGAAAATTAGTTA
AAAAAAGTAAAATCAAATATTTTGGCCCCTTTTTTAAAGGAGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCT
TTAAAGCAAAAAGCAAGTTGTAAATCTCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAAAAAAT
TACCCAAGAAGAATATCGTTTGATTTTAGATAAAGCTATCAATGCTCTTTTAAGCCCTAGTATTTTAGTGAAAAATTTGG
AAAAACAAATGTTTCATTTAGCCCAAAATGAGAATTATGAAGAAGCGGCAAAAATAAGAGATCAGATTGCTACGATAAGG
GATTTGGAAATTAAAGTTGAGATTGATATCGCTAAATTAGAAGACTTTGAAATTTTTGCTTTAGCTTGTGAAAGCTCTAT
GCTTTCAACTTTGCGTTTTGTGGTGCAAAATGGAAAAATCATCAGCGCTAATTCTAAAATCACTCCGCTTAAAAACAATA
CAGATTTTGATAAAAATGAGATTTATAAACAGCTTATTTTAGAAAATTTTAGCGTAGACATTCCTTTGGTTGCAAATACT
GTTTATGTTTATGAGGATTTTGAAGACAGGGAGCTTTTAGAAGAAATTTTAAGCCAGAGATTTGATAAAAAAATCAGCAT
TAAAGTTCCTAAAATAGGGGAAAAAAGAAGAATTTGTGATTTGGCATTTCAAAATGCGTGTTTAAATATACAAAAAGAGC
AAAAAAATAGTGATTTTAATATACAAAAAGAACTTAAAAATTATTTCGAGCTTAAAAATCTGCCAAATTGTATAGAAGTT
TTTGATAATTCTCATTTGCAAGGTGTGGCGAATGTAGGAGCTATGATAACTTATAAAATGGGTACTTGGGATAAGTCAAA
TTATAGAAAATTTCATTTAAAATACAAAAATGATTATGAGCAAATGCGTGAAGTTTTAACGCGTAGAGCATTAGAATTTG
ACAAAATGCCTGCTCCTGATTTGTGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTAGCTAAAGAAATCATCTTAAGT
AGTGGGGCAAATGTTGATATTTTAGCAATCTCAAAAGAAAAAATCAATGCTAAAGCTCACCGCGCTAAAGGAGGGGCTAA
AGATAAAATTCACTCTTTAAAAGGAGAATTTGCCCTAAGCATTAACGATAAAAAATTACAATTCTTACAGAAATTAAGAG
ATGAAGCACATCGTTTTGCCATAAGTTTTCATCAAAACACTAAGAAAAAACAAGATTTATCAAGCTCTAAGCTTGTAAAA
TCAGGACTTAGTGCGGGAGTTATACAAAAACTTTTGGCGTATTATGGAAGTTTTGAAGCTATTTATGAGGCAAATTTTGA
AGAATTGTGCCAATTAGTAGGAAAAAAATCAGCACAAAAAATAAAGGAAGATTGA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(387-541)

GIY-YIG catalytic domain (GIY-YIG)

(21-103)

UvrB/uvrC motif (UVR)

(209-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

45.84

97.517

0.447