Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   D4G81_RS04780 Genome accession   NZ_CP032913
Coordinates   995148..996932 (+) Length   594 a.a.
NCBI ID   WP_139524409.1    Uniprot ID   -
Organism   Helicobacter pylori strain 5-A-EK1     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 990148..1001932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4G81_RS04750 motB 990911..991684 (+) 774 WP_139524402.1 flagellar motor protein MotB -
  D4G81_RS04755 - 991690..992127 (+) 438 WP_001875392.1 hypothetical protein -
  D4G81_RS04760 - 992196..993857 (+) 1662 WP_139524404.1 ABC transporter permease/substrate-binding protein -
  D4G81_RS04765 - 993861..994511 (+) 651 WP_139524405.1 ATP-binding cassette domain-containing protein -
  D4G81_RS04770 - 994515..994694 (-) 180 WP_000468793.1 hypothetical protein -
  D4G81_RS04775 - 994686..995147 (+) 462 WP_139524407.1 hypothetical protein -
  D4G81_RS04780 uvrC 995148..996932 (+) 1785 WP_139524409.1 excinuclease ABC subunit UvrC Machinery gene
  D4G81_RS04785 - 996943..998208 (+) 1266 WP_139524411.1 homoserine dehydrogenase -
  D4G81_RS04790 - 998208..998552 (+) 345 WP_047419110.1 YraN family protein -
  D4G81_RS04795 trxA 998641..998961 (+) 321 WP_000020199.1 thioredoxin -
  D4G81_RS04800 trxB 998966..999901 (+) 936 WP_139524413.1 thioredoxin-disulfide reductase -
  D4G81_RS04805 - 1000113..1000934 (+) 822 WP_139524414.1 glycosyltransferase family 25 protein -
  D4G81_RS04810 - 1001170..1001418 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68668.97 Da        Isoelectric Point: 9.7790

>NTDB_id=320361 D4G81_RS04780 WP_139524409.1 995148..996932(+) (uvrC) [Helicobacter pylori strain 5-A-EK1]
MADLLSSLKNLPHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNYRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKKCLEMIENKDRLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNEALKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFNLECVPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNTVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=320361 D4G81_RS04780 WP_139524409.1 995148..996932(+) (uvrC) [Helicobacter pylori strain 5-A-EK1]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATTATCGCACTAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAAAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGCGAGCAATAAGGCGGT
GTTGGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTCAACGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTGTTGAGT
GCTTGCTCTAATGAAGCACTTAAAGAATTGCAAGATTTTATCTCCCATCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAGGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTTCAAAAAAACTCTTATCGGCG
TTACCATTTAAAAGGCTCTAATGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGAGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATCAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCTAGCGTGAAAAAATTATTAGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CACCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.475

100

0.975

Multiple sequence alignment